rs121434500
|
|
A |
0.700 |
GeneticVariation |
CLINVAR |
|
|
|
rs199473260
|
|
C |
0.700 |
GeneticVariation |
CLINVAR |
|
|
|
rs7164883
|
|
|
0.820 |
GeneticVariation |
BEFREE |
<b>Conclusion:</b><i>HCN4</i> rs498005 and rs7164883 polymorphisms are significantly associated with AF risk.
|
31315459 |
2019 |
rs498005
|
|
|
0.010 |
GeneticVariation |
BEFREE |
<b>Conclusion:</b><i>HCN4</i> rs4980</span>05 and rs7164883 polymorphisms are significantly associated with AF risk.
|
31315459 |
2019 |
rs147750704
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The aim of this simulation study was to identify at cell and tissue levels' mechanisms by which increased I(K1) facilitates and perpetuates AF.The Courtemanche et al. human atrial cell action potential (AP) model was modified to incorporate reported changes in I(K1) induced by the Kir2.1 V93I mutation in both heterozygous (Het) and homozygous (Hom) mutant forms.
|
19041665 |
2009 |
rs5443
|
|
|
0.010 |
GeneticVariation |
BEFREE |
C825T polymorphism of the G-protein beta3 subunit gene and atrial fibrillation: association of the TT genotype with a reduced risk for atrial fibrillation.
|
15389246 |
2004 |
rs1805127
|
|
|
0.100 |
GeneticVariation |
BEFREE |
G38S polymorphism in the MinK gene could be used as a genetic marker of risk of lone AF.
|
17165161 |
2006 |
rs199473457
|
|
|
0.010 |
GeneticVariation |
BEFREE |
R231C mutation in KCNQ1 causes long QT syndrome type 1 and familial atrial fibrillation.
|
20850564 |
2011 |
rs956828658
|
|
|
0.010 |
GeneticVariation |
BEFREE |
R231C mutation in KCNQ1 causes long QT syndrome type 1 and familial atrial fibrillation.
|
20850564 |
2011 |
rs58238559
|
|
|
0.010 |
GeneticVariation |
BEFREE |
rs58238559 in ABCB4 is a rare missense variant with a significant effect on the development of AFL/AF.
|
25888430 |
2015 |
rs2890565
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Ser89Asn polymorphisms of the UTS2 gene are significantly associated with atrial fibrillation in the Chinese population.
|
26811505 |
2016 |
rs2200733
|
|
|
0.900 |
GeneticVariation |
BEFREE |
rs2200733 risk allele at the 4q25 predicted impaired clinical response to catheter ablation for AF in Chinese Han population.
|
27843048 |
2017 |
rs768138092
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A heterozygous missense mutation (p.P33R) was identified in the SND cohort and four heterozygous variants (p.G77D, p.L129=, p.L130F, p.A293=) in the AF cohort.
|
31354791 |
2019 |
rs1291725984
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A heterozygous missense mutation (p.P33R) was identified in the SND cohort and four heterozygous variants (p.G77D, p.L129=, p.L130F, p.A293=) in the AF cohort.
|
31354791 |
2019 |
rs1799983
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A multiple logistic regression analysis showed that presence of the rs1799983 variant (OR 1.75, 95% CI 1.07-2.86, p=0.026) and persistent AF were independent predictors for ERAF after AF ablation.
|
26256966 |
2015 |
rs28933093
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A new missense (E161K) mutation was identified in a family with early atrial fibrillation and a previously described (R377H) mutation in another family with a quadriceps myopathy associated with DCM.
|
12920062 |
2003 |
rs61672878
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A new missense (E161K) mutation was identified in a family with early atrial fibrillation and a previously described (R377H) mutation in another family with a quadriceps myopathy associated with DCM.
|
12920062 |
2003 |
rs587777556
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A novel A130V mutation was identified in a 46-year-old patient with lone AF, and the mutation was absent in 500 controls.
|
20558140 |
2010 |
rs199472708
|
|
|
0.030 |
GeneticVariation |
BEFREE |
A novel KCNQ1-G229D mutation identified in a juvenile-onset AF patient altered the IKs activity and kinetics, thereby increasing the arrhythmogenicity to AF.
|
24096004 |
2014 |
rs199472952
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A novel KCNQ1-G229D mutation identified in a juvenile-onset AF patient altered the IKs activity and kinetics, thereby increasing the arrhythmogenicity to AF.
|
24096004 |
2014 |
rs781255319
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A novel KCNQ1-G229D mutation identified in a juvenile-onset AF patient altered the IKs activity and kinetics, thereby increasing the arrhythmogenicity to AF.
|
24096004 |
2014 |
rs199473324
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A novel SCN5A gain-of-function mutation M1875T associated with familial atrial fibrillation.
|
18929244 |
2008 |
rs2200733
|
|
|
0.900 |
GeneticVariation |
GWASCAT |
A sequence variant in ZFHX3 on 16q22 associates with atrial fibrillation and ischemic stroke.
|
19597491 |
2009 |
rs2200733
|
|
|
0.900 |
GeneticVariation |
GWASDB |
A sequence variant in ZFHX3 on 16q22 associates with atrial fibrillation and ischemic stroke.
|
19597491 |
2009 |
rs2220427
|
|
|
0.800 |
GeneticVariation |
GWASDB |
A sequence variant in ZFHX3 on 16q22 associates with atrial fibrillation and ischemic stroke.
|
19597491 |
2009 |