Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1187393388
rs1187393388
MSH6 ; FBXO11
0.010 GeneticVariation BEFREE Specifically, our observation supports the association between the MSH6 c.2194C>T pathogenic variant and extracolonic tumours and it suggests that MSH6 pathogenic variants are associated with familial pancreatic cancer more frequently than assumed. 31851094

2020
dbSNP: rs587779930
rs587779930
MSH6 ; FBXO11
0.010 GeneticVariation BEFREE Specifically, our observation supports the association between the MSH6 c.2194C>T pathogenic variant and extracolonic tumours and it suggests that MSH6 pathogenic variants are associated with familial pancreatic cancer more frequently than assumed. 31851094

2020
dbSNP: rs63751127
rs63751127
MSH6 ; FBXO11
0.010 GeneticVariation BEFREE Specifically, our observation supports the association between the MSH6 c.2194C>T pathogenic variant and extracolonic tumours and it suggests that MSH6 pathogenic variants are associated with familial pancreatic cancer more frequently than assumed. 31851094

2020
dbSNP: rs4503083
rs4503083
IDO2
0.010 GeneticVariation BEFREE Familial pancreatic cancer was noted in 15 cases (19%) and comparison of the FPC cohort set to the genetic control set showed a 3-fold increase in Y359Stop homozygous rates (p = 0.054). 29426021

2018
dbSNP: rs1176026649
rs1176026649
PALLD ; CBR4
0.010 GeneticVariation BEFREE The P239S palladin variant has recently been suggested to play a role in hereditary pancreatic cancer. 17415588

2007
dbSNP: rs11571833
rs11571833
BRCA2
0.010 GeneticVariation BEFREE One K3326X carrier with familial pancreatic cancer</span> carried an alteration (IVS 16-2A>G) suspected to be deleterious. 15806175

2005
dbSNP: rs486907
rs486907
RNASEL
0.010 GeneticVariation BEFREE Our results suggest that RNASEL variants Glu265X and Arg462Gln may contribute to the tumorigenesis of sporadic and familial pancreatic cancer, which has to be proven in large scale studies. 15981205

2005
dbSNP: rs74315364
rs74315364
RNASEL
0.010 GeneticVariation BEFREE Our results suggest that RNASEL variants Glu265X and Arg462Gln may contribute to the tumorigenesis of sporadic and familial pancreatic cancer, which has to be proven in large scale studies. 15981205

2005
dbSNP: rs17107315
rs17107315
SPINK1
0.010 GeneticVariation BEFREE The SPINK1 N34S polymorphism was detected in 5 of 172 (2.9%) patients with chronic pancreatitis, in 4 of 200 (2.0%) patients with sporadic pancreatic adenocarcinoma, in 0 of 36 (0%) of patients with familial pancreatic cancer and in 3 of 177 (1.7%) controls of chronic cholecystitis. 14688470

2004