|
Malignant neoplasm of lung
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The methylation status of 6 genes, including a candidate tumor suppressor gene (BLU), the cadherin 13 gene (CDH13), the fragile histidine triad gene (FHIT), the cell cycle control gene p16, the retinoic acid receptor beta gene (RARbeta), and the Ras association domain family 1 gene (RASSF1A), was examined in plasma samples, corresponding tumor tissues, and normal lung tissues from a group of 63 patients with lung cancer and in plasma samples from 36 cancer-free individuals.
|
17876837 |
2007 |
|
Substance Use Disorders
|
0.330 |
GeneticVariation
|
group |
BEFREE |
A total of 110 adult patients with ASD (n=61) or ADHD (n=49) with or without a lifetime history of SUD participated in a study in which we genotyped polymorphisms in five known candidate genes for (one of) the disorders, i.e. the 5HTTLPR in SLC6A4/5-HTT, rs1800497 (TaqIA C>T) in DRD2, rs7794745 in CNTNAP2, rs1843809 in TPH2, and rs6565113 in CDH13.
|
20446882 |
2010 |
|
Substance Use Disorders
|
0.330 |
GeneticVariation
|
group |
BEFREE |
Genome-wide association studies in humans have suggested that variants of the cadherin-13 (CDH13) gene are associated with substance use disorder, subjective response to amphetamine, and attention deficit hyperactivity disorder.
|
28387990 |
2017 |
|
Alcoholic Intoxication, Chronic
|
0.320 |
GeneticVariation
|
disease |
BEFREE |
Nine SNPs were located in genes, including the CDH13 and ADH1C genes, that have been reported to be associated with alcohol dependence.
|
19581569 |
2009 |
|
Alzheimer's Disease
|
0.110 |
GeneticVariation
|
disease |
GWASCAT |
Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
|
26830138 |
2016 |
|
Crohn Disease
|
0.110 |
GeneticVariation
|
disease |
GWASCAT |
Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease.
|
28067908 |
2017 |
|
Chronic Obstructive Airway Disease
|
0.110 |
GeneticVariation
|
disease |
BEFREE |
The aim of this study was to investigate the effects of CDH13 variants on COPD susceptibility in a Chinese population.
|
26806298 |
2016 |
|
Chronic Obstructive Airway Disease
|
0.110 |
GeneticVariation
|
disease |
GWASCAT |
A genome-wide analysis of the response to inhaled β2-agonists in chronic obstructive pulmonary disease.
|
26503814 |
2016 |
|
Coronary Artery Disease
|
0.110 |
GeneticVariation
|
disease |
GWASCAT |
Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.
|
29212778 |
2018 |
|
Coronary Artery Disease
|
0.110 |
GeneticVariation
|
disease |
BEFREE |
Resequencing and EpiTYPER™ assay were applied for the HYPertension in ESTonia/Coronary Artery Disease in Czech (HYPEST/CADCZ; n = 358) samples to identify CDH13 promoter SNPs acting as methylation Quantitative Trait Loci (meQTLs) and to investigate their associations with CMT.
|
25543204 |
2015 |
|
Coronary Artery Disease
|
0.110 |
GeneticVariation
|
disease |
GWASCAT |
Efficiently controlling for case-control imbalance and sample relatedness in large-scale genetic association studies.
|
30104761 |
2018 |
|
Coronary Artery Disease
|
0.110 |
GeneticVariation
|
disease |
GWASCAT |
Association analyses based on false discovery rate implicate new loci for coronary artery disease.
|
28714975 |
2017 |
|
Coronary Artery Disease
|
0.110 |
GeneticVariation
|
disease |
GWASCAT |
Genetic analysis in UK Biobank links insulin resistance and transendothelial migration pathways to coronary artery disease.
|
28714974 |
2017 |
|
Blood Pressure
|
0.100 |
GeneticVariation
|
phenotype |
GWASDB |
Framingham Heart Study 100K Project: genome-wide associations for blood pressure and arterial stiffness.
|
17903302 |
2007 |
|
Malignant Neoplasms
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Abnormalities in the H-cadherin gene have been reported in several human malignancies, including nonsmall cell lung carcinoma (NSCLC).
|
16177988 |
2005 |
|
Hypothyroidism
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Detection and interpretation of shared genetic influences on 42 human traits.
|
27182965 |
2016 |
|
Leukemia, Myelocytic, Acute
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.
|
27903959 |
2017 |
|
Malaria
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Imputation-based meta-analysis of severe malaria in three African populations.
|
23717212 |
2013 |
|
Malaria
|
0.100 |
GeneticVariation
|
disease |
GWASDB |
Imputation-based meta-analysis of severe malaria in three African populations.
|
23717212 |
2013 |
|
Neoplasms
|
0.100 |
GeneticVariation
|
group |
BEFREE |
WIF-1 and CDH13 promoter methylations were associated with the degree of tumor differentiation and WIF-1 and RASSF1A promoter methylations were associated with age (all P<0.05).
|
27506957 |
2016 |
|
Neoplasms
|
0.100 |
GeneticVariation
|
group |
BEFREE |
The methylation status of 6 genes, including a candidate tumor suppressor gene (BLU), the cadherin 13 gene (CDH13), the fragile histidine triad gene (FHIT), the cell cycle control gene p16, the retinoic acid receptor beta gene (RARbeta), and the Ras association domain family 1 gene (RASSF1A), was examined in plasma samples, corresponding tumor tissues, and normal lung tissues from a group of 63 patients with lung cancer and in plasma samples from 36 cancer-free individuals.
|
17876837 |
2007 |
|
Neoplasms
|
0.100 |
GeneticVariation
|
group |
BEFREE |
While the following sixteen genes remained the unmethylated in all tumor and normal tissues: CDH1, APAF1, hMLH1, BRCA1, hTERC, VHL, RARbeta, TIMP3, DAPK1, SURVIVIN, p14ARF, RB1, p15INK4b, APC, RASSF1c and PTEN, varying degrees of tumor specific hypermethylation were associated with the p16INK4a, RASSF1a, CASP8 and CDH13 genes.
|
12433278 |
2002 |
|
Neoplasms
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Tumor size was associated with RIL and CDH13 methylation (both p = 0.002), and S-phase was associated with RIL methylation (p = 0.036).
|
22695491 |
2012 |
|
Schizophrenia
|
0.100 |
GeneticVariation
|
disease |
GWASDB |
Genome-wide study of association and interaction with maternal cytomegalovirus infection suggests new schizophrenia loci.
|
23358160 |
2014 |
|
Schizophrenia
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Genome-wide study of association and interaction with maternal cytomegalovirus infection suggests new schizophrenia loci.
|
23358160 |
2014 |