|
rs1800872
|
|
|
0.010 |
GeneticVariation |
BEFREE |
However, the duration of fever, white blood cell (WBC) count, C-reactive protein (CRP), neutrophils, and lymphocytes and monocytes of virus-induced encephalitis patients with IL-4 rs2227288 and IL-10 rs1800872 all displayed significant differences (all P<0.05).
|
28935853 |
2017 |
|
rs2227288
|
|
|
0.010 |
GeneticVariation |
BEFREE |
However, the duration of fever, white blood cell (WBC) count, C-reactive protein (CRP), neutrophils, and lymphocytes and monocytes of virus-induced encephalitis patients with IL-4 rs2227288 and IL-10 rs1800872 all displayed significant differences (all P<0.05).
|
28935853 |
2017 |
|
rs35829419
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A 15-year-old patient with double heterozygosity for the mutations 1129G>A and 928G>A in MVK gene, heterozygosity for the mutation 2107C>A in CIAS1 gene and hyper-IgD syndrome phenotype, has been treated with anakinra with a reduction of 50% in the number of fever episodes per month, a reduction of 33% in the days of fever for each attack and normal blood tests in the intercritical phase.
|
28638818 |
2017 |
|
rs104895358
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Hyper-IgD and periodic fever syndrome (HIDS) due to compound heterozygosity for G336S and V377I in a 44-year-old patient with a 27-year history of fever.
|
27899390 |
2016 |
|
rs1051266
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our findings suggested that the risk of NTDs was potentially influenced by a gene-environment interaction between maternal SLC19A1 rs1051266 GG/GA genotype and first trimester fever.
|
24917213 |
2015 |
|
rs11568658
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The ABCC4 single nucleotide polymorphism rs11568658 was associated with misoprostol-induced fever.
|
26122863 |
2015 |
|
rs1204135596
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A rare, c.1955G>A, p.Arg652His MEFV gene variant was identified at negligible levels in an early peripheral blood DNA sample, but affected 46 % of the MEFV alleles and was restricted to JAK2-positive, polymorphonuclear and CD3-depleted mononunuclear DNA samples obtained 4 years later, when the patient experienced fever bouts.
|
26123310 |
2015 |
|
rs766778566
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A rare, c.1955G>A, p.Arg652His MEFV gene variant was identified at negligible levels in an early peripheral blood DNA sample, but affected 46 % of the MEFV alleles and was restricted to JAK2-positive, polymorphonuclear and CD3-depleted mononunuclear DNA samples obtained 4 years later, when the patient experienced fever bouts.
|
26123310 |
2015 |
|
rs766778566
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A rare, c.1955G>A, p.Arg652His MEFV gene variant was identified at negligible levels in an early peripheral blood DNA sample, but affected 46 % of the MEFV alleles and was restricted to JAK2-positive, polymorphonuclear and CD3-depleted mononunuclear DNA samples obtained 4 years later, when the patient experienced fever bouts.
|
26123310 |
2015 |
|
rs7805622
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Through genome-wide association study (GWAS) of evoked endotoxemia (lipopolysaccharide (LPS) 1 ng/kg IV) in healthy subjects of European ancestry we discovered a locus on chr7p11.2 significantly associated with the peak febrile response to LPS (top single nucleotide polymorphism (SNP) rs7805622, P = 2.4 × 10(-12)), as well as with temperature fluctuation over time.
|
25416278 |
2015 |
|
rs1800692
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In patients with TRAPS, rs1800692 T/T homozygotes were excessively rare (p<10(-4)) and TRAPS-like patients with this genotype experienced less fever.
|
23505244 |
2014 |
|
rs1800795
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We evaluated the role of single nucleotide polymorphisms for five genes: bactericidal permeability increasing protein (BPI; rs5743507), lipopolysaccharide-binding protein (LBP; rs2232618), toll-like receptor 4 (TLR4; rs4986790), heat shock protein 70 (HSP 70; rs2227956), and interleukin 6 (IL-6; rs1800795) in 598 children aged 0 to 19 years that were admitted to a paediatric intensive care unit with fever, systemic inflammatory response syndrome, sepsis, severe sepsis, septic shock, or multiple organ dysfunction syndrome.
|
24383711 |
2014 |
|
rs2227956
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We evaluated the role of single nucleotide polymorphisms for five genes: bactericidal permeability increasing protein (BPI; rs5743507), lipopolysaccharide-binding protein (LBP; rs2232618), toll-like receptor 4 (TLR4; rs4986790), heat shock protein 70 (HSP 70; rs2227956), and interleukin 6 (IL-6; rs1800795) in 598 children aged 0 to 19 years that were admitted to a paediatric intensive care unit with fever, systemic inflammatory response syndrome, sepsis, severe sepsis, septic shock, or multiple organ dysfunction syndrome.
|
24383711 |
2014 |
|
rs2232618
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We evaluated the role of single nucleotide polymorphisms for five genes: bactericidal permeability increasing protein (BPI; rs5743507), lipopolysaccharide-binding protein (LBP; rs2232618), toll-like receptor 4 (TLR4; rs4986790), heat shock protein 70 (HSP 70; rs2227956), and interleukin 6 (IL-6; rs1800795) in 598 children aged 0 to 19 years that were admitted to a paediatric intensive care unit with fever, systemic inflammatory response syndrome, sepsis, severe sepsis, septic shock, or multiple organ dysfunction syndrome.
|
24383711 |
2014 |
|
rs4986790
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We evaluated the role of single nucleotide polymorphisms for five genes: bactericidal permeability increasing protein (BPI; rs5743507), lipopolysaccharide-binding protein (LBP; rs2232618), toll-like receptor 4 (TLR4; rs4986790), heat shock protein 70 (HSP 70; rs2227956), and interleukin 6 (IL-6; rs1800795) in 598 children aged 0 to 19 years that were admitted to a paediatric intensive care unit with fever, systemic inflammatory response syndrome, sepsis, severe sepsis, septic shock, or multiple organ dysfunction syndrome.
|
24383711 |
2014 |
|
rs5743507
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We evaluated the role of single nucleotide polymorphisms for five genes: bactericidal permeability increasing protein (BPI; rs5743507), lipopolysaccharide-binding protein (LBP; rs2232618), toll-like receptor 4 (TLR4; rs4986790), heat shock protein 70 (HSP 70; rs2227956), and interleukin 6 (IL-6; rs1800795) in 598 children aged 0 to 19 years that were admitted to a paediatric intensive care unit with fever, systemic inflammatory response syndrome, sepsis, severe sepsis, septic shock, or multiple organ dysfunction syndrome.
|
24383711 |
2014 |
|
rs104895271
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The D12E substitution has been described only once to date, in a 4-year-old boy with fever.
|
23322460 |
2013 |
|
rs11575933
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This explains the higher susceptibility of the enzymatic activity of MDTCS-P475S to reaction environments such as denaturants and high temperature.
|
23621748 |
2013 |
|
rs1424748509
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Reported TNFRSF1A gene mutations in these nine index patients were C70S, T61I, C70G, C30Y, C30R, N101K, and N25D.Fever (100 %) was seen in all 23 cases.
|
22918594 |
2013 |
|
rs3804100
|
|
|
0.010 |
GeneticVariation |
BEFREE |
As the inflammatory responses in ALN patients are more severe than those in APN patients (higher CRP levels, longer duration of fever after antibiotic treatment), these findings suggest that the genetic variant in TLR-2 (rs3804100, T1350C) may protect the host from severe urinary tract infections as ALN.
|
23484049 |
2013 |
|
rs3811047
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Single nucleotide polymorphism (SNP) of IL-1F7 gene (rs3811047) was analyzed in 184 unrelated Chinese Han patients with RA and 184 healthy controls by ligase detection reaction based on high temperature ligase detection reactions polymerase chain reaction (LDR-PCR).
|
23171316 |
2013 |
|
rs3832879
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Each patient underwent evaluation of serum FGF23 levels and FGF23 genotype: the frequency of the c.212-37insC (rs3832879) polymorphism in intron 1 was examined and compared with sex, age at disease onset, fever duration, laboratory data, and occurrence of CaA.
|
24168888 |
2013 |
|
rs41550816
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Evaluation of a recombinant double mutant of staphylococcal enterotoxin B (SEB-H32Q/K173E) with enhanced antitumor activity effects and decreased pyrexia.
|
23405232 |
2013 |
|
rs747753882
|
|
|
0.010 |
GeneticVariation |
BEFREE |
As the inflammatory responses in ALN patients are more severe than those in APN patients (higher CRP levels, longer duration of fever after antibiotic treatment), these findings suggest that the genetic variant in TLR-2 (rs3804100, T1350C) may protect the host from severe urinary tract infections as ALN.
|
23484049 |
2013 |
|
rs755789256
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Evaluation of a recombinant double mutant of staphylococcal enterotoxin B (SEB-H32Q/K173E) with enhanced antitumor activity effects and decreased pyrexia.
|
23405232 |
2013 |