Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs369203092
rs369203092
ATM
0.700 GeneticVariation UNIPROT

dbSNP: rs371713984
rs371713984
ATM
0.700 GeneticVariation UNIPROT

dbSNP: rs567060474
rs567060474
0.700 GeneticVariation UNIPROT

dbSNP: rs587781894
rs587781894
0.700 GeneticVariation UNIPROT

dbSNP: rs876660821
rs876660821
0.010 GeneticVariation BEFREE DNA sequencing of p53 exons 5 to 9 revealed a codon 179 His to Gln change in one of the ELISA-positive, progressive B-CLL but failed to reveal any mutations in 4 other ELISA-positive, progressive B-CLL. 8056442

1994

dbSNP: rs11554290
rs11554290
0.710 GeneticVariation BEFREE Altogether, one diffuse large B-cell lymphoma and one B-cell chronic lymphocytic leukemia (B-CLL) harbored a mutation (G12S and G12A, respectively) in the K-ras gene, and one B-CLL harbored a mutation (Q61R) in the N-ras gene. 9139869

1997

dbSNP: rs1057519695
rs1057519695
0.010 GeneticVariation BEFREE Altogether, one diffuse large B-cell lymphoma and one B-cell chronic lymphocytic leukemia (B-CLL) harbored a mutation (G12S and G12A, respectively) in the K-ras gene, and one B-CLL harbored a mutation (Q61R) in the N-ras gene. 9139869

1997

dbSNP: rs1057519834
rs1057519834
0.010 GeneticVariation BEFREE Altogether, one diffuse large B-cell lymphoma and one B-cell chronic lymphocytic leukemia (B-CLL) harbored a mutation (G12S and G12A, respectively) in the K-ras gene, and one B-CLL harbored a mutation (Q61R) in the N-ras gene. 9139869

1997

dbSNP: rs121913237
rs121913237
0.010 GeneticVariation BEFREE Altogether, one diffuse large B-cell lymphoma and one B-cell chronic lymphocytic leukemia (B-CLL) harbored a mutation (G12S and G12A, respectively) in the K-ras gene, and one B-CLL harbored a mutation (Q61R) in the N-ras gene. 9139869

1997

dbSNP: rs121913240
rs121913240
0.010 GeneticVariation BEFREE Altogether, one diffuse large B-cell lymphoma and one B-cell chronic lymphocytic leukemia (B-CLL) harbored a mutation (G12S and G12A, respectively) in the K-ras gene, and one B-CLL harbored a mutation (Q61R) in the N-ras gene. 9139869

1997

dbSNP: rs121913250
rs121913250
0.010 GeneticVariation BEFREE Altogether, one diffuse large B-cell lymphoma and one B-cell chronic lymphocytic leukemia (B-CLL) harbored a mutation (G12S and G12A, respectively) in the K-ras gene, and one B-CLL harbored a mutation (Q61R) in the N-ras gene. 9139869

1997

dbSNP: rs121913529
rs121913529
0.010 GeneticVariation BEFREE Altogether, one diffuse large B-cell lymphoma and one B-cell chronic lymphocytic leukemia (B-CLL) harbored a mutation (G12S and G12A, respectively) in the K-ras gene, and one B-CLL harbored a mutation (Q61R) in the N-ras gene. 9139869

1997

dbSNP: rs121913530
rs121913530
0.010 GeneticVariation BEFREE Altogether, one diffuse large B-cell lymphoma and one B-cell chronic lymphocytic leukemia (B-CLL) harbored a mutation (G12S and G12A, respectively) in the K-ras gene, and one B-CLL harbored a mutation (Q61R) in the N-ras gene. 9139869

1997

dbSNP: rs5443
rs5443
0.010 GeneticVariation BEFREE The CC genotype of the C825T polymorphism of the G protein beta3 gene (GNB3) is associated with a high relapse rate in patients with chronic lymphocytic leukaemia. 14692527

2003

dbSNP: rs1217691063
rs1217691063
0.030 GeneticVariation BEFREE Methylenetetrahydrofolate reductase (MTHFR) gene 677C>T and 1298A>C polymorphisms are associated with differential apoptosis of leukemic B cells in vitro and disease progression in chronic lymphocytic leukemia. 15385937

2004

dbSNP: rs1799945
rs1799945
0.010 GeneticVariation BEFREE With H63D, increased OR occurred in myeloproliferative disorders and adenocarcinomas of breast and prostate (2.4, 2.0, and 2.0, respectively); OR was decreased in non-Hodgkin lymphoma and B-chronic lymphocytic leukemia (0.5 and 0.4, respectively). 15018631

2004

dbSNP: rs397507444
rs397507444
0.010 GeneticVariation BEFREE While progression-free survival (PFS) was not significantly different in individuals with CLL including all stages, in patients with Binet stage A PFS was significantly longer in patients displaying the MTHFR 677CC (P=0.043) and the MTHFR 1298A/C or CC genotypes (P=0.019). 15385937

2004

dbSNP: rs758272654
rs758272654
0.020 GeneticVariation BEFREE Here, we show that the GNAS1 T393C status is a novel independent prognostic marker in patients with B-CLL. 17020971

2006

dbSNP: rs1373425060
rs1373425060
AK3
0.010 GeneticVariation BEFREE Anti-ZAP-70 moAb clone 17A/P-ZAP70 gave elevated results for all B-CLL patients as well as healthy controls. 16906577

2006

dbSNP: rs146850453
rs146850453
0.010 GeneticVariation BEFREE To explore the relationship between polymorphic variation in ARTLS1 and risk of chronic lymphocytic leukemia (CLL) we analyzed germline DNA from 413 cases and 471 healthy controls for W149X and five additional coding SNPs, S99S, P131L, L132L, C148R, and E164K. 16581122

2006

dbSNP: rs147120792
rs147120792
0.010 GeneticVariation BEFREE To explore the relationship between polymorphic variation in ARTLS1 and risk of chronic lymphocytic leukemia (CLL) we analyzed germline DNA from 413 cases and 471 healthy controls for W149X and five additional coding SNPs, S99S, P131L, L132L, C148R, and E164K. 16581122

2006

dbSNP: rs20576
rs20576
0.010 GeneticVariation BEFREE In this study we analyzed the complete coding region of TNFRSF10A and TNFRSF10B in a series of 32 MCL and 101 CLL samples and detected a single nucleotide polymorphism (SNP) in TNFRSF10A (A683C) with tumor specific allele distribution. 16217763

2006

dbSNP: rs34301344
rs34301344
0.010 GeneticVariation BEFREE To explore the relationship between polymorphic variation in ARTLS1 and risk of chronic lymphocytic leukemia (CLL) we analyzed germline DNA from 413 cases and 471 healthy controls for W149X and five additional coding SNPs, S99S, P131L, L132L, C148R, and E164K. 16581122

2006

dbSNP: rs3803185
rs3803185
0.010 GeneticVariation BEFREE To explore the relationship between polymorphic variation in ARTLS1 and risk of chronic lymphocytic leukemia (CLL) we analyzed germline DNA from 413 cases and 471 healthy controls for W149X and five additional coding SNPs, S99S, P131L, L132L, C148R, and E164K. 16581122

2006

dbSNP: rs755100942
rs755100942
0.010 GeneticVariation BEFREE To explore the relationship between polymorphic variation in ARTLS1 and risk of chronic lymphocytic leukemia (CLL) we analyzed germline DNA from 413 cases and 471 healthy controls for W149X and five additional coding SNPs, S99S, P131L, L132L, C148R, and E164K. 16581122

2006