rs1052133
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Subgroup analyses revealed significant association of OGG1 rs1052133 with rectal cancer risk.
|
28749454 |
2017 |
rs1800471
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Single Nucleotide Polymorphism TGFβ1 R25P Correlates with Acute Toxicity during Neoadjuvant Chemoradiotherapy in Rectal Cancer Patients.
|
28333014 |
2017 |
rs770507184
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Single Nucleotide Polymorphism TGFβ1 R25P Correlates with Acute Toxicity during Neoadjuvant Chemoradiotherapy in Rectal Cancer Patients.
|
28333014 |
2017 |
rs4646903
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Carriers of the CYP1A1 rs4646903 CC homozygous variant showed a reduced risk of rectal cancer compared with that in TT carriers.
|
28273931 |
2017 |
rs397507444
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Although the MTHFR A1298C polymorphism was not associated with OS in CRC, this polymorphism was associated with significantly shorter OS in rectal cancer.
|
28044213 |
2017 |
rs17268122
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The screening of ABCC4 rs17268122 tagSNP and the Mandard tumor response in clinical practice may help to identify patients with different rectal cancer prognosis and contribute to an individualized therapeutic decision tree.
|
28011504 |
2017 |
rs1042522
|
|
|
0.030 |
GeneticVariation |
BEFREE |
These results suggest that the TP53 Arg72Pro polymorphism CC genotype may contribute to an increased risk of CRC, especially for rectal cancer and among Asians.
|
27901479 |
2017 |
rs1131691014
|
|
|
0.020 |
GeneticVariation |
BEFREE |
These results suggest that the TP53 Arg72Pro polymorphism CC genotype may contribute to an increased risk of CRC, especially for rectal cancer and among Asians.
|
27901479 |
2017 |
rs878854066
|
|
|
0.020 |
GeneticVariation |
BEFREE |
These results suggest that the TP53 Arg72Pro polymorphism CC genotype may contribute to an increased risk of CRC, especially for rectal cancer and among Asians.
|
27901479 |
2017 |
rs1799929
|
|
|
0.010 |
GeneticVariation |
BEFREE |
High fried red meat intake associated with NAT2-T341C, G590A, G857A, A845C, and C48</span>1T rapid acetylator allele determines a risk of 2.39 (P=.002), 2.39 (P=.002), 2.37 (P=.002), 2.28 (P=.004), and 2.51 (P=.001), respectively, for colon cancer, whereas in the case of rectal cancer, the risk increased to 7.55 (P<.001), 7.7 (P<.001), 7.83 (P<.001), 7.51 (P<.001), and 8.62 (P<.001), respectively.
|
27883249 |
2017 |
rs1800449
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The relationship among the lysyl oxidase (LOX) G473A single nucleotide polymorphism (SNP), cigarette smoking and lung, colorectal, colon and rectum cancer susceptibility was studied in 200 cases of lung cancer, 335 cases of colorectal cancer including 130 cases of colon cancer and 205 cases of rectum cancer, and 335 healthy people in Tangshan, China.
|
27367711 |
2016 |
rs1800925
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Can an IL13 -1112 C/T (rs1800925) polymorphism predict responsiveness to neoadjuvant chemoradiotherapy and survival of Chinese Han patients with locally advanced rectal cancer?
|
27167201 |
2016 |
rs4939827
|
|
|
0.020 |
GeneticVariation |
BEFREE |
A significant association of SNP in SMAD7 rs4939827 and CHI3L1 rs4950928 was revealed between the rectal cancer and colon cancer patients.
|
26779637 |
2016 |
rs4950928
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A significant association of SNP in SMAD7 rs4939827 and CHI3L1 rs4950928 was revealed between the rectal cancer and colon cancer patients.
|
26779637 |
2016 |
rs9365723
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Furthermore, we found that rs9365723 was associated with an increased risk only for colon cancer but not rectal cancer (p = 0.009 and p = 0.414, respectively).
|
26616230 |
2016 |
rs397507444
|
|
|
0.060 |
GeneticVariation |
BEFREE |
The pooled analysis results indicated that MTHFR C677T might be correlated with the tumor response to pRCT under the recessive model (CC vs. CTTT) in overall analysis (OR=1.426(1.074-1.894), P=0.014), rectal cancer (OR=1.483(1.102-1.996), P=0.009), and TRG 1-2 vs. 3-5 group (OR=1.423(1.046-1.936), P=0.025), while other polymorphism including MTHFR A1298C, EGFR G497A, and EGFR CA repeat polymorphisms exerted significant association under all genetic models in overall analysis or subgroup analysis.
|
26456456 |
2015 |
rs1217691063
|
|
|
0.050 |
GeneticVariation |
BEFREE |
The pooled analysis results indicated that MTHFR C677T might be correlated with the tumor response to pRCT under the recessive model (CC vs. CTTT) in overall analysis (OR=1.426(1.074-1.894), P=0.014), rectal cancer (OR=1.483(1.102-1.996), P=0.009), and TRG 1-2 vs. 3-5 group (OR=1.423(1.046-1.936), P=0.025), while other polymorphism including MTHFR A1298C, EGFR G497A, and EGFR CA repeat polymorphisms exerted significant association under all genetic models in overall analysis or subgroup analysis.
|
26456456 |
2015 |
rs750713244
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The pooled analysis results indicated that MTHFR C677T might be correlated with the tumor response to pRCT under the recessive model (CC vs. CTTT) in overall analysis (OR=1.426(1.074-1.894), P=0.014), rectal cancer (OR=1.483(1.102-1.996), P=0.009), and TRG 1-2 vs. 3-5 group (OR=1.423(1.046-1.936), P=0.025), while other polymorphism including MTHFR A1298C, EGFR G497A, and EGFR CA repeat polymorphisms exerted significant association under all genetic models in overall analysis or subgroup analysis.
|
26456456 |
2015 |
rs14035
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Stratified analysis revealed the RAN rs14035 combined CT+TT genotype was associated with decreased CRC risk in male patients without diabetes mellitus (DM) and in patients with rectal cancer.
|
26147304 |
2015 |
rs113488022
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Compared with BRAF wild type, BRAF(V600E) was a risk for poor survival (overall survival; 5 years: 62.3% vs 51.6%, P=0.014; HR 1.43, CI 1.07-1.90, P=0.009), especially in rectal cancer (for DSS, HR: 10.60, CI: 3.04-36.92, P<0.001).
|
25973534 |
2015 |
rs121913377
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Compared with BRAF wild type, BRAF(V600E) was a risk for poor survival (overall survival; 5 years: 62.3% vs 51.6%, P=0.014; HR 1.43, CI 1.07-1.90, P=0.009), especially in rectal cancer (for DSS, HR: 10.60, CI: 3.04-36.92, P<0.001).
|
25973534 |
2015 |
rs17026425
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
A genome wide association study on Newfoundland colorectal cancer patients' survival outcomes.
|
25866641 |
2015 |
rs6854845
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
A genome wide association study on Newfoundland colorectal cancer patients' survival outcomes.
|
25866641 |
2015 |
rs113488022
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Here we report a patient with rectal cancer who carried the novel BRAF mutation VK600-601E, which has analogous molecular functions to those of the conventional BRAF mutation V600E, and may have potential as a prognostic marker for colorectal cancer (CRC).
|
25636897 |
2015 |
rs121913377
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Here we report a patient with rectal cancer who carried the novel BRAF mutation VK600-601E, which has analogous molecular functions to those of the conventional BRAF mutation V600E, and may have potential as a prognostic marker for colorectal cancer (CRC).
|
25636897 |
2015 |