Gene: TP53 ×
Source: CLINVAR ×
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs730882029
rs730882029
TP53
A 0.700 CausalMutation CLINVAR Detection of high frequency of mutations in a breast and/or ovarian cancer cohort: implications of embracing a multi-gene panel in molecular diagnosis in India. 26911350

2016
dbSNP: rs730882029
rs730882029
TP53
A 0.700 CausalMutation CLINVAR Complex analysis of the p53 tumor suppressor in lung carcinoma. 26718964

2016
dbSNP: rs760043106
rs760043106
TP53
G 0.700 CausalMutation CLINVAR Targeted massively parallel sequencing of a panel of putative breast cancer susceptibility genes in a large cohort of multiple-case breast and ovarian cancer families. 26534844

2016
dbSNP: rs786201057
rs786201057
TP53
A 0.700 GeneticVariation CLINVAR Improving performance of multigene panels for genomic analysis of cancer predisposition. 26845104

2016
dbSNP: rs866380588
rs866380588
TP53
A 0.700 CausalMutation CLINVAR Morphologic correlates of molecular alterations in extrauterine Müllerian carcinomas. 27150160

2016
dbSNP: rs866380588
rs866380588
TP53
A 0.700 CausalMutation CLINVAR TP53 mutations in older adults with acute myeloid leukemia. 26781615

2016
dbSNP: rs868137297
rs868137297
TP53
T 0.700 GeneticVariation CLINVAR Biochemical and imaging surveillance in germline TP53 mutation carriers with Li-Fraumeni syndrome: 11 year follow-up of a prospective observational study. 27501770

2016
dbSNP: rs1057519989
rs1057519989
TP53
T 0.700 CausalMutation CLINVAR Germline TP53 mutational spectrum in French Canadians with breast cancer. 25925845

2015
dbSNP: rs1064795203
rs1064795203
TP53
C 0.700 GeneticVariation CLINVAR Detection of novel germline mutations for breast cancer in non-BRCA1/2 families. 26094658

2015
dbSNP: rs112431538
rs112431538
TP53
T 0.700 CausalMutation CLINVAR Prevalence and functional consequence of TP53 mutations in pediatric adrenocortical carcinoma: a children's oncology group study. 25584008

2015
dbSNP: rs121912655
rs121912655
TP53
T 0.700 CausalMutation CLINVAR Germline TP53 variants and susceptibility to osteosarcoma. 25896519

2015
dbSNP: rs121912667
rs121912667
TP53
A 0.700 CausalMutation CLINVAR Prevalence and functional consequence of TP53 mutations in pediatric adrenocortical carcinoma: a children's oncology group study. 25584008

2015
dbSNP: rs1555525367
rs1555525367
TP53
T 0.700 GeneticVariation CLINVAR Revisiting Li-Fraumeni Syndrome From TP53 Mutation Carriers. 26014290

2015
dbSNP: rs1555526750
rs1555526750
TP53
A 0.700 CausalMutation CLINVAR Prevalence and functional consequence of TP53 mutations in pediatric adrenocortical carcinoma: a children's oncology group study. 25584008

2015
dbSNP: rs1567553501
rs1567553501
TP53
AA 0.700 CausalMutation CLINVAR Prevalence and functional consequence of TP53 mutations in pediatric adrenocortical carcinoma: a children's oncology group study. 25584008

2015
dbSNP: rs55863639
rs55863639
TP53
T 0.700 CausalMutation CLINVAR DNA methylation patterns of candidate genes regulated by thymine DNA glycosylase in patients with TP53 germline mutations. 25945745

2015
dbSNP: rs55863639
rs55863639
TP53
T 0.700 CausalMutation CLINVAR Prevalence and functional consequence of TP53 mutations in pediatric adrenocortical carcinoma: a children's oncology group study. 25584008

2015
dbSNP: rs587781525
rs587781525
TP53
C 0.700 CausalMutation CLINVAR Germline TP53 mutations is common in patients with two early-onset primary malignancies. 25293557

2015
dbSNP: rs587781525
rs587781525
TP53
A 0.700 CausalMutation CLINVAR Germline TP53 mutations is common in patients with two early-onset primary malignancies. 25293557

2015
dbSNP: rs587781664
rs587781664
TP53
C 0.700 CausalMutation CLINVAR Regulation of the p53 response and its relationship to cancer. 26205489

2015
dbSNP: rs730882029
rs730882029
TP53
A 0.700 CausalMutation CLINVAR TP53 Mutational Status and Prediction of Benefit from Adjuvant 5-Fluorouracil in Stage III Colon Cancer Patients. 26425688

2015
dbSNP: rs755394212
rs755394212
TP53
A 0.700 GeneticVariation CLINVAR The p53 C terminus controls site-specific DNA binding and promotes structural changes within the central DNA binding domain. 25794615

2015
dbSNP: rs755394212
rs755394212
TP53
A 0.700 GeneticVariation CLINVAR Regulation of the p53 response and its relationship to cancer. 26205489

2015
dbSNP: rs786201057
rs786201057
TP53
A 0.700 GeneticVariation CLINVAR Prevalence of mutations in a panel of breast cancer susceptibility genes in BRCA1/2-negative patients with early-onset breast cancer. 25503501

2015
dbSNP: rs786201057
rs786201057
TP53
A 0.700 GeneticVariation CLINVAR Revisiting Li-Fraumeni Syndrome From TP53 Mutation Carriers. 26014290

2015