|
rs10137082
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Genotyping analysis demonstrated that 2 SNPs among 13 were significantly associated with ESRD after adjusting for age and sex, which were shown by IL17E rs10137082 (odds ratio (OR) 1.48 in codominant 1, OR 1.54 in dominant, OR 1.47 in log-additive) and IL17RA rs4819554 (OR 1.46 in codominant 1, OR 1.79 in codominant 2, OR 1.54 in dominant, OR 1.39 in log-additive).
|
23147652 |
2012 |
|
rs1020608562
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We explored the role of CCR5-Δ32, CCR5-G59029A, CX3CR1 V249I and T280M gene polymorphisms as susceptibility for end stage renal disease (ESRD).
|
21132346 |
2011 |
|
rs1024611
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The objective of the present study is to evaluate the association, if any, of g.-2518A>G polymorphism (rs1024611) in MCP-1 gene in T2D cases with and without ESRD in the population of Punjab from North-West India.
|
25154422 |
2015 |
|
rs1033182
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The most significant association with type 2 diabetes-ESRD was with rs1033182 in intron 2 (P = 0.013, admixture-adjusted P(a) = 0.021).
|
17327435 |
2007 |
|
rs10404257
|
|
|
0.010 |
GeneticVariation |
BEFREE |
SNPs were tested for interaction with markers in the APOL1 gene, previously associated with non-DM ESRD in AAs, and rs10404257 was modestly associated (p = 0.0261, additive model).
|
22965004 |
2012 |
|
rs1042636
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We genotyped the CaSR R990G and Q1011E variants in 192 end-stage renal disease (ESRD) patients by allele-specific PCR.
|
19640368 |
2009 |
|
rs1042636
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Our results suggest that CaR gene polymorphism (codon G990R) influences the responsiveness of the parathyroid gland to changes of extracellular Ca2+ in ESRD patients.
|
11863123 |
2002 |
|
rs1042713
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We extended our findings to an independent case/control sample of Black hypertensive ESRD, in which we found that variant Gly16Arg that tagged the GFR slope-determining ADRB2 haplotype also conferred risk for the ESRD trait in Blacks.
|
20484896 |
2010 |
|
rs1044498
|
|
|
0.010 |
GeneticVariation |
BEFREE |
However, the extensively studied K121Q variant (rs1044498) did not reveal evidence for association with type 2 diabetic ESRD in this African-American population.
|
18184924 |
2008 |
|
rs1045642
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The purpose of this study is to compare the genotype frequency of C3435T and G1199A polymorphisms in MDR1 between ESRD patients and healthy controls in the Chinese population to determine whether the alteration of the P-gp function is associated with ESRD.
|
17376299 |
2007 |
|
rs104894833
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In addition, our results underscore the high prevalence of not only undiagnosed Fabry patients but functional variants of p.E66Q among the ESRD population.
|
22695894 |
2012 |
|
rs1049255
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our results suggested that rs1049255 polymorphism of CYBA modified the risk of ESRD (p = 0.019; OR = 0.625; 95%CI = 0.424-0.921).
|
26627442 |
2016 |
|
rs1057518923
|
|
GC |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
|
rs1061170
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Multivariate logistic regression analysis showed that Y402H genotype was independently associated with cardiovascular comorbidity in ESRD patients.
|
19428307 |
2009 |
|
rs10808565
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We further identified a common haplotype containing the C allele at rs10808565 and the A allele at rs13447075 that was associated with ESRD (P = 0.003).
|
17881614 |
2007 |
|
rs10887800
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Distribution of genotypes and frequencies of alleles of rs10887800 polymorphism were compared in the following subgroups of patients: ESRD HY + (n = 278) and ESRD HY - (n = 143).
|
21617193 |
2012 |
|
rs10951982
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The other three SNPs (rs10951982, rs6954996, and rs9374), in all comparison models, were not associated with ESRD risk (P > 0.05).
|
26841219 |
2016 |
|
rs11089781
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Stratifying by APOL1 risk genotype (recessive) and adjusting for African ancestry identified a significant additive association between rs11089781 and ESKD in each stratum and in a meta-analysis [meta-analysis P = 0.0070; odds ratio (OR) = 1.29]; ORs were consistent across APOL1 risk strata.
|
28339911 |
2018 |
|
rs11089788
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Based on a large Chinese IgAN cohort, we found an association between rs11089788 and prognosis of IgAN, adding to the mounting evidence of MYH9 as an important gene in IgAN to ESRD.
|
21245129 |
2011 |
|
rs112417755
|
|
C |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
|
rs115489112
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Two additional variants (H800R and Y1174H) were nominally associated with protection from end stage renal disease (P=0.036; odds ratio, 0.44; P=0.0084; odds ratio, 0.040, respectively) in the locus-wide single-variant association tests.
|
24948143 |
2014 |
|
rs11571317
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The present study was designed to investigate the impact of CTLA-4+49 A>G (rs231775), -318 C>T (rs5742909), -658 C>T (rs11571317), -1147 C>T (rs16840252), -1661 A>G (rs4553808), +6230 A>G (rs3087243) SNPs, and microsatellite (AT)n repeat polymorphism among end-stage renal disease (ESRD), acute allograft rejection (AR), and delayed graft function (DGF) cases.
|
24313821 |
2014 |
|
rs11614913
|
|
|
0.010 |
GeneticVariation |
BEFREE |
These results suggest that the variants of MicroRNA SNPs, namely, rs2910164, rs11614913, and rs3746444, might be involved in susceptibility to ESRD and AR.
|
24978643 |
2014 |
|
rs1162592300
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The -174G/C polymorphism of the IL-6 gene and the chemokine receptor CX3CR1 polymorphisms 249V/I and 280T/M were examined for their association with cardiovascular abnormalities in a cohort of 161 patients with end-stage renal disease (ESRD) treated by hemodialysis.
|
12846758 |
2003 |
|
rs11643718
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The SLC12A3-Arg913Gln variation may be associated with increased blood pressure and UAER and, therefore, could be used to predict the development and progression of DN-ESRD in Chinese T2DM patients undergoing hemodialysis.
|
28744814 |
2018 |