|
rs191257018
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A novel amino acid change, F340S, was found in a patient with sporadic colon and breast cancer and leukemia but was not detected in 246 chromosomes from healthy anonymous blood donors.
|
10699937 |
2000 |
|
rs61753793
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A novel amino acid change, F340S, was found in a patient with sporadic colon and breast cancer and leukemia but was not detected in 246 chromosomes from healthy anonymous blood donors.
|
10699937 |
2000 |
|
rs1695
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Association between survival after treatment for breast cancer and glutathione S-transferase P1 Ile105Val polymorphism.
|
11059750 |
2000 |
|
rs144848
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Here we show that a common human polymorphism (N372H) in exon 10 of BRCA2 confers an increased risk of breast cancer: the HH homozygotes have a 1.31-fold (95% CI, 1.07-1.61) greater risk than the NN group.
|
11062481 |
2000 |
|
rs4680
|
|
|
0.100 |
GeneticVariation |
BEFREE |
A valine-108-methionine polymorphism in exon 4 of the catechol-O-methyltransferase (COMT) gene causes a 3- to 4-fold reduction in enzyme activity and has been associated with an increased risk of breast cancer.
|
11142424 |
2000 |
|
rs80358547
|
|
|
0.010 |
GeneticVariation |
BEFREE |
RNA analysis from a breast cancer patient with BRCA2 IVS7 + 2T --> G showed that the productive message was produced from only one chromosome.
|
11185744 |
2000 |
|
rs1799782
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We examined the association of polymorphisms in XRCC1 (codon 194 Arg-->Trp and codon 399 Arg-->Gln) and breast cancer in the Carolina Breast Cancer Study, a population-based case-control study in North Carolina.
|
11303590 |
2001 |
|
rs25487
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We examined the association of polymorphisms in XRCC1 (codon 194 Arg-->Trp and codon 399 Arg-->Gln) and breast cancer in the Carolina Breast Cancer Study, a population-based case-control study in North Carolina.
|
11303590 |
2001 |
|
rs4680
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Relationship between the Val158Met polymorphism of catechol O-methyl transferase and breast cancer.
|
11434504 |
2001 |
|
rs4680
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Several studies have indicated that the val108met COMT polymorphism, which results in a 3-4-fold decrease in activity, is associated with increased breast cancer risk.
|
11577006 |
2001 |
|
rs1048943
|
|
|
0.080 |
GeneticVariation |
BEFREE |
The genotype distribution of Ile462Val in controls was also close to that expected under HWE with no significant differences between breast cancer cases and the controls (P = 0.44).
|
11698341 |
2001 |
|
rs1799814
|
|
|
0.030 |
GeneticVariation |
BEFREE |
We have carried out a population based case-control study of the Thr461Asn and Ile462Val polymorphisms in CYP1A1 to clarify their importance in determining breast cancer susceptibility.
|
11698341 |
2001 |
|
rs4680
|
|
|
0.100 |
GeneticVariation |
BEFREE |
To date, three studies in Caucasians and one study in Chinese have been conducted to determine the association with breast cancer risk of a functional polymorphism (G-to-A, Val158Met) of this enzyme, but the results were inconsistent.
|
11706521 |
2001 |
|
rs1136201
|
|
|
0.100 |
GeneticVariation |
BEFREE |
In this analysis, we measured the association between the Ile(655)Val variant and postmenopausal breast cancer among women participating in the Hawaii and Los Angeles Multiethnic Cohort.
|
11731415 |
2001 |
|
rs28904921
|
|
|
0.080 |
GeneticVariation |
BEFREE |
Nevertheless, two recurrent ATM mutations, T7271G and IVS10-6T-->G, reportedly increase the risk of breast cancer.
|
11830610 |
2002 |
|
rs1799950
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Q356R and S1512I are BRCA1 variants that may be associated with breast cancer in a Cypriot family.
|
11836613 |
2002 |
|
rs80357796
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Q356R and S1512I are BRCA1 variants that may be associated with breast cancer in a Cypriot family.
|
11836613 |
2002 |
|
rs1800744
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Q356R and S1512I are BRCA1 variants that may be associated with breast cancer in a Cypriot family.
|
11836613 |
2002 |
|
rs1136201
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Recent studies indicated an association between the Ile to Val polymorphism at codon 655 of HER-2 and susceptibility to breast cancer.
|
11857355 |
2002 |
|
rs1136201
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We have also evaluated a Val(655)Ile single nucleotide polymorphism, which is associated with an increased risk of breast cancer, in a subset of the colorectal cancer patients and in healthy control subjects.
|
11870539 |
2002 |
|
rs2236722
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Aromatase and breast cancer: W39R, an inactive protein.
|
11916629 |
2002 |
|
rs144848
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The BRCA2 N372H polymorphism appears to be associated with a modest recessively inherited risk of breast cancer in Australian women.
|
11927503 |
2002 |
|
rs1042838
|
|
|
0.060 |
GeneticVariation |
BEFREE |
The progesterone receptor exon 4 Val660Leu G/T polymorphism and risk of breast cancer in Australian women.
|
12010857 |
2002 |
|
rs1056836
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We sought to determine whether two common functional polymorphisms in Cytochrome P450 1B1, V432L (m1), and A453S (m2) are related to breast cancer risk.
|
12010864 |
2002 |
|
rs3218536
|
|
|
0.090 |
GeneticVariation |
BEFREE |
Carriage of the rare allele of XRCC2 R1</span>88H was associated with breast cancer overall [odds ratio 1.3; 95% confidence interval (CI)=(1.0, 1.8)] and when younger-onset cases with a positive family history were compared with older controls with no family history [odds ratio 1.9; 95% CI=(1.0, 3.8)].
|
12023985 |
2002 |