rs1057518923
|
|
GC |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
rs112417755
|
|
C |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
rs138924661
|
|
A |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
rs373909351
|
|
A |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
rs398123538
|
|
C |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
rs777476179
|
|
T |
0.700 |
GeneticVariation |
CLINVAR |
|
|
|
rs699
|
|
|
0.090 |
GeneticVariation |
BEFREE |
There was no interaction between age of onset of ESRF and either the angiotensinogen M235T allele or angiotensin 1 receptor A1166C polymorphism.
|
9291178 |
1997 |
rs1267969615
|
|
|
0.060 |
GeneticVariation |
BEFREE |
There was no interaction between age of onset of ESRF and either the angiotensinogen M235T allele or angiotensin 1 receptor A1166C polymorphism.
|
9291178 |
1997 |
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The genotype of the MTHFR gene in 106 patients with ESRD was homozygous C677T mutation (VV) in 17 patients (16.1%) and heterozygous (AV) in 63 patients (58.4%); 26 patients (24.5%) did not carry this mutation (AA).
|
10430972 |
1999 |
rs699
|
|
|
0.090 |
GeneticVariation |
BEFREE |
Angiotensin I-converting enzyme gene insertion/deletion and angiotensinogen M235T polymorphisms: risk of chronic renal failure. End-Stage Renal Disease Study Group.
|
10916074 |
2000 |
rs1267969615
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Angiotensin I-converting enzyme gene insertion/deletion and angiotensinogen M235T polymorphisms: risk of chronic renal failure. End-Stage Renal Disease Study Group.
|
10916074 |
2000 |
rs145640112
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In addition, an A716C polymorphism in exon 7 resulting in the amino acid change H189P in the A3 domain of the heavy chain was observed in 5 patients belonging to 3 ESRD families.
|
11031105 |
2000 |
rs4253373
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Individually or combined, the allelic variants observed are not statistically associated with ESRD, though in several cases (e.g., H183Q) the small number of people in the population carrying these alleles limits our ability to statistically test for significant association with ESRD.
|
11031105 |
2000 |
rs752390951
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In addition, an A716C polymorphism in exon 7 resulting in the amino acid change H189P in the A3 domain of the heavy chain was observed in 5 patients belonging to 3 ESRD families.
|
11031105 |
2000 |
rs760452842
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In addition, an A716C polymorphism in exon 7 resulting in the amino acid change H189P in the A3 domain of the heavy chain was observed in 5 patients belonging to 3 ESRD families.
|
11031105 |
2000 |
rs1799983
|
|
|
0.100 |
GeneticVariation |
BEFREE |
In addition, a mutation, Glu298Asp, in exon 7 of NOS3 and a 27 bp variable number tandem repeat (VNTR) marker in intron 4 of NOS3 were evaluated in the sibling pairs and in an additional 92 unrelated African-Americans with type 2 diabetes mellitus-associated ESRD (singletons).
|
11071967 |
2000 |
rs699
|
|
|
0.090 |
GeneticVariation |
BEFREE |
There was no association between age at onset of ESRD and either M235T or A1166C polymorphism.
|
11136175 |
2001 |
rs1267969615
|
|
|
0.060 |
GeneticVariation |
BEFREE |
There was no association between age at onset of ESRD and either M235T or A1166C polymorphism.
|
11136175 |
2001 |
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The C677T mutation of the MTHFR gene may be an independent risk factor that predicts the development of carotid atherosclerosis in ESRD patients.
|
11287760 |
2001 |
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The C677T genotype of MTHFR is associated with CVD in ESRD and may be a more meaningful marker than tHcy for abnormal homocysteine metabolism in ESRD.
|
11532106 |
2001 |
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
To evaluate the respective roles of residual glomerular filtration (by measuring a specific protein marker, cystatin C), genetic polymorphisms and nutritional status in tHcy blood levels in end-stage renal disease patients (ESRD) under hemodialysis and supplemented with folate, we measured tHcy, folate, vitamin B12 (B12), creatinine, cystatin C, albumin and C-reactive protein and determined the polymorphism of methylenetetrahydrofolate reductase (MTHFR) (C677T and A1289C) and of methionine synthase (MS) (A2756G) in 114 ESRD patients before hemodialysis and 76 control subjects.
|
11592445 |
2001 |
rs1805087
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To evaluate the respective roles of residual glomerular filtration (by measuring a specific protein marker, cystatin C), genetic polymorphisms and nutritional status in tHcy blood levels in end-stage renal disease patients (ESRD) under hemodialysis and supplemented with folate, we measured tHcy, folate, vitamin B12 (B12), creatinine, cystatin C, albumin and C-reactive protein and determined the polymorphism of methylenetetrahydrofolate reductase (MTHFR) (C677T and A1289C) and of methionine synthase (MS) (A2756G) in 114 ESRD patients before hemodialysis and 76 control subjects.
|
11592445 |
2001 |
rs370819889
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To evaluate the respective roles of residual glomerular filtration (by measuring a specific protein marker, cystatin C), genetic polymorphisms and nutritional status in tHcy blood levels in end-stage renal disease patients (ESRD) under hemodialysis and supplemented with folate, we measured tHcy, folate, vitamin B12 (B12), creatinine, cystatin C, albumin and C-reactive protein and determined the polymorphism of methylenetetrahydrofolate reductase (MTHFR) (C677T and A1289C) and of methionine synthase (MS) (A2756G) in 114 ESRD patients before hemodialysis and 76 control subjects.
|
11592445 |
2001 |
rs5443
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The results of our study suggest that GNB3 C825T polymorphism does not contribute substantially to the increased risk of the development of ESRD.
|
11684796 |
2002 |
rs1799983
|
|
|
0.100 |
GeneticVariation |
BEFREE |
In conclusion, the frequent Glu298Asp polymorphism of ENOS is associated with a 5 year lower mean age at ESRD in this subset of ADPKD males.
|
11823442 |
2002 |