|
rs1057519904
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Diffuse intrinsic pontine gliomas (DIPGs) are highly aggressive pediatric brain tumors that are characterized by a recurrent mutation (K27M) within the histone H3 encoding genes H3F3A or HIST1H3A/B/C.
|
30943283 |
2019 |
|
rs3761549
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The allele C of rs3761549 is lower in the brain tumour cases when compared with the controls (364 vs 392, P = 0.005).
|
30802341 |
2019 |
|
rs603965
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our findings suggested that CCND1 rs603965 polymorphism may serve as a potential genetic biomarker of brain tumor, especially for glioma.
|
30972946 |
2019 |
|
rs777169839
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Expression of PGC-1α K224R mutant significantly increases mitochondrial biogenesis, reactive oxygen species (ROS) production, and tumor cell apoptosis under hypoxia and inhibits brain tumor growth in mice.
|
31629659 |
2019 |
|
rs779707422
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Therefore, we confirm that FGFR1 N546K is a plausible causative mutation of ECCL patients and could be associated with a risk of brain tumor development.
|
31173478 |
2019 |
|
rs78378222
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A noncoding polymorphism (rs78378222) in TP53, carried by scores of millions of people, was previously associated with moderate risk of brain tumors and other neoplasms.
|
31699989 |
2019 |
|
rs11554137
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Prevalence of the single-nucleotide polymorphism rs11554137 (IDH1<sup>105GGT</sup>) in brain tumors of a cohort of Italian patients.
|
29535392 |
2018 |
|
rs374052197
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Patients/Methods In a prospective cohort study, intratumoral IDH1 R132H mutation and podoplanin were determined in brain tumor specimens (mainly glioma) by immunohistochemistry.
|
29676036 |
2018 |
|
rs397516813
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The novel RAF1 mutation p.(Gly361Ala) located outside the kinase domain of the CR3 region in two patients with Noonan syndrome, including one with a rare brain tumor.
|
29271604 |
2018 |
|
rs745934102
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Patients/Methods In a prospective cohort study, intratumoral IDH1 R132H mutation and podoplanin were determined in brain tumor specimens (mainly glioma) by immunohistochemistry.
|
29676036 |
2018 |
|
rs104894229
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Further, one of the patients (c.35G>A; p.(Gly12Asp)) had a myeloproliferative disorder, and one subject (c.34G>C; p.(Gly12Arg)) exhibited an uncharacterized brain tumour.
|
28594414 |
2017 |
|
rs1052576
|
|
|
0.010 |
GeneticVariation |
BEFREE |
CASP-9 (rs1052576) mutant A allele seems to be a protective factor for glioma brain tumor.
|
28870924 |
2017 |
|
rs11568821
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The aims of this study were to assess the association of two single nucleotide polymorphisms in the PD-1 gene, PD-1.5 (+7785 C/T-rs2227981) and PD-1.3 (+7146 G/A- rs11568821), with benign and malignant brain tumors.
|
28535114 |
2017 |
|
rs121913237
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Further, one of the patients (c.35G>A; p.(Gly12Asp)) had a myeloproliferative disorder, and one subject (c.34G>C; p.(Gly12Arg)) exhibited an uncharacterized brain tumour.
|
28594414 |
2017 |
|
rs121913250
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Further, one of the patients (c.35G>A; p.(Gly12Asp)) had a myeloproliferative disorder, and one subject (c.34G>C; p.(Gly12Arg)) exhibited an uncharacterized brain tumour.
|
28594414 |
2017 |
|
rs121913530
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Further, one of the patients (c.35G>A; p.(Gly12Asp)) had a myeloproliferative disorder, and one subject (c.34G>C; p.(Gly12Arg)) exhibited an uncharacterized brain tumour.
|
28594414 |
2017 |
|
rs1333049
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The goal of this study was to evaluate the contribution of <i>CDKN2B-AS1</i> rs1333049 to the risk of hemorrhagic stroke (HS) and brain tumor (BT) in Han Chinese.
|
28138111 |
2017 |
|
rs2227981
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The aims of this study were to assess the association of two single nucleotide polymorphisms in the PD-1 gene, PD-1.5 (+7785 C/T-rs2227981) and PD-1.3 (+7146 G/A- rs11568821), with benign and malignant brain tumors.
|
28535114 |
2017 |
|
rs754820004
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Replacement of wild-type Bcl2 with phosphorylation-deficient Bcl2 T69A mutant sensitizes glioma cells to oxidative stress-induced apoptosis and impairs brain tumor formation in an orthotopic xenograft model.
|
28035139 |
2017 |
|
rs771563543
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Mean CBF1 expression is significantly increased in isocitrate dehydrogenase 1 (IDH1) R132H mutant glioblastoma and serves as prognostic marker for prolonged overall survival in brain tumours, particularly after therapy with temozolomide.
|
28571041 |
2017 |
|
rs774265827
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This study evaluates the presence of R132H mutation in isocitrate dehydrogenase (<i>IDH1</i>) gene and the vascular endothelial growth factor (<i>VEGF</i>) +936 C/T polymorphism in brain tumors.
|
28948065 |
2017 |
|
rs11615
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In the present work, we carried out a comprehensive meta-analysis of results from all published data (5 data sets for rs116</span>15, 7 for rs3212986, 11 for rs13181, 5 for rs1799793, 3 for rs238406, and 4 for rs17655) to evaluate risk of brain tumors contributed by the polymorphisms being investigated.
|
26264164 |
2016 |
|
rs13181
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In the present work, we carried out a comprehensive meta-analysis of results from all published data (5 data sets for rs11615, 7 for rs3212986, 11 for rs13181, 5 for rs1799793, 3 for rs238406, and 4 for rs17655) to evaluate risk of brain tumors contributed by the polymorphisms being investigated.
|
26264164 |
2016 |
|
rs17655
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In the present work, we carried out a comprehensive meta-analysis of results from all published data (5 data sets for rs11615, 7 for rs3212986, 11 for rs13181, 5 for rs1799793, 3 for rs238406, and 4 for rs17655) to evaluate risk of brain tumors contributed by the polymorphisms being investigated.
|
26264164 |
2016 |
|
rs1799793
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In the present work, we carried out a comprehensive meta-analysis of results from all published data (5 data sets for rs11615, 7 for rs3212986, 11 for rs13181, 5 for rs1799793, 3 for rs238406, and 4 for rs17655) to evaluate risk of brain tumors contributed by the polymorphisms being investigated.
|
26264164 |
2016 |