Source: CURATED ×
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs718314
rs718314
LOC105369705
0.840 GeneticVariation GWASCAT Sex specific associations in genome wide association analysis of renal cell carcinoma. 31231134

2019
dbSNP: rs718314
rs718314
LOC105369705
0.840 GeneticVariation GWASCAT Genome-wide association study identifies multiple risk loci for renal cell carcinoma. 28598434

2017
dbSNP: rs718314
rs718314
LOC105369705
0.840 GeneticVariation GWASDB We identified two common variants in linkage disequilibrium, rs718314 and rs1049380 (r(2) = 0.64, D ' = 0.84), in the inositol 1,4,5-triphosphate receptor, type 2 (ITPR2) gene on 12p11.23 as novel susceptibility loci for RCC (P = 8.89 × 10(-10) and P = 6.07 × 10(-9), respectively, in meta-analysis) with an allelic odds ratio of 1.19 [95% confidence interval (CI): 1.13-1.26] for rs718314 and 1.18 (95% CI: 1.12-1.25) for rs1049380. 22010048

2012
dbSNP: rs718314
rs718314
LOC105369705
0.840 GeneticVariation GWASCAT We identified two common variants in linkage disequilibrium, rs718314 and rs1049380 (r(2) = 0.64, D ' = 0.84), in the inositol 1,4,5-triphosphate receptor, type 2 (ITPR2) gene on 12p11.23 as novel susceptibility loci for RCC (P = 8.89 × 10(-10) and P = 6.07 × 10(-9), respectively, in meta-analysis) with an allelic odds ratio of 1.19 [95% confidence interval (CI): 1.13-1.26] for rs718314 and 1.18 (95% CI: 1.12-1.25) for rs1049380. 22010048

2012
dbSNP: rs7105934
rs7105934
LOC102724265
0.830 GeneticVariation GWASCAT Sex specific associations in genome wide association analysis of renal cell carcinoma. 31231134

2019
dbSNP: rs7579899
rs7579899
EPAS1
0.830 GeneticVariation GWASCAT Sex specific associations in genome wide association analysis of renal cell carcinoma. 31231134

2019
dbSNP: rs7105934
rs7105934
LOC102724265
0.830 GeneticVariation GWASCAT Genome-wide association study identifies multiple risk loci for renal cell carcinoma. 28598434

2017
dbSNP: rs7579899
rs7579899
EPAS1
0.830 GeneticVariation GWASCAT Genome-wide association study identifies multiple risk loci for renal cell carcinoma. 28598434

2017
dbSNP: rs7105934
rs7105934
LOC102724265
0.830 GeneticVariation GWASDB A genome-wide association study identifies a novel susceptibility locus for renal cell carcinoma on 12p11.23. 22010048

2012
dbSNP: rs7105934
rs7105934
LOC102724265
0.830 GeneticVariation GWASCAT Genome-wide association study of renal cell carcinoma identifies two susceptibility loci on 2p21 and 11q13.3. 21131975

2011
dbSNP: rs7105934
rs7105934
LOC102724265
0.830 GeneticVariation GWASDB Genome-wide association study of renal cell carcinoma identifies two susceptibility loci on 2p21 and 11q13.3. 21131975

2011
dbSNP: rs7579899
rs7579899
EPAS1
0.830 GeneticVariation GWASCAT Two correlated variants (r² = 0.99 in controls), rs11894252 (P = 1.8 × 10⁻⁸) and rs7579899 (P = 2.3 × 10⁻⁹), map to EPAS1 on 2p21, which encodes hypoxia-inducible-factor-2 alpha, a transcription factor previously implicated in RCC. 21131975

2011
dbSNP: rs7579899
rs7579899
EPAS1
0.830 GeneticVariation GWASDB Two correlated variants (r² = 0.99 in controls), rs11894252 (P = 1.8 × 10⁻⁸) and rs7579899 (P = 2.3 × 10⁻⁹), map to EPAS1 on 2p21, which encodes hypoxia-inducible-factor-2 alpha, a transcription factor previously implicated in RCC. 21131975

2011
dbSNP: rs1049380
rs1049380
ITPR2
0.820 GeneticVariation GWASCAT Sex specific associations in genome wide association analysis of renal cell carcinoma. 31231134

2019
dbSNP: rs1049380
rs1049380
ITPR2
0.820 GeneticVariation GWASCAT Genome-wide association study identifies multiple risk loci for renal cell carcinoma. 28598434

2017
dbSNP: rs1049380
rs1049380
ITPR2
0.820 GeneticVariation GWASDB We identified two common variants in linkage disequilibrium, rs718314 and rs1049380 (r(2) = 0.64, D ' = 0.84), in the inositol 1,4,5-triphosphate receptor, type 2 (ITPR2) gene on 12p11.23 as novel susceptibility loci for RCC (P = 8.89 × 10(-10) and P = 6.07 × 10(-9), respectively, in meta-analysis) with an allelic odds ratio of 1.19 [95% confidence interval (CI): 1.13-1.26] for rs718314 and 1.18 (95% CI: 1.12-1.25) for rs1049380. 22010048

2012
dbSNP: rs11894252
rs11894252
EPAS1
0.810 GeneticVariation GWASCAT Sex specific associations in genome wide association analysis of renal cell carcinoma. 31231134

2019
dbSNP: rs11894252
rs11894252
EPAS1
0.810 GeneticVariation GWASCAT Genome-wide association study identifies multiple risk loci for renal cell carcinoma. 28598434

2017
dbSNP: rs4765623
rs4765623
SCARB1
0.810 GeneticVariation GWASCAT Genome-wide association study identifies multiple risk loci for renal cell carcinoma. 28598434

2017
dbSNP: rs11894252
rs11894252
EPAS1
0.810 GeneticVariation GWASDB A genome-wide association study identifies a novel susceptibility locus for renal cell carcinoma on 12p11.23. 22010048

2012
dbSNP: rs11894252
rs11894252
EPAS1
0.810 GeneticVariation GWASDB Two correlated variants (r² = 0.99 in controls), rs11894252 (P = 1.8 × 10⁻⁸) and rs7579899 (P = 2.3 × 10⁻⁹), map to EPAS1 on 2p21, which encodes hypoxia-inducible-factor-2 alpha, a transcription factor previously implicated in RCC. 21131975

2011
dbSNP: rs4765623
rs4765623
SCARB1
0.810 GeneticVariation GWASDB Genome-wide association study of renal cell carcinoma identifies two susceptibility loci on 2p21 and 11q13.3. 21131975

2011
dbSNP: rs4765623
rs4765623
SCARB1
0.810 GeneticVariation GWASCAT Genome-wide association study of renal cell carcinoma identifies two susceptibility loci on 2p21 and 11q13.3. 21131975

2011
dbSNP: rs2121266
rs2121266
EPAS1
C 0.800 GeneticVariation GWASCAT Sex specific associations in genome wide association analysis of renal cell carcinoma. 31231134

2019
dbSNP: rs12105918
rs12105918
ZEB2
0.800 GeneticVariation GWASCAT Genome-wide association study identifies multiple risk loci for renal cell carcinoma. 28598434

2017