Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1008438
rs1008438
0.010 GeneticVariation BEFREE An analysis was made of the association of two single nucleotide polymorphisms (db rs1008438 -110A/C and db rs1043618 +190 G/C) with circulating and intragranulocytic HSPA1A and the risk of atherosclerosis. 22328194

2012

dbSNP: rs1010
rs1010
0.010 GeneticVariation BEFREE We considered five variants that were associated with coronary heart disease in two studies and confirmed in the Atherosclerosis Risk in Communities study: rs20455 (KIF6), rs3900940 (MYH15), rs7439293 (PALLD), rs2298566 (SNX19), and rs1010 (VAMP8). 18073581

2007

dbSNP: rs1020608562
rs1020608562
0.010 GeneticVariation BEFREE We aimed to investigate the associations of fractalkine receptor (CX3CR1) V249I, T280M and CCR5-59029 A/G gene polymorphisms in chronic renal failure (CRF) subjects undergoing hemodialysis and to evaluate possible associations of these polymorphisms with hypertension (HT), diabetes mellitus (DM) and atherosclerosis (AS). 27118566

2016

dbSNP: rs1022113606
rs1022113606
0.010 GeneticVariation BEFREE In our study, the Thr40Ala and Arg213Gly polymorphic variants of the EC-SOD gene (SOD ( 3 )) were investigated for associations with atherosclerosis and other related factors in 144 subjects with significant atheroma (having one, two, or three major coronary arteries with >50% obstruction, and/or peripheral artery lesions, and/or carotid artery stenosis demonstrated by angiography and echography) and in 150 subjects with no significant atheroma. 18726685

2008

dbSNP: rs1042713
rs1042713
0.010 GeneticVariation BEFREE ADRB2 Arg16Gly polymorphism, lung function, and mortality: results from the Atherosclerosis Risk in Communities study. 17356698

2007

dbSNP: rs1043618
rs1043618
0.010 GeneticVariation BEFREE An analysis was made of the association of two single nucleotide polymorphisms (db rs1008438 -110A/C and db rs1043618 +190 G/C) with circulating and intragranulocytic HSPA1A and the risk of atherosclerosis. 22328194

2012

dbSNP: rs10455872
rs10455872
LPA
0.010 GeneticVariation BEFREE It is unclear whether the LPA variants rs10455872 and rs3798220, which correlate with lipoprotein(a) levels and coronary artery disease (CAD), confer susceptibility predominantly via atherosclerosis or thrombosis. 22898070

2012

dbSNP: rs1051931
rs1051931
0.010 GeneticVariation BEFREE We investigated whether Lp-PLA2 activity and PLA2G7 A379V genotype were related to mediators of atherosclerosis in a diabetic study. 16438975

2006

dbSNP: rs1056515
rs1056515
0.010 GeneticVariation BEFREE Our study identifies a common variant rs1056515 as a genetic marker for CAD and rare variants in LD with rs1056515 leading to decreased expression of RGS5, which contributes to atherosclerosis by impairing endothelial cell function. 31605122

2019

dbSNP: rs1061170
rs1061170
CFH
0.030 GeneticVariation BEFREE In this study, we examined whether the gene-gene interactions between CRP haplotypes and CFH Tyr402His functional polymorphism exerted an effect on early atherosclerosis. 19076828

2009

dbSNP: rs1061170
rs1061170
CFH
0.030 GeneticVariation BEFREE In addition, a specific Y402H polymorphism of the complement inhibitor factor H has been found to be associated with the incidence of both AMD and AS. 22067048

2012

dbSNP: rs1061170
rs1061170
CFH
0.030 GeneticVariation BEFREE We evaluated the association of the Y402H polymorphism with incident coronary heart disease (CHD), incident ischemic stroke, and carotid artery wall thickness (intima-media thickness (IMT)) in the Atherosclerosis Risk in Communities (ARIC) cohort. 18292760

2008

dbSNP: rs10757274
rs10757274
0.010 GeneticVariation BEFREE The 9p21 SNP (rs10757274) and multiple risk markers were measured in the Atherosclerosis Risk in Communities Study, and incident coronary disease events were ascertained. 22935634

2012

dbSNP: rs10757278
rs10757278
0.010 GeneticVariation BEFREE we tested the hypothesis that the 9p21 risk locus promotes atherosclerosis by examining the association between rs10757278 and coronary artery disease (CAD) severity and progression determined by semi-quantitative angiographic scores. 20729229

2010

dbSNP: rs10846744
rs10846744
0.040 GeneticVariation BEFREE Variation in SCARB1 at rs10846744 was significantly associated with CCIMT across racial/ethnic groups in Multi-Ethnic Study of Atherosclerosis. 20160195

2010

dbSNP: rs10846744
rs10846744
0.040 GeneticVariation BEFREE The SCARB1 SNP, rs10846744, exerts a major effect on subclinical atherosclerosis and incident cardiovascular disease in humans. 22628436

2012

dbSNP: rs10846744
rs10846744
0.040 GeneticVariation BEFREE We identified a potentially novel connection between rs10846744, the immune checkpoint inhibitor lymphocyte activation gene 3 (<i>LAG3</i>), and atherosclerosis. 27777974

2016

dbSNP: rs10846744
rs10846744
0.040 GeneticVariation BEFREE SCARB1 rs10846744 is significantly associated with Lp-PLA2 activity, atherosclerosis, and CVD events, but Lp-PLA2 activity is not a mediator in the association of rs10846744 with cIMT in MESA. 30289950

2018

dbSNP: rs11209026
rs11209026
0.010 GeneticVariation BEFREE Analysis of the association between IL-23R rs11209026 polymorphism and incidence of atherosclerosis. 26261042

2015

dbSNP: rs1122608
rs1122608
0.010 GeneticVariation BEFREE Further studies were used to identify the most likely mechanism by which rs1122608 regulates atherosclerosis. 24190014

2014

dbSNP: rs1126478
rs1126478
LTF
0.010 GeneticVariation BEFREE The relationships among lactoferrin genotypes, lactoferrin concentrations, and clinical factors on the risk for atherosclerosis are not fully understood, but the G allele of rs1126478 seems to have a detrimental effect in a European population. 22406253

2012

dbSNP: rs112735431
rs112735431
0.010 GeneticVariation BEFREE The p.R4810K heterozygous variant was identified in 5 patients, including 3 patients with atherosclerosis, 1 patient with Graves disease, and 1 patient with rheumatoid arthritis; it was also observed in one control. 28063898

2017

dbSNP: rs1130864
rs1130864
CRP
0.020 GeneticVariation BEFREE We genotyped 3 tag single nucleotide polymorphisms (SNPs) [+1444T>C (rs1130864); +2303G>A (rs1205) and +4899T>G (rs 3093077)] in the CRP gene and assessed CRP and carotid intima-media thickness (CIMT), a structural marker of atherosclerosis, in 4941 men and women aged 50-74 (mean 61) years (the Whitehall II Study). 18714381

2008

dbSNP: rs1130864
rs1130864
CRP
0.020 GeneticVariation BEFREE We concluded that rs3091244, rs1130864 and the T-T-G haplotype are genetic markers for elevated basal CRP levels. rs1800947 and the C-C-C haplotype appear to be susceptibility markers for atherosclerosis, but this requires confirmation. 16832152

2006

dbSNP: rs1137100
rs1137100
0.020 GeneticVariation BEFREE To evaluate the potential contribution of LEPrs2167270(19 G/A), LEPRrs1137100(326 A/G) and ADIPOQrs1501299(276 G/T) gene polymorphisms in psoriasis susceptibility and their influence in epicardial adipose tissue and abdominal visceral fat volume and subclinical atherosclerosis in severe psoriasis patients. 26123401

2015