Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0030567
Disease: Parkinson Disease
Parkinson Disease 		0.400 GeneticVariation disease BEFREE We replicated the effect of a new locus detected in the Japanese cohort (PARK16, rs823128, OR = 0.66, P = 7.29 x 10(-8)) and provide supporting evidence that common variation around LRRK2 modulates risk for PD (rs1491923, OR = 1.14, P = 1.55 x 10(-5)). 19915575 2009
CUI: C0030567
Disease: Parkinson Disease
Parkinson Disease 		0.400 Biomarker disease CTD_human By comparing results of a GWAS performed on individuals of European ancestry, we identified PARK16, SNCA and LRRK2 as shared risk loci for PD and BST1 and MAPT as loci showing population differences. 19915576 2009
CUI: C0030567
Disease: Parkinson Disease
Parkinson Disease 		0.400 Biomarker disease CTD_human We replicated the effect of a new locus detected in the Japanese cohort (PARK16, rs823128, OR = 0.66, P = 7.29 x 10(-8)) and provide supporting evidence that common variation around LRRK2 modulates risk for PD (rs1491923, OR = 1.14, P = 1.55 x 10(-5)). 19915575 2009
CUI: C0030567
Disease: Parkinson Disease
Parkinson Disease 		0.400 GeneticVariation disease BEFREE By comparing results of a GWAS performed on individuals of European ancestry, we identified PARK16, SNCA and LRRK2 as shared risk loci for PD and BST1 and MAPT as loci showing population differences. 19915576 2009
CUI: C4511452
Disease: Sporadic Parkinson disease
Sporadic Parkinson disease 		0.030 GeneticVariation disease BEFREE Many genetic variants have been linked to familial or sporadic Parkinson's disease (PD), among which those identified in PARK16, BST1, SNCA, LRRK2, GBA and MAPT genes have been demonstrated to be the most common risk factors worldwide. 27299523 2016
CUI: C4511452
Disease: Sporadic Parkinson disease
Sporadic Parkinson disease 		0.030 GeneticVariation disease BEFREE PARK16 polymorphisms, interaction with smoking, and sporadic Parkinson's disease in Japan. 26944116 2016
CUI: C4511452
Disease: Sporadic Parkinson disease
Sporadic Parkinson disease 		0.030 GeneticVariation disease BEFREE We also validated 2 new single-nucleotide polymorphisms, rs947211 and rs823144, in PARK16 to explore their association with susceptibility to PD in the Xinjiang Uygur and Han populations. 25966061 2015
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.010 Biomarker disease BEFREE Our results confirm the associations of SNCA, LRRK2, BST1, and PARK16 with PD susceptibility and fail to show significant associations of AD genome-wide association study (GWAS) top hits with PD susceptibility in a Korean population. 23820587 2013
CUI: C0026650
Disease: Movement Disorders
Movement Disorders 		0.010 GeneticVariation group BEFREE Our findings suggest that additional studies of PARK16-18 are necessary to establish the role of these loci in modifying risk for Parkinson's disease in European-derived populations.© 2011 Movement Disorder Society. 21425343 2011
CUI: C3160718
Disease: PARKINSON DISEASE, LATE-ONSET
PARKINSON DISEASE, LATE-ONSET 		0.010 GeneticVariation disease BEFREE We performed direct DNA sequencing of the RAB7L1 and SLC41A1 genes within the PARK16 locus in 205 Chinese Parkinson's disease (PD) patients. 21812739 2011