CHRM4, cholinergic receptor muscarinic 4, 1132

N. diseases: 33; N. variants: 2
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0040822
Disease: Tremor
Tremor 		0.300 Biomarker phenotype CTD_human Characterization of the muscarinic receptor subtype mediating pilocarpine-induced tremulous jaw movements in rats. 9920179 1999
CUI: C0040827
Disease: Saturnine Tremor
Saturnine Tremor 		0.300 Biomarker phenotype CTD_human Characterization of the muscarinic receptor subtype mediating pilocarpine-induced tremulous jaw movements in rats. 9920179 1999
CUI: C0149840
Disease: Senile Tremor
Senile Tremor 		0.300 Biomarker phenotype CTD_human Characterization of the muscarinic receptor subtype mediating pilocarpine-induced tremulous jaw movements in rats. 9920179 1999
CUI: C0234370
Disease: Persistent Tremor
Persistent Tremor 		0.300 Biomarker phenotype CTD_human Characterization of the muscarinic receptor subtype mediating pilocarpine-induced tremulous jaw movements in rats. 9920179 1999
CUI: C0234371
Disease: Continuous Tremor
Continuous Tremor 		0.300 Biomarker phenotype CTD_human Characterization of the muscarinic receptor subtype mediating pilocarpine-induced tremulous jaw movements in rats. 9920179 1999
CUI: C0234372
Disease: Intermittent Tremor
Intermittent Tremor 		0.300 Biomarker phenotype CTD_human Characterization of the muscarinic receptor subtype mediating pilocarpine-induced tremulous jaw movements in rats. 9920179 1999
CUI: C0234373
Disease: Fine Tremor
Fine Tremor 		0.300 Biomarker phenotype CTD_human Characterization of the muscarinic receptor subtype mediating pilocarpine-induced tremulous jaw movements in rats. 9920179 1999
CUI: C0234374
Disease: Coarse Tremor
Coarse Tremor 		0.300 Biomarker phenotype CTD_human Characterization of the muscarinic receptor subtype mediating pilocarpine-induced tremulous jaw movements in rats. 9920179 1999
CUI: C0234375
Disease: Massive Tremor
Massive Tremor 		0.300 Biomarker phenotype CTD_human Characterization of the muscarinic receptor subtype mediating pilocarpine-induced tremulous jaw movements in rats. 9920179 1999
CUI: C0234376
Disease: Action Tremor
Action Tremor 		0.300 Biomarker phenotype CTD_human Characterization of the muscarinic receptor subtype mediating pilocarpine-induced tremulous jaw movements in rats. 9920179 1999
CUI: C0234377
Disease: Passive Tremor
Passive Tremor 		0.300 Biomarker phenotype CTD_human Characterization of the muscarinic receptor subtype mediating pilocarpine-induced tremulous jaw movements in rats. 9920179 1999
CUI: C0234378
Disease: Static Tremor
Static Tremor 		0.300 Biomarker phenotype CTD_human Characterization of the muscarinic receptor subtype mediating pilocarpine-induced tremulous jaw movements in rats. 9920179 1999
CUI: C0234379
Disease: Resting Tremor
Resting Tremor 		0.300 Biomarker phenotype CTD_human Characterization of the muscarinic receptor subtype mediating pilocarpine-induced tremulous jaw movements in rats. 9920179 1999
CUI: C0234381
Disease: Darkness Tremor
Darkness Tremor 		0.300 Biomarker phenotype CTD_human Characterization of the muscarinic receptor subtype mediating pilocarpine-induced tremulous jaw movements in rats. 9920179 1999
CUI: C0235078
Disease: Tremor, Perioral
Tremor, Perioral 		0.300 Biomarker phenotype CTD_human Characterization of the muscarinic receptor subtype mediating pilocarpine-induced tremulous jaw movements in rats. 9920179 1999
CUI: C0235081
Disease: Tremor, Limb
Tremor, Limb 		0.300 Biomarker phenotype CTD_human Characterization of the muscarinic receptor subtype mediating pilocarpine-induced tremulous jaw movements in rats. 9920179 1999
CUI: C0235082
Disease: Tremor, Muscle
Tremor, Muscle 		0.300 Biomarker phenotype CTD_human Characterization of the muscarinic receptor subtype mediating pilocarpine-induced tremulous jaw movements in rats. 9920179 1999
CUI: C0235083
Disease: Nerve Tremors
Nerve Tremors 		0.300 Biomarker phenotype CTD_human Characterization of the muscarinic receptor subtype mediating pilocarpine-induced tremulous jaw movements in rats. 9920179 1999
CUI: C0235843
Disease: Tremor, Neonatal
Tremor, Neonatal 		0.300 Biomarker phenotype CTD_human Characterization of the muscarinic receptor subtype mediating pilocarpine-induced tremulous jaw movements in rats. 9920179 1999
CUI: C0751564
Disease: Pill Rolling Tremor
Pill Rolling Tremor 		0.300 Biomarker phenotype CTD_human Characterization of the muscarinic receptor subtype mediating pilocarpine-induced tremulous jaw movements in rats. 9920179 1999
CUI: C0751565
Disease: Tremor, Semirhythmic
Tremor, Semirhythmic 		0.300 Biomarker phenotype CTD_human Characterization of the muscarinic receptor subtype mediating pilocarpine-induced tremulous jaw movements in rats. 9920179 1999
CUI: C1527384
Disease: Involuntary Quiver
Involuntary Quiver 		0.300 Biomarker phenotype CTD_human Characterization of the muscarinic receptor subtype mediating pilocarpine-induced tremulous jaw movements in rats. 9920179 1999
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.360 AlteredExpression disease LHGDN To test the hypothesis that muscarinic receptors are involved in the pathology of schizophrenia, we measured muscarinic(1) (M1R) and muscarinic(4)(M4R) protein and mRNA as well as [(3)H]pirenzepine binding in Brodmann's areas (BA) 9 and 40 obtained postmortem from 20 schizophrenic and 20 age/sex-matched control subjects. 12476323 2002
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.360 Biomarker disease BEFREE To test the hypothesis that muscarinic receptors are involved in the pathology of schizophrenia, we measured muscarinic(1) (M1R) and muscarinic(4)(M4R) protein and mRNA as well as [(3)H]pirenzepine binding in Brodmann's areas (BA) 9 and 40 obtained postmortem from 20 schizophrenic and 20 age/sex-matched control subjects. 12476323 2002
CUI: C0007398
Disease: Catatonia
Catatonia 		0.300 Therapeutic disease CTD_human Effect of M4-cholinoceptor blockade on haloperidol-produced catatonic syndrome in rats. 15273762 2004