|
rs3918226
|
|
T |
0.700 |
GeneticVariation |
GWASCAT |
A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease.
|
26343387 |
2015 |
|
rs3918226
|
|
T |
0.700 |
GeneticVariation |
GWASCAT |
Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.
|
29212778 |
2018 |
|
rs3918226
|
|
T |
0.700 |
GeneticVariation |
GWASCAT |
Association analyses based on false discovery rate implicate new loci for coronary artery disease.
|
28714975 |
2017 |
|
rs3918226
|
|
T |
0.700 |
GeneticVariation |
GWASCAT |
Efficiently controlling for case-control imbalance and sample relatedness in large-scale genetic association studies.
|
30104761 |
2018 |
|
rs1799983
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We recently identified two endothelial nitric oxide synthase (eNOS) gene polymorphisms, Glu298Asp and T-786-->C, which are independently associated with coronary spasm. eNOS gene intron 4b/a polymorphism is also reported to be involved in smoking-dependent coronary artery disease.
|
10979242 |
2000 |
|
rs1799983
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The genotype frequencies for Glu298/Asp (Glu/Glu and Glu/Asp) genotypes were 75% and 25% in CAD subjects and 88% and 12% in control subjects, respectively.
|
22045428 |
2011 |
|
rs1799983
|
|
|
0.100 |
GeneticVariation |
BEFREE |
On the basis of present results, it can be concluded that rs1799</span>983 is strongly associated with coronary artery disease in our population and TT genotype of this polymorphism enhanced the risk of coronary artery disease in Pakistani population.
|
25057159 |
2015 |
|
rs1799983
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Homozygosity for a common NOS 3 polymorphism (894 G-->T) which encodes a Glu298-->Asp amino acid substitution in eNOS is a risk factor for angiographic CAD and recent MI in this population.
|
10510054 |
1999 |
|
rs1799983
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We performed multiple logistic regression analysis for the effect of the T(-786)C, the missense Glu298Asp variant, and other coronary risk factors on two- and three-vessel CAD.
|
12651036 |
2003 |
|
rs1799983
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Lack of association of the Glu298Asp polymorphism of endothelial nitric oxide synthase with manifest coronary artery disease, carotid atherosclerosis and forearm vascular reactivity in two Austrian populations.
|
12641536 |
2003 |
|
rs1799983
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Further subgroup analyses according to ethnicity of participants revealed that the rs1799983 and rs2070744 polymorphisms were significantly associated with the risk of coronary artery disease in both Caucasians and Asians, whereas the rs869109213 polymorphism was only associated with the risk of coronary artery disease in Caucasians.
|
30789045 |
2019 |
|
rs1799983
|
|
|
0.100 |
GeneticVariation |
BEFREE |
In conclusion, we confirmed that the eNOS G894T polymorphism is a risk factor for premature CAD, particularly in those suffering premature MI.
|
29100441 |
2017 |
|
rs1799983
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Glu298Asp polymorphism of the endothelial nitric oxide synthase (eNOS) gene (NOS3) has been characterized as a risk factor of hypertension and coronary artery disease.
|
21816783 |
2011 |
|
rs1799983
|
|
|
0.100 |
GeneticVariation |
BEFREE |
A missense mutation of the nitric oxide synthase (eNOS) gene (Glu298Asp) in five patients with coronary artery disease--case reports.
|
10451235 |
1999 |
|
rs1799983
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The synthesis of available evidence supports the fact that eNOS G894T andT-786C are associated with CAD.
|
20861627 |
2010 |
|
rs1799983
|
|
|
0.100 |
GeneticVariation |
BEFREE |
This study, for the first time, suggests an independent association of 894G>T and -786T>C polymorphisms of endothelial nitric oxide synthase gene with coronary artery disease in a Saudi population.
|
20470943 |
2010 |
|
rs1799983
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Association between the endothelial nitric oxide synthase gene Glu298Asp polymorphism and coronary heart disease: a meta‑analysis of 39 case‑control studies.
|
23443250 |
2013 |
|
rs1799983
|
|
|
0.100 |
GeneticVariation |
BEFREE |
NO level and endothelial NO synthase gene polymorphism (Glu298Asp) in the patients with coronary artery disease from the Turkish population.
|
15483745 |
2004 |
|
rs1799983
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Effects of eNOS rs1799983 and ACE rs4646994 polymorphisms on the therapeutic efficacy of salvianolate injection in Chinese patients with coronary heart disease.
|
24827774 |
2014 |
|
rs1799983
|
|
|
0.100 |
GeneticVariation |
BEFREE |
However, there was evidence that small studies with more striking results could affect the associations of the Glu298Asp and -786T>C polymorphisms with coronary heart disease.
|
17018701 |
2006 |
|
rs1799983
|
|
|
0.100 |
GeneticVariation |
BEFREE |
To determine if the NOS3 genetic variants are associated with CAD in the Han Chinese, we examined the potential association between C</span>AD and eight single nucleotide polymorphisms (rs1799983, rs2070744, rs11771443, rs3918188, rs2853796, rs7830, rs1541861, and rs2853792) of the NOS3 using the MassARRAY system.
|
27323132 |
2016 |
|
rs1799983
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Polymorphisms in the endothelial nitric oxide synthase ( eNOS ) gene (- 786T > C and 894G > T ) enhance endothelial dysfunction and have been studied in relation to coronary artery disease (CAD).
|
20846926 |
2010 |
|
rs1799983
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Polymorphisms in the endothelial nitric oxide synthase (eNOS) gene (-786T>C, 4a4b, and 894G>T) have been previously associated with increased CAD risk.
|
26662450 |
2015 |
|
rs1799983
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The present study provides evidence that the Glu(298)-->Asp and T(786)-->C polymorphisms of the eNOS gene are associated with the presence and severity of angiographically defined CAD in the Italian population and that those individuals carrying both eNOS variants simultaneously might have a higher risk of developing CAD.
|
12600950 |
2003 |
|
rs1799983
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The results of present study revealed that eNOS G894T polymorphism is associated with increased risk of CAD in our population.
|
21602253 |
2012 |