|
rs1024611
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The objective of the present study is to evaluate the association, if any, of g.-2518A>G polymorphism (rs1024611) in MCP-1 gene in T2D cases with and without ESRD in the population of Punjab from North-West India.
|
25154422 |
2015 |
|
rs12137135
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Five genetic loci (WNT4/ZBTB40-rs12137135, RGMA/MCTP2-rs17709344, MAPRE1P2-rs1670754, SEMA6D/SLC24A5-rs12917114 and SIK1-rs2838302) were associated with ESRD in the FinnDiane study.
|
24871321 |
2014 |
|
rs12197043
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Also, two intergenic SNPs showed consistent genotypic association with T2DM-ESRD: rs12197043 and rs4897081.
|
18560894 |
2008 |
|
rs12513649
|
|
|
0.010 |
GeneticVariation |
BEFREE |
CREBRF rs12513649 and rs373863828 were genotyped in 2022 participants in a community-based cross-sectional study designed to identify determinants of diabetes and end-stage renal disease (ESRD).
|
31280340 |
2019 |
|
rs12917114
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Five genetic loci (WNT4/ZBTB40-rs12137135, RGMA/MCTP2-rs17709344, MAPRE1P2-rs1670754, SEMA6D/SLC24A5-rs12917114 and SIK1-rs2838302) were associated with ESRD in the FinnDiane study.
|
24871321 |
2014 |
|
rs1670754
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Five genetic loci (WNT4/ZBTB40-rs12137135, RGMA/MCTP2-rs17709344, MAPRE1P2-rs1670754, SEMA6D/SLC24A5-rs12917114 and SIK1-rs2838302) were associated with ESRD in the FinnDiane study.
|
24871321 |
2014 |
|
rs4897081
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Also, two intergenic SNPs showed consistent genotypic association with T2DM-ESRD: rs12197043 and rs4897081.
|
18560894 |
2008 |
|
rs730947
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Variant rs730947 in the GCK1 gene appears to play a role in early ESRD onset in African Americans.
|
20144192 |
2010 |
|
rs743811
|
|
|
0.010 |
GeneticVariation |
BEFREE |
HMOX1 rs743811 associated with chronic kidney disease stage (OR=3.0, P=0.0001) in the University of Illinois cohort and end-stage renal disease (OR=10.0, P=0.0003) in the Walk-Treatment of Pulmonary Hypertension and Sickle cell Disease with Sildenafil Therapy cohort.
|
26206798 |
2015 |
|
rs7652589
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This study shows that the A allele of rs7652589 is a risk allele for nephrolithiasis-related ESRD.
|
27739473 |
2016 |
|
rs77113398
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Following extension analyses in 1910 non-diabetic ESKD cases and 908 non-diabetic non-nephropathy controls, a meta-analysis of 5342 AA all-cause ESKD cases and 6977 AA non-diabetic non-nephropathy controls revealed an additional novel all-cause ESKD locus at EFNB2 (rs77113398; P = 9.84 × 10<sup>-9</sup>; OR = 1.94).
|
31092297 |
2019 |
|
rs8014363
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The minor allele in NPHS2 markedly changed the APOL1-ESKD association odds ratio (OR) from 7.03 to 1.76 (∼50% reduction in effect per copy of the minor allele), rs2802723 changed the OR from 5.1 to 10.5, and rs8014363 increased the OR from 4.8 to 9.5.
|
24157943 |
2014 |
|
rs1045642
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The purpose of this study is to compare the genotype frequency of C3435T and G1199A polymorphisms in MDR1 between ESRD patients and healthy controls in the Chinese population to determine whether the alteration of the P-gp function is associated with ESRD.
|
17376299 |
2007 |
|
rs2229109
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The purpose of this study is to compare the genotype frequency of C3435T and G1199A polymorphisms in MDR1 between ESRD patients and healthy controls in the Chinese population to determine whether the alteration of the P-gp function is associated with ESRD.
|
17376299 |
2007 |
|
rs1267969615
|
|
|
0.060 |
GeneticVariation |
BEFREE |
There was no interaction between age of onset of ESRF and either the angiotensinogen M235T allele or angiotensin 1 receptor A1166C polymorphism.
|
9291178 |
1997 |
|
rs1267969615
|
|
|
0.060 |
GeneticVariation |
BEFREE |
This study was designed to evaluate the angiotensin-converting enzyme insertion/deletion (ACE-I/D), angiotensinogen (AGT) M235T, and angiotensin II receptor type 1 (ATR1) A1166C and type 2 (ATR2) C3123A gene polymorphisms as risk factors for progression to ESRD in patients with VUR.Methods.
|
19288324 |
2009 |
|
rs1267969615
|
|
|
0.060 |
GeneticVariation |
BEFREE |
We studied retrospectively the role of angiotensinogen (AGT) M235T, angiotensin converting enzyme (ACE) insertion/deletion (I/D), angiotensin II type 1 receptor (AT1R) A1166C, aldosterone syntase (CYP11B2) -344C/T and intron 2 W/C polymorphisms in conjunction with clinical and biochemical covariables on the rate of progression of renal insufficiency in a group of patients with ESRD of various etiologies.
|
12832734 |
2003 |
|
rs1267969615
|
|
|
0.060 |
GeneticVariation |
BEFREE |
There was no association between age at onset of ESRD and either M235T or A1166C polymorphism.
|
11136175 |
2001 |
|
rs1267969615
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Angiotensin I-converting enzyme gene insertion/deletion and angiotensinogen M235T polymorphisms: risk of chronic renal failure. End-Stage Renal Disease Study Group.
|
10916074 |
2000 |
|
rs1267969615
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Two hundred and forty-six end-stage renal disease (ESRD) patients on peritoneal dialysis and 183 control subjects, all of Chinese origin, were genotyped for the ACE insertion/deletion (I/D) and the AGT M235T gene polymorphisms.
|
12675870 |
2003 |
|
rs867394500
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We studied retrospectively the role of angiotensinogen (AGT) M235T, angiotensin converting enzyme (ACE) insertion/deletion (I/D), angiotensin II type 1 receptor (AT1R) A1166C, aldosterone syntase (CYP11B2) -344C/T and intron 2 W/C polymorphisms in conjunction with clinical and biochemical covariables on the rate of progression of renal insufficiency in a group of patients with ESRD of various etiologies.
|
12832734 |
2003 |
|
rs10404257
|
|
|
0.010 |
GeneticVariation |
BEFREE |
SNPs were tested for interaction with markers in the APOL1 gene, previously associated with non-DM ESRD in AAs, and rs10404257 was modestly associated (p = 0.0261, additive model).
|
22965004 |
2012 |
|
rs4961
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We examined the influence of the ACE I/D polymorphism, adducin Trp460Gly polymorphism and the association of both polymorphisms on the progression of ADPKD towards end-stage renal failure (ESRF).
|
12697976 |
2003 |
|
rs4961
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The G460W polymorphism of ADD had no effect on the age at ESRD and cumulative renal survival, either alone or in combination with the ACE (I/D) polymorphism.
|
13679477 |
2003 |
|
rs1042713
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We extended our findings to an independent case/control sample of Black hypertensive ESRD, in which we found that variant Gly16Arg that tagged the GFR slope-determining ADRB2 haplotype also conferred risk for the ESRD trait in Blacks.
|
20484896 |
2010 |