|
rs10475878
|
|
|
0.010 |
GeneticVariation |
BEFREE |
An additional 12 SNPs were associated with the PD phenotype at P ≤ 0.05 (APOE: rs405509, rs439401; TOMM40: rs8106922, and KIBRA: rs4320284, rs11740112, rs10040267, rs13171394, rs6555802, rs2241368, rs244904, rs6555805, and rs10475878).
|
30706571 |
2019 |
|
rs1048230
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To study the possible association of DMT1 gene with PD occurrence, one mutation (1303C/A) and two single nucleotide polymorphisms (SNPs) (1254T/C and IVS4+44C/A) in DMT1 gene were investigated in 192 PD patients in a Han Chinese population and 193 healthy controls by method of polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP).
|
21777657 |
2011 |
|
rs104886460
|
|
T |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
|
rs104893877
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The results revealed that 11 microRNAs were differently expressed in CSF, emphatically as miR-144-5p, miR-200a-3p and miR-542-3p, which were dramatically up-regulated in both A53T-transgenic mice and PD patients, and had a helpful accuracy for the PD prediction.
|
27965467 |
2017 |
|
rs104893877
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In the present study, the clinical characteristics of Parkinson's disease (PD) patients with Ala53Thr alpha-synuclein mutation (alpha-synPD) were compared with fPD patients without any known mutation.
|
12752402 |
2003 |
|
rs1056737920
|
|
|
0.700 |
GeneticVariation |
UNIPROT |
|
|
|
|
rs1064651
|
|
G |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
|
rs112176450
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The Asp620Asn mutation in the vacuolar protein sorting protein 35 (VPS35) gene and the Arg1205His mutation in the eukaryotic translation initiation factor 4 gamma 1 (EIF4G1) gene were identified in autosomal dominant late-onset familial and sporadic Parkinson disease (PD) patients in a Caucasian population.
|
23261770 |
2013 |
|
rs1130214
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Genetic variants of AKT1 have been shown to influence brain function of Parkinson's disease (PD) patients, and in this paper our aim is to investigate the association between the three single-nucleotide polymorphisms (rs2498799; rs2494732; rs1130214) and PD in Han Chinese.
|
27353512 |
2016 |
|
rs11564148
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Peripheral blood mononuclear cells (PBMCs) were collected from a clinically diagnosed 64-year old male Parkinson's disease (PD) patient with S1647T variant in the LRRK2 gene.
|
28395805 |
2017 |
|
rs121917767
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Ile93Met substitution was found neither in PD patients nor in controls.
|
12775255 |
2003 |
|
rs1237637353
|
|
G |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
|
rs12678719
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The same rs12678719-G AIP susceptibility allele was associated with lower levels of dopaminergic neuron related ligand binding in the contralateral putamen of PD patients (p = 0.026).
|
21947317 |
2012 |
|
rs1272596579
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The c.46G>T [p. Gly16Trp] variant in exon 1 was identified in a male PD patient, while a heterozygous frameshift variant, c.429delT [p. Val143ValfsX4], in exon 5 was found in an HC.
|
28455698 |
2018 |
|
rs1375532403
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The purpose of this study was to characterize the correlation between the Val158Met polymorphism in the COMT gene and the motor complication "wearing-off" in Chinese PD patients.
|
25108642 |
2014 |
|
rs1386483
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In the present case-control genetic association study we investigated whether panic disorder (PD) phenotypes are related to two single nucleotide polymorphisms (SNP) of TPH2, rs1386494 A/G and rs1386483 C/T.
|
17123728 |
2007 |
|
rs1386494
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In the present case-control genetic association study we investigated whether panic disorder (PD) phenotypes are related to two single nucleotide polymorphisms (SNP) of TPH2, rs1386494 A/G and rs1386483 C/T.
|
17123728 |
2007 |
|
rs144863268
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To study the possible association of DMT1 gene with PD occurrence, one mutation (1303C/A) and two single nucleotide polymorphisms (SNPs) (1254T/C and IVS4+44C/A) in DMT1 gene were investigated in 192 PD patients in a Han Chinese population and 193 healthy controls by method of polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP).
|
21777657 |
2011 |
|
rs1450426641
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A GBA p.Trp378Gly mutation was identified in two RBD and four PD patients (1% of all patients combined), and not in controls.
|
29920646 |
2018 |
|
rs145242123
|
|
|
0.700 |
GeneticVariation |
UNIPROT |
DNAJC13 genetic variants in parkinsonism.
|
25393719 |
2015 |
|
rs145242123
|
|
|
0.700 |
GeneticVariation |
UNIPROT |
DNAJC13 mutations in Parkinson disease.
|
24218364 |
2014 |
|
rs146930051
|
|
|
0.700 |
GeneticVariation |
UNIPROT |
DNAJC13 mutations in Parkinson disease.
|
24218364 |
2014 |
|
rs146930051
|
|
|
0.700 |
GeneticVariation |
UNIPROT |
DNAJC13 genetic variants in parkinsonism.
|
25393719 |
2015 |
|
rs150562946
|
|
|
0.700 |
GeneticVariation |
UNIPROT |
Parkin mutations and susceptibility alleles in late-onset Parkinson's disease.
|
12730996 |
2003 |
|
rs150562946
|
|
|
0.700 |
GeneticVariation |
UNIPROT |
Synaptotagmin-11 is a critical mediator of parkin-linked neurotoxicity and Parkinson's disease-like pathology.
|
29311685 |
2018 |