|
rs746481984
|
|
G |
0.720 |
CausalMutation |
CLINVAR |
|
|
|
|
rs112445441
|
|
|
0.700 |
GeneticVariation |
UNIPROT |
|
|
|
|
rs1203145163
|
|
|
0.700 |
GeneticVariation |
UNIPROT |
|
|
|
|
rs1400295986
|
|
|
0.700 |
GeneticVariation |
UNIPROT |
|
|
|
|
rs1555515731
|
|
G |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
|
rs180177133
|
|
A |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
|
rs202208566
|
|
|
0.700 |
GeneticVariation |
UNIPROT |
|
|
|
|
rs367807476
|
|
|
0.700 |
GeneticVariation |
UNIPROT |
|
|
|
|
rs372481703
|
|
|
0.700 |
GeneticVariation |
UNIPROT |
|
|
|
|
rs555607708
|
|
A |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
|
rs587780537
|
|
A |
0.700 |
GeneticVariation |
CLINVAR |
|
|
|
|
rs11655237
|
|
|
0.010 |
GeneticVariation |
BEFREE |
<b>Conclusion:</b> Our results indicate that LINC00673 rs11655237 is associated with an increased GC risk, possibly by down-regulating LINC00673 expression through creating a miR-1231 binding site.
|
31118802 |
2019 |
|
rs16901946
|
|
|
0.020 |
GeneticVariation |
BEFREE |
<b>Conclusions:</b> Our study suggested that rs16</span>901946 G allele carriers have an increased risk of gastric cancer, and the risk could be enhanced by the interactions between the polymorphism and age, sex, <i>Helicobacter pylori</i> infection.
|
28367233 |
2017 |
|
rs1800625
|
|
|
0.010 |
GeneticVariation |
BEFREE |
<b>Conclusions:</b><i>RAGE</i> gene SNP rs1800625 was significantly associated with gastric cancer risk, and rs1800625 and rs184003 were related to tumor clinical stage, indicating that <i>RAGE</i> gene may be a gastric cancer-susceptibility gene.
|
30719146 |
2019 |
|
rs184003
|
|
|
0.020 |
GeneticVariation |
BEFREE |
<b>Conclusions:</b><i>RAGE</i> gene SNP rs1800625 was significantly associated with gastric cancer risk, and rs1800625 and rs184003 were related to tumor clinical stage, indicating that <i>RAGE</i> gene may be a gastric cancer-susceptibility gene.
|
30719146 |
2019 |
|
rs1062935
|
|
|
0.010 |
GeneticVariation |
BEFREE |
<b>Results:</b> The single-locus analysis indicated that <i>RPTOR</i> rs1062935 T>C was associated with an increased risk of poor GC prognosis (CC vs. TT/TC: adjusted Hazard ratio (HR) = 1.71, 95% confidence interval (CI) = 1.04-2.82).
|
29721055 |
2018 |
|
rs77447679
|
|
|
0.010 |
GeneticVariation |
BEFREE |
<i>Conclusion</i>: This study revealed that CBX4 rs7</span>7447679 polymorphism was positively associated with GC, and individuals with CC genotype had less risk of GC.
|
29158794 |
2017 |
|
rs2297518
|
|
|
0.020 |
GeneticVariation |
BEFREE |
<i>iNOS</i> rs2297518 and <i>eNOS</i> rs2070744 polymorphisms may represent susceptible factors for gastric cancer.
|
29765229 |
2018 |
|
rs2070744
|
|
|
0.010 |
GeneticVariation |
BEFREE |
<i>iNOS</i> rs2297518 and <i>eNOS</i> rs2070744 polymorphisms may represent susceptible factors for gastric cancer.
|
29765229 |
2018 |
|
rs1051690
|
|
|
0.010 |
GeneticVariation |
BEFREE |
<i>INSR</i> rs1051690 SNP is associated with increased risk of GC, while polymorphisms in <i>IL12B</i>, <i>CCND1</i> and <i>IL10</i> genes are not linked with the presence of GC.
|
28596683 |
2017 |
|
rs2293303
|
|
|
0.010 |
GeneticVariation |
BEFREE |
4.87, 2.72-8.71 for rs2293303).We further investigated if these tSNPs were related to the S5y of gastric cancer, and the results displayed that only the SNP rs4135385 AG/AA genotypes were significantly associated with a favorable gastric cancer survival compared with the GG genotype [adjusted hazard ratio (HR) = 0.80, 95% CI = 0.66-0.97], and the association was more prominent among patients with non-cardia gastric cancer (NCGC) than those with cardia gastric cancer (CGC) (Log-rank P = 0.007 for NCGC and 0.417 for CGC).
|
22848100 |
2012 |
|
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
5-fluorouracil (5-Fu) metabolism associated enzyme, methylenetetrahydrofolate reductase (MTHFR)'s polymorphism C677T can affect enzyme activity and a series of studies have been performed to examine the association of this MTHFR polymorphism with the clinical outcomes of gastric cancer (GC) patients treated with 5-Fu based chemotherapies.
|
29581785 |
2018 |
|
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
C677T, A1298C and G1793A) and their haplotypes are associated with the risk of gastric cancer.
|
15643524 |
2005 |
|
rs779315943
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The DNMT3A -448A>G polymorphism is a novel functional SNP and contributes to its genetic susceptibility to GC.
|
20128888 |
2010 |
|
rs4880
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Val(16)Ala polymorphism is related to gastric cancer development.
|
20233853 |
2010 |