rs587777736
|
|
G |
0.700 |
GeneticVariation |
CLINVAR |
Mutations in NOTCH1 cause Adams-Oliver syndrome.
|
25132448 |
2014 |
rs757075712
|
|
T |
0.700 |
GeneticVariation |
CLINVAR |
|
|
|
rs1217691063
|
|
|
0.070 |
GeneticVariation |
BEFREE |
MTHFR C677T and A1298C were not associated with preeclampsia (OR, 1.06; 95% CI, 0.97-1.16 and OR, 1.16; 95% CI, 0.97-1.39, respectively), and C677T was not associated with placental abruption (OR, 1.03; 95% CI, 0.87-1.21), intrauterine growth retardation (OR, 1.02; 95% CI, 0.90-1.15), or congenital heart disease (OR, 1.05; 95% CI, 0.89-1.25).
|
30474229 |
2019 |
rs1217691063
|
|
|
0.070 |
GeneticVariation |
BEFREE |
Our aim in this study was to investigate the association between elevated homocysteine levels and the two MTHFR polymorphisms, C677T and A1298C, with several pregnancy complications such as recurrent pregnancy loss, preeclampsia, placental abruption and intrauterine growth retardation.
|
21577095 |
2011 |
rs1217691063
|
|
|
0.070 |
GeneticVariation |
BEFREE |
The following number of related studies were found: studies evaluating relationships between factor V Leiden mutation and IUGR, 12 case-control and four cohort; between PT mutation and IUGR, 11 case-control and 0 cohort; and between MTHFR C677T homozygosity and IUGR, 10 case-control and two cohort.
|
19461414 |
2009 |
rs1217691063
|
|
|
0.070 |
GeneticVariation |
BEFREE |
No association was found in this study between intrauterine growth restriction with abnormal umbilical blood flow and thrombophilic polymorphisms or methylenetetrahydrofolate reductase C677T.
|
15075078 |
2004 |
rs1217691063
|
|
|
0.070 |
GeneticVariation |
BEFREE |
Newborns who were homozygous for the MTHFR C677T variant had a decreased risk of intrauterine growth restriction (odds ratio after adjustment for mother's genotype and other confounders, 0.52 [95 percent confidence interval, 0.29 to 0.94]).
|
12097536 |
2002 |
rs1217691063
|
|
|
0.070 |
GeneticVariation |
BEFREE |
Combined heterozygosity for methylenetetrahydrofolate reductase (MTHFR) mutations C677T and A1298C is associated with abruptio placentae but not with intrauterine growth restriction.
|
11451544 |
2001 |
rs1217691063
|
|
|
0.070 |
GeneticVariation |
BEFREE |
This study was undertaken to investigate whether the cytosine-to-thymine substitution at nucleotide 677 (C677T) in the 5, 10-methylenetetrahydrofolate reductase gene is a risk factor for placental vasculopathy (abruptio placentae or placental infarction with fetal growth restriction).
|
10819868 |
2000 |
rs397507444
|
|
|
0.030 |
GeneticVariation |
BEFREE |
MTHFR C677T and A1298C were not associated with preeclampsia (OR, 1.06; 95% CI, 0.97-1.16 and OR, 1.16; 95% CI, 0.97-1.39, respectively), and C677T was not associated with placental abruption (OR, 1.03; 95% CI, 0.87-1.21), intrauterine growth retardation (OR, 1.02; 95% CI, 0.90-1.15), or congenital heart disease (OR, 1.05; 95% CI, 0.89-1.25).
|
30474229 |
2019 |
rs397507444
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Our aim in this study was to investigate the association between elevated homocysteine levels and the two MTHFR polymorphisms, C677T and A1298C, with several pregnancy complications such as recurrent pregnancy loss, preeclampsia, placental abruption and intrauterine growth retardation.
|
21577095 |
2011 |
rs1188383936
|
|
|
0.030 |
GeneticVariation |
BEFREE |
The following number of related studies were found: studies evaluating relationships between factor V Leiden mutation and IUGR, 12 case-control and four cohort; between PT mutation and IUGR, 11 case-control and 0 cohort; and between MTHFR C677T homozygosity and IUGR, 10 case-control and two cohort.
|
19461414 |
2009 |
rs1188383936
|
|
|
0.030 |
GeneticVariation |
BEFREE |
No association was found in this study between intrauterine growth restriction with abnormal umbilical blood flow and thrombophilic polymorphisms or methylenetetrahydrofolate reductase C677T.
|
15075078 |
2004 |
rs1188383936
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Newborns who were homozygous for the MTHFR C677T variant had a decreased risk of intrauterine growth restriction (odds ratio after adjustment for mother's genotype and other confounders, 0.52 [95 percent confidence interval, 0.29 to 0.94]).
|
12097536 |
2002 |
rs397507444
|
|
|
0.030 |
GeneticVariation |
BEFREE |
A significant association could be demonstrated between mutation A1298C and both abruptio placentae and IUGR.
|
11451544 |
2001 |
rs1799963
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A combination of alleles G of rs1799963, A of rs6046, and G of rs1800790 (OR = 0.31) reduces the risk of FGR.
|
28544373 |
2017 |
rs1800790
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A combination of alleles G of rs1799963, A of rs6046, and G of rs1800790 (OR = 0.31) reduces the risk of FGR.
|
28544373 |
2017 |
rs6046
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Polymorphism rs6046 of the FVII gene is associated with the development of FGR.
|
28544373 |
2017 |
rs121918474
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We found that protein S K196E mutation was identified in 4 out of 233 patients with recurrent miscarriage and in 2 out of 114 patients with FGR and/or IUFD.
|
24613695 |
2014 |
rs318240750
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We identified the novel c.836G>[G;T] (p.Arg279Leu) mutation in a familial case of intrauterine growth retardation (IUGR) with RSS phenotype and no evidence of IMAGe.
|
24065356 |
2013 |
rs1253103806
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Only the second compound heterozygous IGF1R mutations to be identified, the p.E121K/E234K variant is the cause of intrauterine growth retardation and the most severe postnatal growth failure described to date in a patient with IGF1R defects.
|
22130793 |
2012 |
rs187980012
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We identified a family bearing a new heterozygous missense mutation at the L2 domain of IGF-IR (R431L) through an 8-year-old girl and her mother, both born with intrauterine growth retardation.
|
22309212 |
2012 |
rs1799983
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The results suggested a lack of association between the Glu298Asp gene polymorphism and pre-eclampsia without FGR in the Turkish population.
|
20598027 |
2010 |
rs2536512
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Association of extracellular superoxide dismutase (SOD3) Ala40Thr gene polymorphism with pre-eclampsia complicated by severe fetal growth restriction.
|
19108943 |
2009 |
rs28937590
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A homozygous point mutation (232A-->G) has been found as the genetic etiology for fetal growth retardation, amino aciduria, cholestasis, iron overload, lactic acidosis, and early death (GRACILE) syndrome (MIM 603358).
|
18386115 |
2008 |