|
rs3918226
|
|
T |
0.700 |
GeneticVariation |
GWASCAT |
Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.
|
29212778 |
2018 |
|
rs3918226
|
|
T |
0.700 |
GeneticVariation |
GWASCAT |
Efficiently controlling for case-control imbalance and sample relatedness in large-scale genetic association studies.
|
30104761 |
2018 |
|
rs3918226
|
|
T |
0.700 |
GeneticVariation |
GWASCAT |
Association analyses based on false discovery rate implicate new loci for coronary artery disease.
|
28714975 |
2017 |
|
rs3918226
|
|
T |
0.700 |
GeneticVariation |
GWASCAT |
A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease.
|
26343387 |
2015 |
|
rs1799983
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Further subgroup analyses according to ethnicity of participants revealed that the rs1799983 and rs2070744 polymorphisms were significantly associated with the risk of coronary artery disease in both Caucasians and Asians, whereas the rs869109213 polymorphism was only associated with the risk of coronary artery disease in Caucasians.
|
30789045 |
2019 |
|
rs1799983
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Our findings show that the 27-bp VNTR polymorphic locus, but not the c.894G>T polymorphic locus, is associated with CAD and that it may regulate NOS3 pre-mRNA splicing in a length-dependent manner.
|
30447355 |
2019 |
|
rs1799983
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The association between the <i>NOS3</i> rs1799983 polymorphism and CAD may be partly mediated by abnormal NO and lipid levels caused by the T allele.
|
31138610 |
2019 |
|
rs1799983
|
|
|
0.100 |
GeneticVariation |
BEFREE |
In addition, we also found that the rs1799983 polymorphism was significantly associated with the susceptibility to peripheral artery disease, whereas the rs2070744 polymorphism was significantly associated with the susceptibility to coronary artery disease in DM patients.
|
30140993 |
2018 |
|
rs1799983
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Moreover, the odds ratio for CAD related to the G894T (OR=1.09, 95% CI=(0.60-2.00), T-786C (OR=1.04, 95% CI=(0.57-1.89) and 4a/4b (OR=1.75, 95% CI=(0.92-3.32) variants did not show statistical significance.
|
30788304 |
2018 |
|
rs1799983
|
|
|
0.100 |
GeneticVariation |
BEFREE |
In conclusion, we confirmed that the eNOS G894T polymorphism is a risk factor for premature CAD, particularly in those suffering premature MI.
|
29100441 |
2017 |
|
rs1799983
|
|
|
0.100 |
GeneticVariation |
BEFREE |
In conclusion, although Glu298Asp did not show association with CAD and lipid profile in the studied cohort, it may exert its effect through blood pressure; however, the mechanism of this effect needs to be explored in the future.
|
28620990 |
2017 |
|
rs1799983
|
|
|
0.100 |
GeneticVariation |
BEFREE |
To determine if the NOS3 genetic variants are associated with CAD in the Han Chinese, we examined the potential association between C</span>AD and eight single nucleotide polymorphisms (rs1799983, rs2070744, rs11771443, rs3918188, rs2853796, rs7830, rs1541861, and rs2853792) of the NOS3 using the MassARRAY system.
|
27323132 |
2016 |
|
rs1799983
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Genetic polymorphisms of eNOS (-786T/C, Intron 4b/4a & 894G/T) and its association with asymptomatic first degree relatives of coronary heart disease patients.
|
27613099 |
2016 |
|
rs1799983
|
|
|
0.100 |
GeneticVariation |
BEFREE |
On the basis of present results, it can be concluded that rs1799</span>983 is strongly associated with coronary artery disease in our population and TT genotype of this polymorphism enhanced the risk of coronary artery disease in Pakistani population.
|
25057159 |
2015 |
|
rs1799983
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Polymorphisms in the endothelial nitric oxide synthase (eNOS) gene (-786T>C, 4a4b, and 894G>T) have been previously associated with increased CAD risk.
|
26662450 |
2015 |
|
rs1799983
|
|
|
0.100 |
GeneticVariation |
BEFREE |
These findings suggest that the G894T (rs1799983) polymorphism of the eNOS gene was associated with CAD in Tunisian patients.
|
25748584 |
2015 |
|
rs1799983
|
|
|
0.100 |
GeneticVariation |
BEFREE |
AF patients with rs1799983 variants were more likely to have coronary artery disease or stroke than those without genetic variant at this gene (31.0% vs. 17.3%, p=0.004).
|
26256966 |
2015 |
|
rs1799983
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Effects of eNOS rs1799983 and ACE rs4646994 polymorphisms on the therapeutic efficacy of salvianolate injection in Chinese patients with coronary heart disease.
|
24827774 |
2014 |
|
rs1799983
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Glu298Asp, T786-C and 27 bp VNTR b/a) with CAD.
|
25409023 |
2014 |
|
rs1799983
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Association between the endothelial nitric oxide synthase gene Glu298Asp polymorphism and coronary heart disease: a meta‑analysis of 39 case‑control studies.
|
23443250 |
2013 |
|
rs1799983
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Genotype and allele distributions of G894T and intron 4a/b polymorphisms were not significantly different between T2DM subjects with and without CAD/MI.
|
23182401 |
2013 |
|
rs1799983
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The results of present study revealed that eNOS G894T polymorphism is associated with increased risk of CAD in our population.
|
21602253 |
2012 |
|
rs1799983
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The G894T polymorphism on endothelial nitric oxide synthase gene is associated with increased coronary heart disease among Asia population: evidence from a Meta analysis.
|
22417945 |
2012 |
|
rs1799983
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The present study was conducted to investigate the possible outcome of interaction between endothelial nitric oxide (NOS3) G894T and cholesteryl ester transfer TaqIB variants on the risk of coronary artery disease (CAD) and type 2 diabetes mellitus (T2DM).
|
23157875 |
2012 |
|
rs1799983
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The genotype frequencies for Glu298/Asp (Glu/Glu and Glu/Asp) genotypes were 75% and 25% in CAD subjects and 88% and 12% in control subjects, respectively.
|
22045428 |
2011 |