|
rs1805007
|
|
|
0.020 |
GeneticVariation |
BEFREE |
These studies have shown that three RHC alleles - Arg151Cys, Arg160Trp and Asp294His - were associated with increased risk in all forms of skin cancer and with penetrance and age of onset in familial melanoma in mutation carriers.
|
12394181 |
2002 |
|
rs1805009
|
|
|
0.020 |
GeneticVariation |
BEFREE |
These studies have shown that three RHC alleles - Arg151Cys, Arg160Trp and Asp294His - were associated with increased risk in all forms of skin cancer and with penetrance and age of onset in familial melanoma in mutation carriers.
|
12394181 |
2002 |
|
rs1232547491
|
|
|
0.010 |
GeneticVariation |
BEFREE |
These studies have shown that three RHC alleles - Arg151Cys, Arg160Trp and Asp294His - were associated with increased risk in all forms of skin cancer and with penetrance and age of onset in familial melanoma in mutation carriers.
|
12394181 |
2002 |
|
rs1805008
|
|
|
0.010 |
GeneticVariation |
BEFREE |
These studies have shown that three RHC alleles - Arg151Cys, Arg160Trp and Asp294His - were associated with increased risk in all forms of skin cancer and with penetrance and age of onset in familial melanoma in mutation carriers.
|
12394181 |
2002 |
|
rs1799782
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Our data suggest that the Arg194Trp and Arg399Gln polymorphisms may be differently associated with skin cancer risk according to exposure dose and skin cancer type.
|
15381933 |
2004 |
|
rs25487
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Our data suggest that the Arg194Trp and Arg399Gln polymorphisms may be differently associated with skin cancer risk according to exposure dose and skin cancer type.
|
15381933 |
2004 |
|
rs1799793
|
|
|
0.030 |
GeneticVariation |
BEFREE |
We assessed the associations between two common nonsynonymous polymorphisms (Asp312Asn and Lys751Gln) with skin cancer risk in a nested case-control study within the Nurses' Health Study (219 melanoma, 286 squamous cell carcinoma, 300 basal cell carcinoma, and 874 controls) along with exploratory analysis on the haplotype structure of the XPD gene.
|
15941969 |
2005 |
|
rs13181
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We assessed the associations between two common nonsynonymous polymorphisms (Asp312Asn and Lys751Gln) with skin cancer risk in a nested case-control study within the Nurses' Health Study (219 melanoma, 286 squamous cell carcinoma, 300 basal cell carcinoma, and 874 controls) along with exploratory analysis on the haplotype structure of the XPD gene.
|
15941969 |
2005 |
|
rs1042522
|
|
|
0.040 |
GeneticVariation |
BEFREE |
We evaluated the association of the Arg72Pro polymorphism with skin cancer risk among Caucasians in a nested case-control study within the Nurses' Health Study (NHS) (219 melanoma, 286 squamous cell carcinoma (SCC), and 300 basal cell carcinoma (BCC) and 874 controls).
|
16739124 |
2006 |
|
rs1131691014
|
|
|
0.040 |
GeneticVariation |
BEFREE |
We evaluated the association of the Arg72Pro polymorphism with skin cancer risk among Caucasians in a nested case-control study within the Nurses' Health Study (NHS) (219 melanoma, 286 squamous cell carcinoma (SCC), and 300 basal cell carcinoma (BCC) and 874 controls).
|
16739124 |
2006 |
|
rs878854066
|
|
|
0.040 |
GeneticVariation |
BEFREE |
We evaluated the association of the Arg72Pro polymorphism with skin cancer risk among Caucasians in a nested case-control study within the Nurses' Health Study (NHS) (219 melanoma, 286 squamous cell carcinoma (SCC), and 300 basal cell carcinoma (BCC) and 874 controls).
|
16739124 |
2006 |
|
rs1217691063
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We evaluated genetic polymorphisms in the methylenetetrahydrofolate reductase (MTHFR) gene (C677T and A1298C) and the vitamin D receptor (VDR) gene (Fok1, Bsm1 and Cdx2) with skin cancer risk in a nested case-control study within the Nurses' Health Study [219 melanoma, 286 squamous cell carcinoma (SCC), 300 basal cell carcinoma (BCC) and 873 controls].
|
16950800 |
2007 |
|
rs397507444
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We evaluated genetic polymorphisms in the methylenetetrahydrofolate reductase (MTHFR) gene (C677T and A1298C) and the vitamin D receptor (VDR) gene (Fok1, Bsm1 and Cdx2) with skin cancer risk in a nested case-control study within the Nurses' Health Study [219 melanoma, 286 squamous cell carcinoma (SCC), 300 basal cell carcinoma (BCC) and 873 controls].
|
16950800 |
2007 |
|
rs749140677
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We evaluated genetic polymorphisms in the methylenetetrahydrofolate reductase (MTHFR) gene (C677T and A1298C) and the vitamin D receptor (VDR) gene (Fok1, Bsm1 and Cdx2) with skin cancer risk in a nested case-control study within the Nurses' Health Study [219 melanoma, 286 squamous cell carcinoma (SCC), 300 basal cell carcinoma (BCC) and 873 controls].
|
16950800 |
2007 |
|
rs1805007
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We studied the desensitization and internalization of three variant MC1R forms associated with red hair and increased skin cancer risk: R151C, R160W, and D294H.
|
17130136 |
2007 |
|
rs4880
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We assessed whether the functional V16A polymorphism in the MnSOD gene is associated with skin cancer risk.
|
17186424 |
2007 |
|
rs1799782
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Our data suggest that the Arg194Trp and Arg399Gln polymorphisms may be differentially associated with skin cancer risk.
|
17355263 |
2007 |
|
rs25487
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Our data suggest that the Arg194Trp and Arg399Gln polymorphisms may be differentially associated with skin cancer risk.
|
17355263 |
2007 |
|
rs1805009
|
|
|
0.020 |
GeneticVariation |
BEFREE |
MC1R gene sequencing identified in two NBCCS patients affected by multiple basal cell carcinomas a functional MC1R variant, D294H, previously shown to be associated with skin cancer risk.
|
18539553 |
2008 |
|
rs1042522
|
|
|
0.040 |
GeneticVariation |
BEFREE |
We evaluated the effect of MDM2 SNP309 and its interaction with the p53 Arg72Pro polymorphism on pigmentary phenotypes and skin cancer risk in a nested case-control study within the Nurses' Health Study (NHS) among 219 melanoma cases, 286 squamous cell carcinoma (SCC) cases, 300 basal cell carcinoma (BCC) cases, and 873 controls, and among controls from other studies.
|
18814047 |
2009 |
|
rs1131691014
|
|
|
0.040 |
GeneticVariation |
BEFREE |
We evaluated the effect of MDM2 SNP309 and its interaction with the p53 Arg72Pro polymorphism on pigmentary phenotypes and skin cancer risk in a nested case-control study within the Nurses' Health Study (NHS) among 219 melanoma cases, 286 squamous cell carcinoma (SCC) cases, 300 basal cell carcinoma (BCC) cases, and 873 controls, and among controls from other studies.
|
18814047 |
2009 |
|
rs878854066
|
|
|
0.040 |
GeneticVariation |
BEFREE |
We evaluated the effect of MDM2 SNP309 and its interaction with the p53 Arg72Pro polymorphism on pigmentary phenotypes and skin cancer risk in a nested case-control study within the Nurses' Health Study (NHS) among 219 melanoma cases, 286 squamous cell carcinoma (SCC) cases, 300 basal cell carcinoma (BCC) cases, and 873 controls, and among controls from other studies.
|
18814047 |
2009 |
|
rs1353702185
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We evaluated the effect of MDM2 SNP309 and its interaction with the p53 Arg72Pro polymorphism on pigmentary phenotypes and skin cancer risk in a nested case-control study within the Nurses' Health Study (NHS) among 219 melanoma cases, 286 squamous cell carcinoma (SCC) cases, 300 basal cell carcinoma (BCC) cases, and 873 controls, and among controls from other studies.
|
18814047 |
2009 |
|
rs41556519
|
|
|
0.010 |
GeneticVariation |
BEFREE |
However, there is marked clinical heterogeneity (including presence or absence of skin cancers or neurological degeneration) in these XPD/R683W patients, thus suggesting a contribution of the second allele.
|
19934020 |
2009 |
|
rs1042522
|
|
|
0.040 |
GeneticVariation |
BEFREE |
In conclusion, this meta-analysis suggests that the TP53 Arg72Pro polymorphism may have little involvement in skin cancer susceptibility.
|
20861852 |
2011 |