|
rs7481311
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Haplotype analysis shown that haplotype "GCC" in the block (rs988712, rs7481311, and rs11030064) increased LDH risk (OR = 1.49, 95% CI = 1.06-2.10, p = 0.022) at age ≤50 years.
|
30143695 |
2018 |
|
rs79845319
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The SNP rs17576 was found to be significantly associated with susceptibility to LDH (OR = 0.77, p = 0.0002), which was also confirmed by haplotype-based analyses (rs79845319-rs17576-rs45437897, global p < 0.001).
|
30289281 |
2018 |
|
rs886205
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Additionally, the haplotype "GGCTCACG" constructed by rs886205, rs2238152, rs4648328, rs441, rs4646778, rs671, rs11066028, and rs7296651 was associated with increased risk of LDH (OR = 1.45; 95% CI = 1.11-1.90; P = 0.0071).
|
30166580 |
2018 |
|
rs143383
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The aim of the present study is to assess whether the single nucleotide polymorphism in the GDF5 (+104T/C; rs143383) is associated with the symptomatic lumbar disc herniation in the Chinese Han population and the identification of the mechanisms of its action.
|
24105021 |
2014 |
|
rs2615977
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This corresponded with observations in LDH but the SNP was not associated with OA.We did not observe AEI at rs2615977.
|
23497244 |
2013 |
|
rs1799971
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Pain intensity the first year after lumbar disc herniation is associated with the A118G polymorphism in the opioid receptor mu 1 gene: evidence of a sex and genotype interaction.
|
22815498 |
2012 |
|
rs4680
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We conclude that the functional COMT Val158Met SNP contributes to long lasting low back pain, sciatica and disability after lumbar disc herniation.
|
22337560 |
2012 |
|
rs1400328611
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The eNOS (-786 T/C) and iNOS (22 G/A) SNPs were more frequent among the control subjects, suggesting their possible protective role against LDH.
|
21837414 |
2011 |
|
rs375081888
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The eNOS (-786 T/C) and iNOS (22 G/A) SNPs were more frequent among the control subjects, suggesting their possible protective role against LDH.
|
21837414 |
2011 |
|
rs762704392
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The eNOS (-786 T/C) and iNOS (22 G/A) SNPs were more frequent among the control subjects, suggesting their possible protective role against LDH.
|
21837414 |
2011 |
|
rs9406328
|
|
|
0.010 |
GeneticVariation |
BEFREE |
An intronic SNP in THBS2 (IVS10-8C --> T; rs9406328) showed significant association (p = 0.0000028) with LDH in two independent Japanese populations.
|
18455130 |
2008 |