|
rs1799983
|
|
|
0.100 |
GeneticVariation |
BEFREE |
GG genotype of the Glu298Asp variant slowed the ESRD progression in ADPKD, while a allele carriers of the 4b/a variant increased the risk of ESRD.
|
24995932 |
2014 |
|
rs1799983
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Impact of nitric oxide synthase Glu298Asp polymorphism on the development of end-stage renal disease in type 2 diabetic Egyptian patients.
|
21854353 |
2011 |
|
rs1799983
|
|
|
0.100 |
GeneticVariation |
BEFREE |
In conclusion, the frequent Glu298Asp polymorphism of ENOS is associated with a 5 year lower mean age at ESRD in this subset of ADPKD males.
|
11823442 |
2002 |
|
rs1799983
|
|
|
0.100 |
GeneticVariation |
BEFREE |
In addition, a mutation, Glu298Asp, in exon 7 of NOS3 and a 27 bp variable number tandem repeat (VNTR) marker in intron 4 of NOS3 were evaluated in the sibling pairs and in an additional 92 unrelated African-Americans with type 2 diabetes mellitus-associated ESRD (singletons).
|
11071967 |
2000 |
|
rs1799983
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The results suggested that the Glu298Asp polymorphism of NOS3 gene is associated with the onset age of ESRD.
|
18815450 |
2008 |
|
rs699
|
|
|
0.090 |
GeneticVariation |
BEFREE |
There was no association between age at onset of ESRD and either M235T or A1166C polymorphism.
|
11136175 |
2001 |
|
rs699
|
|
|
0.090 |
GeneticVariation |
BEFREE |
We conclude that heterozygous substitutions at the AGT M235T and REN A/G(I8-83) loci correlate significantly with ESRD in a north Indian population.
|
25660845 |
2015 |
|
rs699
|
|
|
0.090 |
GeneticVariation |
BEFREE |
Two hundred and forty-six end-stage renal disease (ESRD) patients on peritoneal dialysis and 183 control subjects, all of Chinese origin, were genotyped for the ACE insertion/deletion (I/D) and the AGT M235T gene polymorphisms.
|
12675870 |
2003 |
|
rs699
|
|
|
0.090 |
GeneticVariation |
BEFREE |
The results of this study suggest that ACE gene insertion/deletion and angiotensinogen M235T polymorphisms contribute to the increased risk for the development of CRF, but the magnitude of the effect within subsets of patients with specific etiologies of CRF must be evaluated further.
|
10916074 |
2000 |
|
rs699
|
|
|
0.090 |
GeneticVariation |
BEFREE |
Furthermore, there was no a markedly positive association between AGT M235T gene polymorphism and ESRD susceptibility in overall populations, Asians and Africans.
|
23065231 |
2013 |
|
rs699
|
|
|
0.090 |
GeneticVariation |
BEFREE |
There was no interaction between age of onset of ESRF and either the angiotensinogen M235T allele or angiotensin 1 receptor A1166C polymorphism.
|
9291178 |
1997 |
|
rs699
|
|
|
0.090 |
GeneticVariation |
BEFREE |
This study was designed to evaluate the angiotensin-converting enzyme insertion/deletion (ACE-I/D), angiotensinogen (AGT) M235T, and angiotensin II receptor type 1 (ATR1) A1166C and type 2 (ATR2) C3123A gene polymorphisms as risk factors for progression to ESRD in patients with VUR.Methods.
|
19288324 |
2009 |
|
rs699
|
|
|
0.090 |
GeneticVariation |
BEFREE |
We studied retrospectively the role of angiotensinogen (AGT) M235T, angiotensin converting enzyme (ACE) insertion/deletion (I/D), angiotensin II type 1 receptor (AT1R) A1166C, aldosterone syntase (CYP11B2) -344C/T and intron 2 W/C polymorphisms in conjunction with clinical and biochemical covariables on the rate of progression of renal insufficiency in a group of patients with ESRD of various etiologies.
|
12832734 |
2003 |
|
rs699
|
|
|
0.090 |
GeneticVariation |
BEFREE |
There were no differences in the prevalence of hypertension and the ages at the ESRD in relation to the AGT M235T and ATR A1166C polymorphisms.
|
12950120 |
2003 |
|
rs1267969615
|
|
|
0.060 |
GeneticVariation |
BEFREE |
There was no association between age at onset of ESRD and either M235T or A1166C polymorphism.
|
11136175 |
2001 |
|
rs1267969615
|
|
|
0.060 |
GeneticVariation |
BEFREE |
This study was designed to evaluate the angiotensin-converting enzyme insertion/deletion (ACE-I/D), angiotensinogen (AGT) M235T, and angiotensin II receptor type 1 (ATR1) A1166C and type 2 (ATR2) C3123A gene polymorphisms as risk factors for progression to ESRD in patients with VUR.Methods.
|
19288324 |
2009 |
|
rs1267969615
|
|
|
0.060 |
GeneticVariation |
BEFREE |
There was no interaction between age of onset of ESRF and either the angiotensinogen M235T allele or angiotensin 1 receptor A1166C polymorphism.
|
9291178 |
1997 |
|
rs1267969615
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Two hundred and forty-six end-stage renal disease (ESRD) patients on peritoneal dialysis and 183 control subjects, all of Chinese origin, were genotyped for the ACE insertion/deletion (I/D) and the AGT M235T gene polymorphisms.
|
12675870 |
2003 |
|
rs1267969615
|
|
|
0.060 |
GeneticVariation |
BEFREE |
We studied retrospectively the role of angiotensinogen (AGT) M235T, angiotensin converting enzyme (ACE) insertion/deletion (I/D), angiotensin II type 1 receptor (AT1R) A1166C, aldosterone syntase (CYP11B2) -344C/T and intron 2 W/C polymorphisms in conjunction with clinical and biochemical covariables on the rate of progression of renal insufficiency in a group of patients with ESRD of various etiologies.
|
12832734 |
2003 |
|
rs1267969615
|
|
|
0.060 |
GeneticVariation |
BEFREE |
The results of this study suggest that ACE gene insertion/deletion and angiotensinogen M235T polymorphisms contribute to the increased risk for the development of CRF, but the magnitude of the effect within subsets of patients with specific etiologies of CRF must be evaluated further.
|
10916074 |
2000 |
|
rs1801282
|
|
|
0.050 |
GeneticVariation |
BEFREE |
The aim of this study was to clarify whether the PPAR-gamma 161C/T and PPAR-gamma2 Pro12Ala single-nucleotide polymorphisms (SNPs) influence the inter-individual variance of inflammation and mortality in ESRD patients.
|
16115480 |
2005 |
|
rs1801282
|
|
|
0.050 |
GeneticVariation |
BEFREE |
Cox's proportional hazard regression showed that both Pro12Ala and C161T polymorphisms were significant predictors of mortality in ESRD patients with DM (Pro12Ala: GG versus other genotypes, hazard ratio [HR] <0.01; P < 0.001; for C161T, CC versus TT genotypes, HR 2.86; P < 0.001; CT versus TT genotypes, HR 1.93; P < 0.001).
|
25784779 |
2015 |
|
rs1801282
|
|
|
0.050 |
GeneticVariation |
BEFREE |
Future research should focus on the effect of Pro12Ala polymorphism on ESRD and gathering data of Africans.
|
22619290 |
2012 |
|
rs1801282
|
|
|
0.050 |
GeneticVariation |
BEFREE |
We detected significant interactions between SNPs including PPAR-γ Pro12Ala, C161T, and GPX1 regarding the risk of ESRD.Conclusion.
|
26881045 |
2016 |
|
rs1801282
|
|
|
0.050 |
GeneticVariation |
BEFREE |
The PPAR gamma 2 Pro12Ala variant predicts ESRD and mortality in patients with type 1 diabetes and diabetic nephropathy.
|
18467141 |
2008 |