|
rs11571297
|
|
G |
0.700 |
GeneticVariation |
GWASCAT |
Seven newly identified loci for autoimmune thyroid disease.
|
22922229 |
2012 |
|
rs12507813
|
|
G |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide association analysis suggests novel loci underlying thyroid antibodies in Hashimoto's thyroiditis.
|
30926877 |
2019 |
|
rs12551356
|
|
G |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide association analysis suggests novel loci underlying thyroid antibodies in Hashimoto's thyroiditis.
|
30926877 |
2019 |
|
rs4409785
|
|
C |
0.700 |
GeneticVariation |
GWASCAT |
Seven newly identified loci for autoimmune thyroid disease.
|
22922229 |
2012 |
|
rs57348955
|
|
G |
0.700 |
GeneticVariation |
GWASCAT |
Seven newly identified loci for autoimmune thyroid disease.
|
22922229 |
2012 |
|
rs6972286
|
|
A |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide association analysis suggests novel loci underlying thyroid antibodies in Hashimoto's thyroiditis.
|
30926877 |
2019 |
|
rs977706
|
|
A |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide association analysis suggests novel loci underlying thyroid antibodies in Hashimoto's thyroiditis.
|
30926877 |
2019 |
|
rs12944194
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We identified three variants suggestively associated with HT: rs12944194 located 206 kb from SDK2 (P = 1.8 × 10<sup>-6</sup>), rs75201096 inside GNA14 (P = 2.41 × 10<sup>-5</sup>) and rs791903 inside IP6K3 (P = 3.16 × 10<sup>-5</sup>).
|
30284222 |
2019 |
|
rs17445836
|
|
|
0.010 |
GeneticVariation |
BEFREE |
rs17445836 of IRF8 is a possible genetic variant associated with the development of HT. rs17445836 was associated with the production of thyroid antibody, and the GG genotype of rs17445836 was associated with a higher AmiA titre than the GA genotype.
|
25989711 |
2015 |
|
rs2736340
|
|
|
0.010 |
GeneticVariation |
BEFREE |
At the same time, lower frequencies of the C allele of rs2736340 of BLK in GD (P = 0.025, OR = 0.76, 95% CI = 0.60-0.97) and HT (P = 0.003, OR = 0.53, 95% CI = 0.35-0.81) than the controls were also observed.
|
30589937 |
2019 |
|
rs6887695
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In Australian men (but not women), rs6887695 genotype differed between Hashimoto's disease and Graves' disease, with a minor allele frequency (MAF) of 14% and 41%, respectively (P=0·034).
|
21198744 |
2011 |
|
rs7178239
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The allele C and genotype CC in rs7178239 of SELENOS showed different trend in GD and HT patients when compared with the control.
|
28499373 |
2017 |
|
rs8099917
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Using the polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) method, single-nucleotide polymorphisms (SNPs) of IL28B rs8099917 (IL28 G/T) and IL29 rs30461 (IL29 T/C) were studied in 99 patients with HT and 100 healthy controls.
|
27617784 |
2016 |
|
rs917997
|
|
|
0.010 |
GeneticVariation |
BEFREE |
And in another SNP rs917997, AA+AG genotype presented an increased frequency in HT subjects compared with controls (P = 0.046, OR = 1.53).
|
26566691 |
2016 |
|
rs2234767
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Association of the blood serum cytokines' rate and lymphocytes' apoptosis with polymorphic variants of the BCL-2 (rs17759659), CTLA-4 (rs231775) and APO-1÷FAS (rs2234767) genes in patients with nodular goiters in autoimmune thyroiditis and thyroid adenoma.
|
29250672 |
2017 |
|
rs2292779
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We genotyped AGO1 rs636832A/G, AGO2 rs7005286C/T, AGO2 rs11166985A/G and AGO2 rs2292779C/G polymorphisms in 184 Graves' disease (GD) patients, 195 Hashimoto's disease (HD) patients and 122 healthy volunteers using the polymerase chain reaction-restriction fragment length polymorphism method.
|
29256262 |
2018 |
|
rs121434257
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The G228W closely cosegregated with hypothyroid autoimmune thyroiditis in our family, whereas a low penetrance of the full autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy phenotype was observed.
|
11600535 |
2001 |
|
rs6479778
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Fine mapping of the AITD locus, 10q, showed replicated association of the AITD phenotype (both GD and HT) with SNP rs6479778.
|
23118423 |
2013 |
|
rs10774625
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Three genetic variants showed nominal association with HT; rs10774625 in ATXN2 gene (p = 0.0149, OR = 0.73, CI = 0.56-0.94), rs7171171 near RASGRP1 gene (p = 0.0356, OR = 1.4, CI = 1.02-1.92) and rs11675434 in TPO gene (p = 0.041, OR = 1.31, CI = 1.01-1.69).
|
27268232 |
2016 |
|
rs72928038
|
|
A |
0.700 |
GeneticVariation |
GWASCAT |
Seven newly identified loci for autoimmune thyroid disease.
|
22922229 |
2012 |
|
rs3733197
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Also SNP rs3733197 A allele showed a significant association in HT patients when compared with controls (P=0.031, OR=0.73 and 95% CI=0.55-0.97).
|
24127308 |
2013 |
|
rs17759659
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Association of the blood serum cytokines' rate and lymphocytes' apoptosis with polymorphic variants of the BCL-2 (rs17759659), CTLA-4 (rs231775) and APO-1÷FAS (rs2234767) genes in patients with nodular goiters in autoimmune thyroiditis and thyroid adenoma.
|
29250672 |
2017 |
|
rs13277113
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our results showed reduced percentages of the G allele of rs13277113 of BLK in GD (P = 0.037, odds ratio [OR] = 0.78, 95% confidence interval [CI] = 0.62-0.99) and HT (P = 0.002, OR = 0.54, 95% CI = 0.36-0.81), compared to the controls.
|
30589937 |
2019 |
|
rs113488022
|
|
|
0.100 |
GeneticVariation |
BEFREE |
BRAF(V600E) mutation is associated with a more advanced PTC at diagnosis; however, its role in the clinicopathological characteristics of PTC with concurrent HT is unknown.
|
23469895 |
2013 |
|
rs113488022
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Association between BRAF V600E Mutation and Ultrasound Features in Papillary Thyroid Carcinoma Patients with and without Hashimoto's Thyroiditis.
|
28687736 |
2017 |