|
rs6068020
|
|
|
0.800 |
GeneticVariation |
GWASDB |
Genome-wide study of single-nucleotide polymorphisms associated with azoospermia and severe oligozoospermia.
|
19478329 |
2010 |
|
rs6068020
|
|
|
0.800 |
GeneticVariation |
GWASCAT |
Genome-wide study of single-nucleotide polymorphisms associated with azoospermia and severe oligozoospermia.
|
19478329 |
2010 |
|
rs9814870
|
|
|
0.800 |
GeneticVariation |
GWASCAT |
Genome-wide study of single-nucleotide polymorphisms associated with azoospermia and severe oligozoospermia.
|
19478329 |
2010 |
|
rs9814870
|
|
|
0.800 |
GeneticVariation |
GWASDB |
Genome-wide study of single-nucleotide polymorphisms associated with azoospermia and severe oligozoospermia.
|
19478329 |
2010 |
|
rs10966811
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In this study, we investigated whether the rs10966811 (located in an intergenic region between the TUSC1 and IZUMO3 genes) and rs10129954 (located in the DPF3 gene) SNPs, previously related to family size, are associated with male infertility.
|
28975488 |
2018 |
|
rs12097821
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The results suggested that rs2477686, rs6080550, and rs10842262 were significantly associated with male infertility, especially with NOA, while rs12097821 was only found to be associated with total male infertility.
|
30863997 |
2019 |
|
rs1259503
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Moreover, we could not find any differences in the variants rs7896741 and rs1259503, which showed no risk of male infertility, whether normal or abnormal.
|
27806320 |
2016 |
|
rs6476866
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A total of 136 subfertile men and 456 healthy fertile men were recruited. rs6476866 in SLC1A1 (P = 1.919E-4, OR = 0.5905, 95% CI: 0.447-0.78) and rs10129954 in DPF3 (P = 0.0023, OR = 2.199, 95% CI: 1.311-3.689) were strongly associated with idiopathic male infertility.
|
27232852 |
2018 |
|
rs724078
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Are the four candidate loci (rs7867029, rs7174015, rs12870438 and rs724078) for human male fertility traits, identified in a genome-wide association study (GWAS) of a Hutterite population in the USA, associated with male infertility in a Japanese population?
|
25908656 |
2015 |
|
rs727428
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Also, genotype frequencies, allele frequency, and haplotype were all analyzed in both groups.There were statistical differences in A allele frequency (P = .017) and GA genotype frequency (P = .016) of SHBG gene rs6259 locus and in CC genotype frequency of SHBG gene rs727428 locus (P = .034) between the 2 groups.Male infertility is associated with GA genotype and A allele of rs6259 locus, as well as CC genotype of rs727428 locus in SHBG gene.
|
28796064 |
2017 |
|
rs1045642
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Association of the MDR1 (ABCB1) gene 3435C>T polymorphism with male infertility.
|
19815951 |
2010 |
|
rs2066853
|
|
|
0.040 |
GeneticVariation |
BEFREE |
To examine whether Arg554Lys polymorphism in the gene for aryl hydrocarbon receptor (AHR) and/or Pro185Ala polymorphism in the gene for aryl hydrocarbon receptor repressor (AHRR) constitutes a susceptibility locus for dioxin-related male infertility.
|
15474075 |
2004 |
|
rs2066853
|
|
|
0.040 |
GeneticVariation |
BEFREE |
The pooled results showed that there was no significant association between <i>AHR</i> rs2066853</span> gene polymorphism and male infertility risk (A vs. G: OR = 1.08, 95% CI = 0.83-1.39; AA vs. GG: OR = 1.16, 95% CI = 0.65-2.04; AA vs. GA + GG: OR = 1.17, 95% CI = 0.66-2.07; AA + GA vs. GG: OR = 0.99, 95% CI = 0.85-1.15).
|
31662023 |
2019 |
|
rs2066853
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Homozygosity for the rs2066853 A allele and rs2282885 C allele decreases and increases the risk of developing male infertility, respectively.
|
23703535 |
2013 |
|
rs2066853
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Subgroup analysis by study population revealed there was no association between AhR Arg554Lys polymorphism and susceptibility to male infertility in Asian population (G versus A, OR (95%CI) = 1.099 (0.940-1.286); GG vs AA, OR (95%CI) = 0.982 (0.781-1.235); GA versus AA, OR (95%CI) = 1.220 (0.726-2.052); GG + GA vs AA, OR (95%CI) = 1.221 (0.740-1.982); GG versus GA + AA, OR (95%CI) = 1.087 (0.919-1.286)).
|
29427904 |
2018 |
|
rs2282885
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Homozygosity for the rs2066853 A allele and rs2282885 C allele decreases and increases the risk of developing male infertility, respectively.
|
23703535 |
2013 |
|
rs2292596
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The Pro185Ala polymorphism in AHRR may constitute a susceptibility locus for dioxin-related male infertility.
|
15474075 |
2004 |
|
rs2292596
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We found that polymorphism rs2292596 (Pro185Ala) was statistically significantly associated with the risk of male infertility.
|
30506768 |
2019 |
|
rs116298211
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Homozygous missense mutation L673P in adenylate kinase 7 (AK7) leads to primary male infertility and multiple morphological anomalies of the flagella but not to primary ciliary dyskinesia.
|
29365104 |
2018 |
|
rs1262199907
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To this aim, we selected four AR missense mutations associated with isolated male infertility (L547F and two novel mutations A474V and S650G) or partial AIS (Y571H).
|
17970778 |
2008 |
|
rs139524801
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To this aim, we selected four AR missense mutations associated with isolated male infertility (L547F and two novel mutations A474V and S650G) or partial AIS (Y571H).
|
17970778 |
2008 |
|
rs141425171
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A novel mutation (N233K) in the transactivating domain and the N756S mutation in the ligand binding domain of the androgen receptor gene are associated with male infertility.
|
11422119 |
2001 |
|
rs200390780
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To this aim, we selected four AR missense mutations associated with isolated male infertility (L547F and two novel mutations A474V and S650G) or partial AIS (Y571H).
|
17970778 |
2008 |
|
rs952566855
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In addition, the homozygous variant genotype GG of RAG1 rs2227973 (A>G, K820R) was associated with a significantly increased risk of male infertility (adjusted OR, 1.44; 95% CI, 1.01-2.04).
|
23630330 |
2013 |
|
rs140027779
|
|
|
0.010 |
GeneticVariation |
BEFREE |
No association of the A260G and A386G DAZL single nucleotide polymorphisms with male infertility in a Caucasian population.
|
15520024 |
2004 |