Source: BEFREE ×
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs6265
rs6265
0.100 GeneticVariation BEFREE It seems that plasma BDNF levels were associated with both ob</span>esity and BDNF V</span>al66Met SNP. 31004714

2019

dbSNP: rs6265
rs6265
0.100 GeneticVariation BEFREE In this cross-sectional study, the rs6265 polymorphism was not associated with a higher risk of obesity, or lower circulating levels of BDNF. 30418087

2019

dbSNP: rs6265
rs6265
0.100 GeneticVariation BEFREE In addition, BDNF rs6265 and MC4R rs17782313 showed gender-dependent associations with decreased risk of having low HDL-C in males and increased risk of having abdominal obesity in females, respectively. 31502573

2019

dbSNP: rs6265
rs6265
0.100 GeneticVariation BEFREE The BDNF rs6265, in the presence of obesity, may be associated with elevated risk of anomalous metabolic, behavioural and physical traits and obesity-related co-morbidities, but it needs to be validated in a significantly larger Pakistani sample population. 30590963

2019

dbSNP: rs759834365
rs759834365
0.100 GeneticVariation BEFREE It seems that plasma BDNF levels were associated with both ob</span>esity and BDNF V</span>al66Met SNP. 31004714

2019

dbSNP: rs6265
rs6265
0.100 GeneticVariation BEFREE The amino acid-changing exonic variant rs6265 (Val66Met polymorphism) in the brain-derived neurotrophic factor (BDNF) has been linked to obesity in several genotype-phenotype association studies. 28960774

2018

dbSNP: rs759834365
rs759834365
0.100 GeneticVariation BEFREE The amino acid-changing exonic variant rs6265 (Val66Met polymorphism) in the brain-derived neurotrophic factor (BDNF) has been linked to obesity in several genotype-phenotype association studies. 28960774

2018

dbSNP: rs6265
rs6265
0.100 GeneticVariation BEFREE The SNP rs6265 was significantly associated with adiponectin under an additive model (<i>P</i> = 0.02 and 0.024, resp.) after adjustment for age, gender, and BMI or obesity statuses. 28396685

2017

dbSNP: rs6265
rs6265
0.100 GeneticVariation BEFREE Association Between the Brain-derived Neurotrophic Factor Val66Met Polymorphism and Overweight/Obesity in Pediatric Population. 29506764

2017

dbSNP: rs6265
rs6265
0.100 GeneticVariation BEFREE The study suggested the significant association of delivery method, birth weight, night sleep duration, and BDNF Val66Met polymorphism, with obesity in Vietnamese primary school children. 28471701

2017

dbSNP: rs759834365
rs759834365
0.100 GeneticVariation BEFREE Association Between the Brain-derived Neurotrophic Factor Val66Met Polymorphism and Overweight/Obesity in Pediatric Population. 29506764

2017

dbSNP: rs759834365
rs759834365
0.100 GeneticVariation BEFREE The study suggested the significant association of delivery method, birth weight, night sleep duration, and BDNF Val66Met polymorphism, with obesity in Vietnamese primary school children. 28471701

2017

dbSNP: rs6265
rs6265
0.100 GeneticVariation BEFREE BDNF rs6265 polymorphism is associated with BMI categories, and the BDNF Met/Met genotype has a protective role in obesity in healthy subjects, while this effect was not present in patients with CHD. 27608901

2016

dbSNP: rs6265
rs6265
0.100 GeneticVariation BEFREE BDNF196G/G genotype was more common and BDNF 196G/A polymorphism was less common among OSAS+ obesity- subjects compared to the other study groups. 27166632

2016

dbSNP: rs759834365
rs759834365
0.100 GeneticVariation BEFREE BDNF196G/G genotype was more common and BDNF 196G/A polymorphism was less common among OSAS+ obesity- subjects compared to the other study groups. 27166632

2016

dbSNP: rs759834365
rs759834365
0.100 GeneticVariation BEFREE The functional BDNF Val66Met polymorphism (rs6265) has been associated with CHD, obesity and BMI. 27608901

2016

dbSNP: rs6265
rs6265
0.100 GeneticVariation BEFREE The positive association of BNDF Val66Met with high BMI values replicates previous findings in patients with SCZ and indicates the BDNF Val66Met genotype as a potential risk factor for obesity and insulin resistance measures in patients with BPD receiving antipsychotics as well. 25874530

2015

dbSNP: rs6265
rs6265
0.100 GeneticVariation BEFREE Variants in BDNF, in particular the functional Val66Met polymorphism (rs6265), have been found to be associated with a number of psychiatric disorders, cognitive function, and obesity. 24708359

2015

dbSNP: rs759834365
rs759834365
0.100 GeneticVariation BEFREE Variants in BDNF, in particular the functional Val66Met polymorphism (rs6265), have been found to be associated with a number of psychiatric disorders, cognitive function, and obesity. 24708359

2015

dbSNP: rs759834365
rs759834365
0.100 GeneticVariation BEFREE The positive association of BNDF Val66Met with high BMI values replicates previous findings in patients with SCZ and indicates the BDNF Val66Met genotype as a potential risk factor for obesity and insulin resistance measures in patients with BPD receiving antipsychotics as well. 25874530

2015

dbSNP: rs6265
rs6265
0.100 GeneticVariation BEFREE Our aim is to elucidate whether the interaction between the Brain Derived Neurotrophic Factor val66met polymorphism and obesity status influences executive performance and frontal-subcortical brain structure. 24619555

2014

dbSNP: rs759834365
rs759834365
0.100 GeneticVariation BEFREE Our aim is to elucidate whether the interaction between the Brain Derived Neurotrophic Factor val66met polymorphism and obesity status influences executive performance and frontal-subcortical brain structure. 24619555

2014

dbSNP: rs6265
rs6265
0.100 GeneticVariation BEFREE In a partial replication of prior research, the obesity risk (G) allele at BDNF rs6265 was associated with greater weight regain across treatment arms (0.773 kg per risk allele), although results were of borderline statistical significance (P=0.051). 23628854

2013

dbSNP: rs6265
rs6265
0.100 GeneticVariation BEFREE Our study replicates the statistically significant association of four SNPs (FTO rs9939609, MC4R rs17782313, GNPDA2 rs10938397, BDNF rs6265) with risk of central obesity in the Chinese children. 23424664

2013

dbSNP: rs6265
rs6265
0.100 GeneticVariation BEFREE A common polymorphism of the BDNF genotype (Val66Met) has been associated with various forms of eating disorders, alterations in body mass index (BMI) values and obesity in adult populations. 21851847

2012