|
rs1001179
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Furthermore, we did not find any statistically significant differences in rates between CAT rs1001179 and CTSD rs17571 genotypes and AD controlling for APOE e4 allele status.
|
18248894 |
2008 |
|
rs10046
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In addition, our results demonstrated that homozygous TT genotype in rs10046, dominant AA and AG genotypes in rs767199, homozygous TT genotype in rs727479, and dominant TT and TA genotypes in rs1143704 might be the susceptibility genotypes for AD, while no associations were observed between rs1065778, rs1062033, rs1008805, and rs700519 polymorphisms and AD susceptibility.
|
31278540 |
2019 |
|
rs10051644
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Haplotype analysis indicated that the T-A-C-A-T-C-C and T-G-C-A-T-C-C haplotypes in the southwestern cohort and the T-G-C-G-C-T-C haplotype in the eastern cohort, consisting of rs10051644, rs6869634, rs3797617, rs3756577, rs4958445, rs10515639 and rs6881743, showed a significant association with AD (<i>P</i> = 0.037, <i>P</i> = 0.026 and <i>P</i> = 0.045, respectively).
|
31031618 |
2019 |
|
rs1007837
|
|
|
0.700 |
GeneticVariation |
GWASDB |
GAB2 alleles modify Alzheimer's risk in APOE epsilon4 carriers.
|
17553421 |
2007 |
|
rs10078434
|
|
T |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide association study of Alzheimer's disease endophenotypes at prediagnosis stages.
|
29274321 |
2018 |
|
rs10085109
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Of the four SNPs, rs10085109 in the FLT4 gene was only significantly associated with the AD phenotype in both initial and replication samples.
|
23490417 |
2013 |
|
rs1008805
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Association between rs10046, rs1143704, rs767199, rs727479, rs1065778, rs1062033, rs1008805, and rs700519 polymorphisms in aromatase (CYP19A1) gene and Alzheimer's disease risk: a systematic review and meta-analysis involving 11,051 subjects.
|
31278540 |
2019 |
|
rs10097505
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Further luciferase assay, data mining, and integrative analyses revealed that the AD-risk genotype AA of rs10097505 was associated with an increased Arc mRNA expression and an elevated Aβ level.
|
28108859 |
2018 |
|
rs10098778
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide association analysis of dementia and its clinical endophenotypes reveal novel loci associated with Alzheimer's disease and three causality networks: The GR@ACE project.
|
31473137 |
2019 |
|
rs1010159
|
|
|
0.040 |
GeneticVariation |
BEFREE |
We conducted a study of 7 single nucleotide polymorphisms (SNPs), rs668387, rs689021, rs641120, rs1699102, rs3824968, rs2282649, and rs1010159, in the SORL1 gene that were associated to AD in previous studies.
|
19584446 |
2009 |
|
rs1010159
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Analysis showed, (i) Increased risk between the single nucleotidepolymorphisms (rs641120, rs1010159) and Alzheimer's disease susceptibility inAsian populations, (ii) Single nucleotide polymorphism rs689021 was associatedwith decreased risk in Caucasians, and (iii) Single nucleotide polymorphismrs641120 was detected as a decreased risk in both populations.
|
29036834 |
2018 |
|
rs1010159
|
|
|
0.040 |
GeneticVariation |
BEFREE |
In the present study we investigated the association of SORL1 gene variants (rs2070045 (SNP19), SORL1-18ex26 (SNP21), rs3824968 (SNP23), rs1010159 (SNP25)) with AD risk by using Cox proportional hazard model and Kaplan-Meier survival analysis in 349 AD patients and 483 controls, recruited from a multicenter study of the German Competence Network Dementias.
|
19368828 |
2009 |
|
rs1010159
|
|
|
0.040 |
GeneticVariation |
BEFREE |
In the MCI cohort, rs1010159 was associated with conversion to AD (HR = 1.56, p = 0.002).
|
25881907 |
2015 |
|
rs10109834
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
GWAS on family history of Alzheimer's disease.
|
29777097 |
2018 |
|
rs10119
|
|
|
0.700 |
GeneticVariation |
GWASDB |
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
|
21460841 |
2011 |
|
rs10119
|
|
|
0.700 |
GeneticVariation |
GWASDB |
Genome-wide association study of Alzheimer's disease.
|
22832961 |
2012 |
|
rs10119
|
|
|
0.700 |
GeneticVariation |
GWASDB |
Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease.
|
19734903 |
2009 |
|
rs10137185
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A separate SNP (rs10137185) was associated with decreased risk for AD in women who identified themselves as Black (OR 0.6, 95% CI = 0.4-0.9).
|
24326520 |
2014 |
|
rs10139154
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The current study provides preliminary </span>evidence of the involvement of SCFD1 rs10139154 in the risk of developing AD.
|
31267315 |
2019 |
|
rs10164112
|
|
|
0.010 |
GeneticVariation |
BEFREE |
However, in combination with the <i>APOE</i> ε4 allele, the rs10164112-T allele has been found to be a risk factor for AD in the Han Chinese population reported in this study.
|
30666118 |
2019 |
|
rs10173717
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In this cohort, we identified novel loci genome-wide significantly associated as modifiers of the age of onset of AD (CD44, rs187116, P=1.29 × 10⁻¹²; NPHP1, rs10173717, P=1.74 × 10⁻¹²; CADPS2, rs3757536, P=1.54 × 10⁻¹⁰; GREM2, rs12129547, P=1.69 × 10⁻¹³, among others) as well as other loci known to be associated with AD.
|
22710270 |
2013 |
|
rs10194375
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
GWAS on family history of Alzheimer's disease.
|
29777097 |
2018 |
|
rs10207628
|
|
|
0.800 |
GeneticVariation |
GWASDB |
Genome-wide association study of Alzheimer's disease with psychotic symptoms.
|
22005930 |
2012 |
|
rs10207628
|
|
|
0.800 |
GeneticVariation |
GWASCAT |
Genome-wide association study of Alzheimer's disease with psychotic symptoms.
|
22005930 |
2012 |
|
rs10222981
|
|
T |
0.700 |
GeneticVariation |
GWASCAT |
Genetic data and cognitively defined late-onset Alzheimer's disease subgroups.
|
30514930 |
2018 |