|
rs2285450
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Two synonymous NPHS1 polymorphisms, rs2285450 (c.294C>T) and rs437168 (c.2289C>T) segregated with renal failure in this family.
|
26147534 |
2015 |
|
rs28933979
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Renal manifestations of ATTR V30M, like other amyloidoses, are different levels of proteinuria and renal insufficiency.
|
12832749 |
2003 |
|
rs3024912
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In addition, the individuals with the GG genotype at rs3024912 SNP may have a higher risk in kidney failure of MGN patients (adjusted odds ratio [OR]=3.255; 95% confidence interval [CI]=1.155-9.176, p=0.026).
|
21740896 |
2011 |
|
rs367825197
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In the present study, we report the identification of a heterozygous nonsense <i>PODXL</i> mutation (c.C976T; p. Arg326X) in a Chinese pedigree featured by proteinuria and renal insufficiency with AD inheritance by whole exome sequencing (WES).
|
30523047 |
2019 |
|
rs3752462
|
|
|
0.010 |
GeneticVariation |
BEFREE |
MYH9 SNPs rs4821480, rs2032487, rs4281481 and rs3752462 are associated with T2DM-ESRD susceptibility in European Americans.
|
21968013 |
2012 |
|
rs3759126
|
|
|
0.010 |
GeneticVariation |
BEFREE |
No correlation was found to exist between the AQP-2 gene polymorphism (rs3759126) and serum electrolyte levels in pre-ESRD patients (p = 0.38 for serum sodium level and p = 0.44 for serum potassium level).
|
17763164 |
2007 |
|
rs4281481
|
|
|
0.010 |
GeneticVariation |
BEFREE |
MYH9 SNPs rs4821480, rs2032487, rs4281481 and rs3752462 are associated with T2DM-ESRD susceptibility in European Americans.
|
21968013 |
2012 |
|
rs4362
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Influence of angiotensin converting enzyme (<i>ACE</i>) gene rs4362 polymorphism on the progression of kidney failure in patients with autosomal dominant polycystic kidney disease (ADPKD).
|
27748299 |
2016 |
|
rs437168
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Two synonymous NPHS1 polymorphisms, rs2285450 (c.294C>T) and rs437168 (c.2289C>T) segregated with renal failure in this family.
|
26147534 |
2015 |
|
rs437168
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Two synonymous NPHS1 polymorphisms, rs2285450 (c.294C>T) and rs437168 (c.2289C>T) segregated with renal failure in this family.
|
26147534 |
2015 |
|
rs4821480
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Contrasting the 751 T2DM-ESRD cases with 227 T2DM non-nephropathy controls revealed that E1 haplotype SNPs rs4821480, rs2032487 and rs4821481 were associated with kidney failure (OR 1.38-1.40 recessive, all P < 0.048).
|
19567477 |
2009 |
|
rs4821481
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Contrasting the 751 T2DM-ESRD cases with 227 T2DM non-nephropathy controls revealed that E1 haplotype SNPs rs4821480, rs2032487 and rs4821481 were associated with kidney failure (OR 1.38-1.40 recessive, all P < 0.048).
|
19567477 |
2009 |
|
rs4961
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A single-nucleotide polymorphism (Gly460Trp) within the alpha-adducin gene (ADD1) may influence several renal phenotypes, including salt sensitivity, susceptibility to renal failure, the renal haemodynamics and confer a worse cardiovascular risks profile.
|
16612256 |
2006 |
|
rs538166970
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In contrast, another mutant, R1180P, was compatible with life after transient neonatal renal insufficiency.
|
24163131 |
2014 |
|
rs61747728
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Evidence that NPHS2-R229Q predisposes to proteinuria and renal failure in familial hematuria.
|
22228437 |
2012 |
|
rs662
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The paraoxonase (PON1) polymorphisms, Leu55Met and Gln192Arg, modulate intima-medial artery thickening, prognosis of cardiovascular stroke, and renal failure in other diseases.
|
20639675 |
2010 |
|
rs699
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We studied retrospectively the role of angiotensinogen (AGT) M235T, angiotensin converting enzyme (ACE) insertion/deletion (I/D), angiotensin II type 1 receptor (AT1R) A1166C, aldosterone syntase (CYP11B2) -344C/T and intron 2 W/C polymorphisms in conjunction with clinical and biochemical covariables on the rate of progression of renal insufficiency in a group of patients with ESRD of various etiologies.
|
12832734 |
2003 |
|
rs734553
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The strongest genetic marker of uric acid levels, the rs734553 SNP in the GLUT9 urate transporter gene, predicts progression to kidney failure in CKD patients and associates with systolic BP and carotid intima media thickness in family-based studies.
|
26607700 |
2015 |
|
rs754919065
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Here, we describe a family where six members had a novel TRPC6 p.R68W (c.202C>T) mutation, two of whom had renal failure from FSGS, and one had proteinuria.
|
26147534 |
2015 |
|
rs7582694
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In the case-only meta-analysis of the two cohorts, the STAT4 SNP rs7582694 was associated with severe renal insufficiency with p = 1.6 × 10(-3) and OR 2.22.
|
24386384 |
2013 |
|
rs760336723
|
|
|
0.010 |
GeneticVariation |
BEFREE |
However, the data do suggest that Wt1 R394W-induced glomerulosclerosis may be independent of downregulation of the genes for NPHS1, NPHS2, CD2AP, and podocalyxin and may involve other genes yet to be implicated in renal failure.
|
15509792 |
2004 |
|
rs867394500
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We studied retrospectively the role of angiotensinogen (AGT) M235T, angiotensin converting enzyme (ACE) insertion/deletion (I/D), angiotensin II type 1 receptor (AT1R) A1166C, aldosterone syntase (CYP11B2) -344C/T and intron 2 W/C polymorphisms in conjunction with clinical and biochemical covariables on the rate of progression of renal insufficiency in a group of patients with ESRD of various etiologies.
|
12832734 |
2003 |