|
rs12291063
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Binding and transactivation functions are both disrupted by substituting C for T. These findings provide a rationale for BDNF augmentation as a targeted treatment for obesity in individuals who have the rs12291063 CC genotype.
|
26526993 |
2015 |
|
rs10767664
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Cardiovascular Risk Factors and Insulin Resistance after Two Hypocaloric Diets with Different Fat Distribution in Obese Subjects: Effect of the rs10767664 Gene Variant in Brain-Derived Neurotrophic Factor.
|
29339649 |
2017 |
|
rs10767664
|
|
|
0.020 |
GeneticVariation |
BEFREE |
rs10767664 Gene Variant in Brain-Derived Neurotrophic Factor Is Associated with Diabetes Mellitus Type 2 in Caucasian Females with Obesity.
|
28595187 |
2017 |
|
rs746682028
|
|
|
0.030 |
GeneticVariation |
BEFREE |
The brain-derived neurotrophic factor (BDNF) rs6265 (G196A; Val66Met) single nucleotide polymorphism has been associated with BMI and obesity in distinct populations, both adult and pediatric, with contradictory results involving either Val or Met as the risk variant.
|
29506764 |
2017 |
|
rs746682028
|
|
|
0.030 |
GeneticVariation |
BEFREE |
BDNF196G/G genotype was more common and BDNF 196G/A polymorphism was less common among OSAS+ obesity- subjects compared to the other study groups.
|
27166632 |
2016 |
|
rs746682028
|
|
|
0.030 |
GeneticVariation |
BEFREE |
No association was found between the BDNF G196A (Val66Met) polymorphism and diabetes or obesity.
|
17151862 |
2007 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
It seems that plasma BDNF levels were associated with both ob</span>esity and BDNF V</span>al66Met SNP.
|
31004714 |
2019 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
In this cross-sectional study, the rs6265 polymorphism was not associated with a higher risk of obesity, or lower circulating levels of BDNF.
|
30418087 |
2019 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
In addition, BDNF rs6265 and MC4R rs17782313 showed gender-dependent associations with decreased risk of having low HDL-C in males and increased risk of having abdominal obesity in females, respectively.
|
31502573 |
2019 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The BDNF rs6265, in the presence of obesity, may be associated with elevated risk of anomalous metabolic, behavioural and physical traits and obesity-related co-morbidities, but it needs to be validated in a significantly larger Pakistani sample population.
|
30590963 |
2019 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
It seems that plasma BDNF levels were associated with both ob</span>esity and BDNF V</span>al66Met SNP.
|
31004714 |
2019 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The amino acid-changing exonic variant rs6265 (Val66Met polymorphism) in the brain-derived neurotrophic factor (BDNF) has been linked to obesity in several genotype-phenotype association studies.
|
28960774 |
2018 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The amino acid-changing exonic variant rs6265 (Val66Met polymorphism) in the brain-derived neurotrophic factor (BDNF) has been linked to obesity in several genotype-phenotype association studies.
|
28960774 |
2018 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The SNP rs6265 was significantly associated with adiponectin under an additive model (<i>P</i> = 0.02 and 0.024, resp.) after adjustment for age, gender, and BMI or obesity statuses.
|
28396685 |
2017 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Association Between the Brain-derived Neurotrophic Factor Val66Met Polymorphism and Overweight/Obesity in Pediatric Population.
|
29506764 |
2017 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The study suggested the significant association of delivery method, birth weight, night sleep duration, and BDNF Val66Met polymorphism, with obesity in Vietnamese primary school children.
|
28471701 |
2017 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Association Between the Brain-derived Neurotrophic Factor Val66Met Polymorphism and Overweight/Obesity in Pediatric Population.
|
29506764 |
2017 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The study suggested the significant association of delivery method, birth weight, night sleep duration, and BDNF Val66Met polymorphism, with obesity in Vietnamese primary school children.
|
28471701 |
2017 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
BDNF rs6265 polymorphism is associated with BMI categories, and the BDNF Met/Met genotype has a protective role in obesity in healthy subjects, while this effect was not present in patients with CHD.
|
27608901 |
2016 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
BDNF196G/G genotype was more common and BDNF 196G/A polymorphism was less common among OSAS+ obesity- subjects compared to the other study groups.
|
27166632 |
2016 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
BDNF196G/G genotype was more common and BDNF 196G/A polymorphism was less common among OSAS+ obesity- subjects compared to the other study groups.
|
27166632 |
2016 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The functional BDNF Val66Met polymorphism (rs6265) has been associated with CHD, obesity and BMI.
|
27608901 |
2016 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The positive association of BNDF Val66Met with high BMI values replicates previous findings in patients with SCZ and indicates the BDNF Val66Met genotype as a potential risk factor for obesity and insulin resistance measures in patients with BPD receiving antipsychotics as well.
|
25874530 |
2015 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Variants in BDNF, in particular the functional Val66Met polymorphism (rs6265), have been found to be associated with a number of psychiatric disorders, cognitive function, and obesity.
|
24708359 |
2015 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Variants in BDNF, in particular the functional Val66Met polymorphism (rs6265), have been found to be associated with a number of psychiatric disorders, cognitive function, and obesity.
|
24708359 |
2015 |