TPH2, tryptophan hydroxylase 2, 121278

N. diseases: 137; N. variants: 37
Source: ALL
Disease Type Disease Class Semantic Type N. genes d N. SNPs d Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
CUI: C1445957
Disease: Serum total cholesterol measurement
Serum total cholesterol measurement 		phenotype Laboratory Procedure 486 1243 0.100 None 1.000 1 1 2012 2012
CUI: C0233523
Disease: Antisocial behavior
Antisocial behavior 		phenotype Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms Mental or Behavioral Dysfunction 51 17 0.010 None 1.000 1 2012 2012
CUI: C1449563
Disease: Cardiomyopathy, Familial Idiopathic
Cardiomyopathy, Familial Idiopathic 		disease Cardiovascular Diseases Disease or Syndrome 773 243 0.010 None 1.000 1 2012 2012
CUI: C0564567
Disease: Impulsive character (finding)
Impulsive character (finding) 		phenotype Mental or Behavioral Dysfunction 52 19 0.010 None 1.000 1 1 2012 2012
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure 		disease Cardiovascular Diseases Disease or Syndrome 1760 165 0.010 None 1.000 1 2012 2012
CUI: C1535926
Disease: Neurodevelopmental Disorders
Neurodevelopmental Disorders 		group Mental Disorders Mental or Behavioral Dysfunction 535 14 0.010 None 1.000 1 2012 2012
CUI: C0028754
Disease: Obesity
Obesity 		disease Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases Disease or Syndrome 2821 1111 0.010 None 1.000 1 2012 2012
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		disease Immune System Diseases; Nervous System Diseases Disease or Syndrome 1800 1022 0.010 None 1.000 1 1 2012 2012
CUI: C0852733
Disease: Completed Suicide
Completed Suicide 		phenotype Mental or Behavioral Dysfunction 33 33 0.060 None 0.833 6 2004 2013
CUI: C0030319
Disease: Panic Disorder
Panic Disorder 		disease Mental Disorders Mental or Behavioral Dysfunction 175 101 0.050 None 1.000 5 8 2006 2013
CUI: C0011573
Disease: Endogenous depression
Endogenous depression 		disease Mental Disorders Mental or Behavioral Dysfunction 53 0.500 None 1.000 3 2007 2013
CUI: C0232600
Disease: Self-induced vomiting
Self-induced vomiting 		disease Pathological Conditions, Signs and Symptoms Mental or Behavioral Dysfunction 4 1 0.020 None 1.000 2 1 2011 2013
CUI: C0013473
Disease: Eating Disorders
Eating Disorders 		group Mental Disorders Mental or Behavioral Dysfunction 133 42 0.020 None 1.000 2 1 2011 2013
CUI: C0038441
Disease: Stress Disorders, Traumatic
Stress Disorders, Traumatic 		group Mental Disorders Mental or Behavioral Dysfunction 20 0.010 None 1.000 1 2013 2013
CUI: C0011351
Disease: Dental Enamel Hypoplasia
Dental Enamel Hypoplasia 		disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Stomatognathic Diseases Disease or Syndrome 72 1 0.010 None 1.000 1 2013 2013
CUI: C2169806
Disease: recurrent muscle twitches (symptom)
recurrent muscle twitches (symptom) 		phenotype Pathological Conditions, Signs and Symptoms; Nervous System Diseases Sign or Symptom 26 7 0.010 None 1.000 1 2 2013 2013
CUI: C0024523
Disease: Malabsorption Syndrome
Malabsorption Syndrome 		group Digestive System Diseases; Nutritional and Metabolic Diseases Disease or Syndrome 239 0.010 None 1.000 1 2013 2013
CUI: C0040188
Disease: Tic disorder
Tic disorder 		disease Nervous System Diseases; Mental Disorders Mental or Behavioral Dysfunction 33 4 0.010 None 1.000 1 2 2013 2013
CUI: C0033975
Disease: Psychotic Disorders
Psychotic Disorders 		group Mental Disorders Mental or Behavioral Dysfunction 560 179 0.320 None 1.000 3 2 2006 2014
CUI: C0036349
Disease: Paranoid Schizophrenia
Paranoid Schizophrenia 		disease Mental Disorders Mental or Behavioral Dysfunction 53 23 0.330 None 1.000 3 2004 2014
CUI: C0853193
Disease: Bipolar I disorder
Bipolar I disorder 		disease Mental Disorders Mental or Behavioral Dysfunction 83 46 0.020 None 1.000 2 1 2008 2014
CUI: C0815107
Disease: psychological distress
psychological distress 		disease Mental or Behavioral Dysfunction 87 10 0.010 None < 0.001 1 2014 2014
CUI: C0525041
Disease: Neurobehavioral Manifestations
Neurobehavioral Manifestations 		phenotype Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms Sign or Symptom 77 3 0.010 None 1.000 1 2014 2014
CUI: C0085762
Disease: Alcohol abuse
Alcohol abuse 		disease Chemically-Induced Disorders; Mental Disorders Mental or Behavioral Dysfunction 156 24 0.310 None 1.000 1 2 2014 2014
CUI: C0013146
Disease: Drug abuse
Drug abuse 		group Chemically-Induced Disorders; Mental Disorders Mental or Behavioral Dysfunction 405 39 0.010 None 1.000 1 1 2014 2014