rs9939609
|
|
|
0.900 |
GeneticVariation |
BEFREE |
The minor allele (T) in rs9939609 was significantly higher (P=0.0001) in T2DM (31.25%) when compared with that of the control obese group (20%).
|
28603074 |
2017 |
rs9939609
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Variants (such as rs9939609) in the fat mass- and obesity-associated (FTO) gene have been associated with obesity, type 2 diabetes, some cancers, and alcohol consumption.
|
23771786 |
2013 |
rs9939609
|
|
|
0.900 |
GeneticVariation |
BEFREE |
This was a cross-sectional study of 236 patients with type 2 diabetes (age 60.0 ± 10.3 years; diabetes duration 12.7 ± 8.2 years; 53.4% females) who were genotyped for FTO rs9939609.
|
23689376 |
2013 |
rs9939609
|
|
|
0.900 |
GeneticVariation |
BEFREE |
We investigated the association between genetic variants in FTO (rs9939609) and near MC4R (rs17782313) with obesity- and type 2 diabetes (T2DM)-related traits in a longitudinal birth cohort of 2,151 healthy individuals from the Vellore birth cohort in South India.
|
22421923 |
2012 |
rs9939609
|
|
|
0.900 |
GeneticVariation |
BEFREE |
We investigated potential interactions between body mass index (BMI) and genotypes of human leukocyte antigen (HLA), TCF7L2-rs7903146, and FTO-rs9939609 in relation to the risk of latent autoimmune diabetes in adults (LADA) and type 2 diabetes.
|
31125083 |
2019 |
rs9939609
|
|
A |
0.900 |
GeneticVariation |
GWASCAT |
Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases.
|
22693455 |
2012 |
rs9939609
|
|
|
0.900 |
GeneticVariation |
GWASDB |
Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians.
|
22158537 |
2011 |
rs9939609
|
|
|
0.900 |
GeneticVariation |
BEFREE |
The increased fat mass in carriers of the A allele of rs9939609 of FTO is associated not only with increased risk of type 2 diabetes, but also with an increase in atherogenic lipid profile and myocardial infarction in these patients.
|
20031593 |
2009 |
rs9939609
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Recent genome-wide association studies have showed that common variant (rs9939609) in fat mass and obesity associated (FTO) gene was significantly associated with type 2 diabetes through an effect on human body mass index/obesity.
|
22311015 |
2012 |
rs9939609
|
|
|
0.900 |
GeneticVariation |
GWASDB |
Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes.
|
17463249 |
2007 |
rs9939609
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Previous genome-wide association studies for type 2 diabetes susceptibility genes have confirmed that a common variant, rs9939609, in the fat mass and obesity associated (FTO) gene region is associated with body mass index (BMI) in European children and adults.
|
20598163 |
2010 |
rs9939609
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Using MGA, some common gene variants were found to have little (<5%) but significant impact on the heritability of T2D related QTs [KCNJ11 (rs5219), p=0.004]; [IGF2BP2 (rs4402960), p=0.02]; [SLC30A8 (rs13266634), p=0.05]; [CAPN10 (rs2975760), p=0.031]; [FTO (rs8050136), p=0.023]; [FTO (rs9939609), p=0.018] and [SLC30A8 (rs13266634), p=0.05].
|
24993573 |
2014 |
rs9939609
|
|
|
0.900 |
GeneticVariation |
BEFREE |
However, no significant association was found between genetics and risk of type 2 diabetes after control of potential confounders (at least for BMI) either for rs9939609 (fixed effect OR=1.05, 95% CI=0.97,1.13) or for rs8050136 polymorphism (fixed effect OR =1.07, 95%CI: 0.99, 1.16).
|
20337217 |
2009 |
rs9939609
|
|
|
0.900 |
GeneticVariation |
BEFREE |
A total of 236 patients with type 2 diabetes (age: 60.0 ± 10.3 years; diabetes duration: 12.7 ± 8.2 years; 53.4% women) were genotyped for the FTO rs7204609 and rs9939609 polymorphisms (ABI PRISM 7000 Real-Time PCR System).
|
21741858 |
2012 |
rs9939609
|
|
|
0.900 |
GeneticVariation |
BEFREE |
This study aimed to investigate the association of FTO rs9939609 and MC4R rs17782313 with anthropometric indexes, BP, and type 2 diabetes mellitus among hypertensive patients.
|
23849767 |
2013 |
rs9939609
|
|
|
0.900 |
GeneticVariation |
BEFREE |
The meta-analysis revealed a highly significant association for rs9939609 with both type 2 diabetes (OR 1.13; P = 4.5 × 10(-8)) and the risk to develop incident type 2 diabetes (OR 1.16; P = 3.2 × 10(-8)).
|
21398525 |
2011 |
rs9939609
|
|
|
0.900 |
GeneticVariation |
BEFREE |
None of the variants including previously reported intron 1 variants (rs1421085, rs8050136, rs9939609 and rs9930506) showed body mass index (BMI)-dependent/independent association with type 2 diabetes.
|
21814223 |
2011 |
rs9939609
|
|
|
0.900 |
GeneticVariation |
BEFREE |
The fat mass- and obesity-associated gene rs9939609 SNP is strongly associated with risk of obesity and newly diagnosed T2D in the Chinese population.
|
20186840 |
2010 |
rs9939609
|
|
|
0.900 |
GeneticVariation |
GWASDB |
Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India.
|
23300278 |
2013 |
rs9939609
|
|
|
0.900 |
GeneticVariation |
BEFREE |
The fat mass and obesity-associated gene (FTO) rs9939609 and peroxisome proliferator-activated receptor gamma 2 gene (PPARG2) rs1801282 polymorphisms are type 2 diabetes mellitus susceptibility gene variants associated with obesity.
|
24969838 |
2014 |
rs9939609
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Recently an association was demonstrated between the single nucleotide polymorphism (SNP), rs9939609, within the FTO locus and obesity as a consequence of a genome wide association (GWA) study of type 2 diabetes in adults.
|
18335027 |
2008 |
rs9939609
|
|
|
0.900 |
GeneticVariation |
BEFREE |
The variant rs9939609 of the FTO gene was associated with T2DM in Palestine.
|
30170548 |
2018 |
rs9939609
|
|
A |
0.900 |
GeneticVariation |
GWASDB |
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.
|
17554300 |
2007 |
rs9939609
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Our data suggest that the associations between <i>FTO</i> rs9939609, rs8050136 and T2DM are region-related, and the two single-nucleotide polymorphisms contribute to an increased risk of T2DM.
|
28208657 |
2017 |
rs9939609
|
|
|
0.900 |
GeneticVariation |
BEFREE |
The meta-analysis of PPARγ2 (rs1801282) showed population-specific </span>association for T2D susceptibility as oppo</span>sed to FTO (rs9939609) which showed no difference in population effect toward T2D susceptibility.
|
26243686 |
2016 |