|
rs1042579
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The <i>TM</i> C1418T (rs1042579) polymorphism is associated with a high risk of cardiac-cerebral vascular diseases.
|
30008974 |
2018 |
|
rs1967309
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A nested case-control study examining the rs1967309 SNP in 1427 cases and 1532 matched controls selected from the 12 092-patient Assessment of Clinical Effects of Cholesteryl Ester Transfer Protein Inhibition with Evacetrapib in Patients at a High Risk for Vascular Outcomes (ACCELERATE) trial, a randomized, double-blind, placebo-controlled phase 3 trial conducted in patients with high-risk vascular disease randomized from October 2012 through December 2013.
|
29525816 |
2018 |
|
rs759985000
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The manganese-dependent superoxide dismutase (MnSOD) Ala16Val single nucleotide polymorphism (SNP) has shown to be associated to risk factors of vascular diseases.
|
30150066 |
2018 |
|
rs763000109
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The manganese-dependent superoxide dismutase (MnSOD) Ala16Val single nucleotide polymorphism (SNP) has shown to be associated to risk factors of vascular diseases.
|
30150066 |
2018 |
|
rs4880
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The ALA16VAL-MnSOD gene single nucleotide polymorphism (SNP) has shown to modulate risk factors of several metabolic and vascular diseases, such as blood glucose (GLU) and lipid levels.
|
28552711 |
2017 |
|
rs9939609
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To investigate whether the FTO rs9939609 single nucleotide polymorphism (SNP), which is a risk factor for obesity and vascular diseases, is also associated with pregnancy complications including pre-eclampsia, gestational hypertension, small for gestational age pregnancy (SGA), and spontaneous preterm birth (sPTB).
|
27768255 |
2016 |
|
rs387906853
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A previously described missense mutation, p.E239K, in the SMAD3 gene was identified in a 60-year-old man who presented with diffuse vasculopathy.
|
25555948 |
2015 |
|
rs764821003
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A previously described missense mutation, p.E239K, in the SMAD3 gene was identified in a 60-year-old man who presented with diffuse vasculopathy.
|
25555948 |
2015 |
|
rs1122608
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Single-nucleotide polymorphisms associated with plasma LDL-c and vascular risk in the general population (rs11206510 (PCSK9), rs1122608 (LDLR), rs579459 (ABO) and rs599839 (SORT1)) were genotyped in a prospective cohort study of 5482 patients with vascular disease.
|
24251769 |
2014 |
|
rs267606743
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Interestingly, the COL4A1 p.Gly510Arg mutation has been previously identified in a family with HANAC (Hereditary Angiopathy with Nephropathy, Aneurysm and Cramps), a multisystemic disease featuring retinal arteriolar tortuosity.
|
25228067 |
2014 |
|
rs579459
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Single-nucleotide polymorphisms associated with plasma LDL-c and vascular risk in the general population (rs11206510 (PCSK9), rs1122608 (LDLR), rs579459 (ABO) and rs599839 (SORT1)) were genotyped in a prospective cohort study of 5482 patients with vascular disease.
|
24251769 |
2014 |
|
rs599839
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Single-nucleotide polymorphisms associated with plasma LDL-c and vascular risk in the general population (rs11206510 (PCSK9), rs1122608 (LDLR), rs579459 (ABO) and rs599839 (SORT1)) were genotyped in a prospective cohort study of 5482 patients with vascular disease.
|
24251769 |
2014 |
|
rs121918095
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We genotyped for 2 stabilizing genetic variants in the transthyretin gene (TTR), R104H and T119M, and determined the association of genotypes with plasma levels of transthyretin, measures of thyroid function, risk of vascular disease, and life expectancy.
|
23580146 |
2013 |
|
rs28933981
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We genotyped for 2 stabilizing genetic variants in the transthyretin gene (TTR), R104H and T119M, and determined the association of genotypes with plasma levels of transthyretin, measures of thyroid function, risk of vascular disease, and life expectancy.
|
23580146 |
2013 |
|
rs4977574
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The lead SNP at the 9p21 locus (rs4977574) was associated with all four vascular diseases (P < 4 × 10(-3)), illustrating the functional pleiotropy of this locus.
|
23828831 |
2013 |
|
rs1333049
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Altogether, our data indicate for the first time that the C allele of rs1333049 in the vascular disease susceptibility locus is associated with VaD and LOAD, independent of traditional risk factors and the APOE ε4 genotype.
|
19664850 |
2011 |
|
rs14259
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We then screened 200 T2D siblings/families for PSMD9 +nt460A/G, +nt437C/T and exon E197G A/G single nucleotide polymorphisms (SNPs) and performed a non-parametric linkage study to test for linkage for coronary artery disease, stroke/TIA, macro-vasculopathy and macrovascular pathology of T2D.
|
21496327 |
2011 |
|
rs72653706
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Heterozygosity for R1141X in ABCC6 and risk of ischemic vascular disease.
|
21831958 |
2011 |
|
rs765798193
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We then screened 200 T2D siblings/families for PSMD9 +nt460A/G, +nt437C/T and exon E197G A/G single nucleotide polymorphisms (SNPs) and performed a non-parametric linkage study to test for linkage for coronary artery disease, stroke/TIA, macro-vasculopathy and macrovascular pathology of T2D.
|
21496327 |
2011 |
|
rs2144151
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The multipoint linkage peak was located at marker rs2144151 in the ANGPT4 gene, which is a strong candidate gene for vascular disease because of its involvement in angiogenesis.
|
20596041 |
2010 |
|
rs1801394
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In this study, we determined total plasma homocysteine levels and MTRR A66G polymorphism in 114 patients with vascular disease: 58 patients with deep-vein thrombosis, 56 patients with arterial thrombosis, and 95 healthy subjects from the Sicilian population.
|
19348062 |
2009 |
|
rs313158
|
|
|
0.010 |
GeneticVariation |
BEFREE |
From a group of DNA samples collected at baseline in a prospective cohort of 14 916 initially healthy American men, we assessed 16 TRPM7 tag-single-nucleotide polymorphisms (SNPs) (dbSNP: rs11854949, rs4775899, rs11635825, rs12905120, rs16973487, rs7173321, rs7163283, rs17520378, rs17520350, rs4775892, rs7174839, rs17645523, rs3109894, rs616256, rs11070795, and rs313158) from 245 white men who subsequently had an incident ischemic stroke and from 245 age- and smoking habit-matched white men who remained free of reported vascular disease during follow-up (controls).
|
19644062 |
2009 |
|
rs505151
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Moreover, 6.0% were carriers of the G allele at E670G with no significant relationships with baseline LDL C, response to pravastatin, or vascular disease risk being observed.
|
18262190 |
2008 |
|
rs6809699
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Using DNA samples collected at baseline in a prospective cohort of 14,916 initially healthy American men, we examined the possible association of P2RY12 genetic variants, in particular a haplotype H2 (constituted by dbSNP rs10935838, rs2046934, rs5853517, and rs6809699) amongst 708 white males who subsequently developed a thromboembolic event (incident myocardial infarction (MI), ischemic stroke, or deep venous thromboembolism/pulmonary embolism (DVT/PE)) and amongst an equal number of age- and smoking-matched white males who remained free of reported vascular disease during follow-up (controls).
|
17707382 |
2008 |
|
rs1061170
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We, therefore, evaluated the CFH genetic variant Y402H amongst 685 Caucasian individuals who subsequently developed arterial or venous thrombotic event (incident myocardial infarction (MI), ischaemic stroke, or venous thromboembolism) and amongst 685 age- and smoking-matched Caucasian individuals who remained free of reported vascular disease during follow-up (controls) within the Physicians' Health Study cohort.
|
16229850 |
2006 |