Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs13048019
rs13048019
TIAM1
0.810 GeneticVariation BEFREE Recently, four single nucleotide polymorphisms (SNPs), including rs2814707 in the 9p21, rs12608932 in the UNC13A gene, rs13048019 in the TIMA1 gene, and rs2228576 in the SCNN1A gene have been reported to be associated with the risk for developing amyotrophic lateral sclerosis (ALS) in Caucasian population. 24493373

2014
dbSNP: rs13048019
rs13048019
TIAM1
T 0.810 GeneticVariation GWASDB Chromosome 9p21 in amyotrophic lateral sclerosis in Finland: a genome-wide association study. 20801718

2010
dbSNP: rs3113494
rs3113494 		0.810 GeneticVariation BEFREE Although no SNPs reached genome-wide significance in the discovery phase for either phenotype, three SNPs were statistically significant in the replication analysis of ALS outcome: rs6080539 (177 kb from PCSK2), rs7000234 (4 kb from ZNF704), and rs3113494 (13 kb from LOC100506746). 22470424

2012
dbSNP: rs3113494
rs3113494 		0.810 GeneticVariation GWASCAT Although no SNPs reached genome-wide significance in the discovery phase for either phenotype, three SNPs were statistically significant in the replication analysis of ALS outcome: rs6080539 (177 kb from PCSK2), rs7000234 (4 kb from ZNF704), and rs3113494 (13 kb from LOC100506746). 22470424

2012
dbSNP: rs3113494
rs3113494 		0.810 GeneticVariation GWASDB Although no SNPs reached genome-wide significance in the discovery phase for either phenotype, three SNPs were statistically significant in the replication analysis of ALS outcome: rs6080539 (177 kb from PCSK2), rs7000234 (4 kb from ZNF704), and rs3113494 (13 kb from LOC100506746). 22470424

2012
dbSNP: rs4363506
rs4363506 		0.810 GeneticVariation BEFREE Our two-locus analysis showed that two two-locus combinations--rs4363506 (SNP1) and rs3733242 (SNP2), and rs4363506 and rs16984239 (SNP3) -- were significantly associated with sporadic ALS. 19740415

2009
dbSNP: rs4363506
rs4363506 		0.810 GeneticVariation GWASDB Genome-wide genotyping in amyotrophic lateral sclerosis and neurologically normal controls: first stage analysis and public release of data. 17362836

2007
dbSNP: rs4363506
rs4363506 		0.810 GeneticVariation GWASCAT Genome-wide genotyping in amyotrophic lateral sclerosis and neurologically normal controls: first stage analysis and public release of data. 17362836

2007
dbSNP: rs6703183
rs6703183
LOC105372898
A 0.810 GeneticVariation GWASCAT We discovered two new susceptibility loci for ALS at 1q32 (CAMK1G, rs6703183, Pcombined = 2.92 × 10(-8), odds ratio (OR) = 1.31) and 22p11 (CABIN1 and SUSD2, rs8141797, Pcombined = 2.35 × 10(-9), OR = 1.52). 23624525

2013
dbSNP: rs6703183
rs6703183
LOC105372898
A 0.810 GeneticVariation GWASDB We discovered two new susceptibility loci for ALS at 1q32 (CAMK1G, rs6703183, Pcombined = 2.92 × 10(-8), odds ratio (OR) = 1.31) and 22p11 (CABIN1 and SUSD2, rs8141797, Pcombined = 2.35 × 10(-9), OR = 1.52). 23624525

2013
dbSNP: rs6703183
rs6703183
LOC105372898
0.810 GeneticVariation BEFREE We discovered two new susceptibility loci for ALS at 1q32 (CAMK1G, rs6703183, Pcombined = 2.92 × 10(-8), odds ratio (OR) = 1.31) and 22p11 (CABIN1 and SUSD2, rs8141797, Pcombined = 2.35 × 10(-9), OR = 1.52). 23624525

2013
dbSNP: rs7477
rs7477
PIGL ; CENPV
T 0.810 GeneticVariation GWASCAT Eight genomic regions provided evidence of association with ALS, including 9p21.2 (rs3849942, odds ratio [OR] = 1.21; p = 4.41 × 10(-7)), 17p11.2 (rs7477, OR = 1.30; p = 2.89 × 10(-7)), and 19p13 (rs12608932, OR = 1.37, p = 1.29 × 10(-7)). 22959728

2013
dbSNP: rs7477
rs7477
PIGL ; CENPV
T 0.810 GeneticVariation GWASDB Eight genomic regions provided evidence of association with ALS, including 9p21.2 (rs3849942, odds ratio [OR] = 1.21; p = 4.41 × 10(-7)), 17p11.2 (rs7477, OR = 1.30; p = 2.89 × 10(-7)), and 19p13 (rs12608932, OR = 1.37, p = 1.29 × 10(-7)). 22959728

2013
dbSNP: rs7477
rs7477
PIGL ; CENPV
0.810 GeneticVariation BEFREE Eight genomic regions provided evidence of association with ALS, including 9p21.2 (rs3849942, odds ratio [OR] = 1.21; p = 4.41 × 10(-7)), 17p11.2 (rs7477, OR = 1.30; p = 2.89 × 10(-7)), and 19p13 (rs12608932, OR = 1.37, p = 1.29 × 10(-7)). 22959728

2013
dbSNP: rs7477
rs7477
PIGL ; CENPV
A 0.810 GeneticVariation GWASCAT C9orf72 and UNC13A are shared risk loci for amyotrophic lateral sclerosis and frontotemporal dementia: a genome-wide meta-analysis. 24931836

2014
dbSNP: rs8141797
rs8141797
SUSD2
G 0.810 GeneticVariation GWASCAT We discovered two new susceptibility loci for ALS at 1q32 (CAMK1G, rs6703183, Pcombined = 2.92 × 10(-8), odds ratio (OR) = 1.31) and 22p11 (CABIN1 and SUSD2, rs8141797, Pcombined = 2.35 × 10(-9), OR = 1.52). 23624525

2013
dbSNP: rs8141797
rs8141797
SUSD2
0.810 GeneticVariation BEFREE We discovered two new susceptibility loci for ALS at 1q32 (CAMK1G, rs6703183, Pcombined = 2.92 × 10(-8), odds ratio (OR) = 1.31) and 22p11 (CABIN1 and SUSD2, rs8141797, Pcombined = 2.35 × 10(-9), OR = 1.52). 23624525

2013
dbSNP: rs8141797
rs8141797
SUSD2
G 0.810 GeneticVariation GWASDB We discovered two new susceptibility loci for ALS at 1q32 (CAMK1G, rs6703183, Pcombined = 2.92 × 10(-8), odds ratio (OR) = 1.31) and 22p11 (CABIN1 and SUSD2, rs8141797, Pcombined = 2.35 × 10(-9), OR = 1.52). 23624525

2013
dbSNP: rs10122902
rs10122902
C9orf72
G 0.800 GeneticVariation GWASCAT Chromosome 9p21 in sporadic amyotrophic lateral sclerosis in the UK and seven other countries: a genome-wide association study. 20801717

2010
dbSNP: rs10122902
rs10122902
C9orf72
0.800 GeneticVariation GWASDB Chromosome 9p21 in sporadic amyotrophic lateral sclerosis in the UK and seven other countries: a genome-wide association study. 20801717

2010
dbSNP: rs10438933
rs10438933
B4GALT6
G 0.800 GeneticVariation GWASCAT Reduced expression of the Kinesin-Associated Protein 3 (KIFAP3) gene increases survival in sporadic amyotrophic lateral sclerosis. 19451621

2009
dbSNP: rs10438933
rs10438933
B4GALT6
G 0.800 GeneticVariation GWASDB Reduced expression of the Kinesin-Associated Protein 3 (KIFAP3) gene increases survival in sporadic amyotrophic lateral sclerosis. 19451621

2009
dbSNP: rs11082762
rs11082762
LAMA3
A 0.800 GeneticVariation GWASCAT Age of onset of amyotrophic lateral sclerosis is modulated by a locus on 1p34.1. 22959728

2013
dbSNP: rs11082762
rs11082762
LAMA3
A 0.800 GeneticVariation GWASDB Age of onset of amyotrophic lateral sclerosis is modulated by a locus on 1p34.1. 22959728

2013
dbSNP: rs1971791
rs1971791 		G 0.800 GeneticVariation GWASCAT Age of onset of amyotrophic lateral sclerosis is modulated by a locus on 1p34.1. 22959728

2013