APP, amyloid beta precursor protein, 351

N. diseases: 384; N. variants: 105
Source: BEFREE ×
Disease Type Disease Class Semantic Type N. genes d N. SNPs d Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
CUI: C0085220
Disease: Cerebral Amyloid Angiopathy
Cerebral Amyloid Angiopathy 		disease Nutritional and Metabolic Diseases; Nervous System Diseases; Cardiovascular Diseases Disease or Syndrome 60 17 0.500 None 1.000 40 7 1992 2019
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		disease Neoplasms; Skin and Connective Tissue Diseases Neoplastic Process 6500 2145 0.080 None 1.000 8 1 1992 2020
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		disease Neoplasms; Skin and Connective Tissue Diseases Neoplastic Process 6481 2154 0.070 None 1.000 7 1 1992 2020
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		disease Mental Disorders Mental or Behavioral Dysfunction 2217 1332 0.060 None 1.000 6 1 1992 2018
CUI: C0027765
Disease: nervous system disorder
nervous system disorder 		group Nervous System Diseases Disease or Syndrome 942 39 0.050 None 1.000 5 1992 2018
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		disease Mental Disorders Mental or Behavioral Dysfunction 1368 223 0.600 None 0.980 199 11 1993 2020
CUI: C0233794
Disease: Memory impairment
Memory impairment 		phenotype Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms Mental or Behavioral Dysfunction 648 33 0.500 None 0.994 144 3 1993 2020
CUI: C0497327
Disease: Dementia
Dementia 		disease Nervous System Diseases; Mental Disorders Mental or Behavioral Dysfunction 711 165 0.700 strong 0.964 73 10 1993 2020
CUI: C0234985
Disease: Mental deterioration
Mental deterioration 		phenotype Mental Disorders Mental or Behavioral Dysfunction 407 90 0.400 None 0.956 44 4 1993 2020
CUI: C0542476
Disease: Forgetful
Forgetful 		phenotype Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms Sign or Symptom 337 18 0.200 None 1.000 40 1 1993 2020
CUI: C0026848
Disease: Myopathy
Myopathy 		group Musculoskeletal Diseases; Nervous System Diseases Disease or Syndrome 469 93 0.040 None 1.000 4 1 1993 2012
CUI: C0007820
Disease: Cerebrovascular Disorders
Cerebrovascular Disorders 		group Nervous System Diseases; Cardiovascular Diseases Disease or Syndrome 231 56 0.040 None 0.750 4 1993 2019
CUI: C0020179
Disease: Huntington Disease
Huntington Disease 		disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Mental Disorders Disease or Syndrome 945 69 0.030 None 1.000 3 1993 2014
CUI: C0085084
Disease: Motor Neuron Disease
Motor Neuron Disease 		disease Nervous System Diseases Disease or Syndrome 171 35 0.030 None 1.000 3 1993 2011
CUI: C0027066
Disease: Myoclonus
Myoclonus 		phenotype Pathological Conditions, Signs and Symptoms; Nervous System Diseases Sign or Symptom 66 22 0.120 None 1.000 2 2 1993 2016
CUI: C0011268
Disease: Senile dementia
Senile dementia 		disease Nervous System Diseases; Mental Disorders Mental or Behavioral Dysfunction 21 0.010 None 1.000 1 1993 1993
CUI: C0869474
Disease: Dyscalculia
Dyscalculia 		disease Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders Mental or Behavioral Dysfunction 2 0.010 None 1.000 1 1993 1993
CUI: C0011263
Disease: Multi-infarct dementia
Multi-infarct dementia 		disease Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Cardiovascular Diseases Disease or Syndrome 11 0.010 None 1.000 1 1993 1993
CUI: C0206664
Disease: Teratocarcinoma
Teratocarcinoma 		disease Neoplasms Neoplastic Process 139 1 0.010 None 1.000 1 1993 1993
CUI: C0032027
Disease: Pityriasis Rubra Pilaris
Pityriasis Rubra Pilaris 		disease Skin and Connective Tissue Diseases Disease or Syndrome 32 0.010 None 1.000 1 1993 1993
CUI: C1411876
Disease: Developmental arithmetic disorder
Developmental arithmetic disorder 		disease Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders Mental or Behavioral Dysfunction 2 0.010 None 1.000 1 1993 1993
CUI: C0524851
Disease: Neurodegenerative Disorders
Neurodegenerative Disorders 		group Nervous System Diseases Disease or Syndrome 1480 85 0.400 None 0.935 44 1994 2019
CUI: C1842937
Disease: AURAL ATRESIA, CONGENITAL
AURAL ATRESIA, CONGENITAL 		disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities Disease or Syndrome 110 27 0.100 None 0.970 33 3 1995 2019
CUI: C0007682
Disease: CNS disorder
CNS disorder 		group Nervous System Diseases Disease or Syndrome 313 11 0.040 None 1.000 4 1995 2015
CUI: C0520574
Disease: Cerebrovascular amyloidosis
Cerebrovascular amyloidosis 		disease Nutritional and Metabolic Diseases; Nervous System Diseases; Cardiovascular Diseases Disease or Syndrome 4 0.030 None 1.000 3 1995 1999