|
Mental Depression
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Controlling for inflammatory activity at BD1, depression at BD1, demographics and the time between assessments, increases in interleukin-6 (IL-6; b = 0.878, p = .007) and C-reactive protein (CRP; b = 0.252, p = .024) from BD1 to BD2 interacted with recent stressful life events before BD1 to predict severity of depressive symptoms at BD2.
|
30822466 |
2019 |
|
Mental Depression
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Decreased UA levels showed weak negative correlation with the presence of sadness and disturbed daily activities, higher CRP levels positively correlated with severe depression and the correlation between depression and fatigue was also observed (p < 0.05).
|
30182258 |
2018 |
|
Mental Depression
|
0.100 |
Biomarker
|
disease |
BEFREE |
A longitudinal cohort study was performed with repeated measures of pain (0-10 numeric rating scale) and evaluation of other self-reported symptoms (Hospital Anxiety and Depression Scale, Pittsburgh Sleep Quality Index, and Fatigue Severity Score), daily functioning (Lawton Instrumental Activities of Daily Living Scale), quality of life (EQ-5D-3L), knee function (KSS Knee and Function Score), perioperative and clinical characteristics (e.g. surgery duration, brand of implant, comorbidities), biochemical parameters (haemoglobin, C-reactive protein, creatinine), and patient satisfaction (20-item scale).
|
28916991 |
2018 |
|
Mental Depression
|
0.100 |
Biomarker
|
disease |
BEFREE |
There was no difference in TNF-α (p = 0.351) and CRP (p = 0.05) between those with depression and controls.
|
30104698 |
2018 |
|
Mental Depression
|
0.100 |
Biomarker
|
disease |
BEFREE |
Conclusions The level of CRP plays a role of biomarker to differentiate between MDD and BD II depression in both their depressed and euthymic state.
|
26895280 |
2017 |
|
Mental Depression
|
0.100 |
Biomarker
|
disease |
BEFREE |
The depression sum-score was related to both IL-6 and CRP before, and only to IL-6 after covariate adjustment.
|
31615595 |
2019 |
|
Mental Depression
|
0.100 |
Biomarker
|
disease |
BEFREE |
The present study examines associations between peripheral CRP concentrations and threat-related amygdala activity, a neural biomarker of depression and anxiety risk, in a sample of 172 young adult undergraduate students.
|
28183031 |
2017 |
|
Mental Depression
|
0.100 |
Biomarker
|
disease |
BEFREE |
A total of 126 patients with PsA were included and the following variables were assessed: Tender joint count (TJC), swollen joint count (SJC), patient's global assessment, physician's global assessment, pain, extra-articular manifestations, Psoriasis Area and Severity Index, Health Assessment Questionnaire, fatigue, Short Form-36, psoriatic quality of life, Hospital Anxiety and Depression Scale and C-reactive protein (CRP).
|
30426235 |
2019 |
|
Mental Depression
|
0.100 |
Biomarker
|
disease |
BEFREE |
The odds of depression increased by 2% (95% CI = 1-4%) for every unit (mg/l) increase of CRP and nearly doubled for men with CRP > or = 3 mg/l vs <1 mg/l [odds ratio (OR) = 1.95, 95% confidence interval (CI) = 1.27-2.98].
|
19433520 |
2009 |
|
Mental Depression
|
0.100 |
Biomarker
|
disease |
BEFREE |
This indicates that CRP per se is not a causal risk factor for depression.
|
24246360 |
2014 |
|
Mental Depression
|
0.100 |
Biomarker
|
disease |
BEFREE |
Role of IL-8, CRP and epidermal growth factor in depression and anxiety patients treated with mindfulness-based therapy or cognitive behavioral therapy in primary health care.
|
28501736 |
2017 |
|
Mental Depression
|
0.100 |
Biomarker
|
disease |
BEFREE |
A complete clinical assessment, assessment of vascular risk factors, blood sample for the evaluation of serum CRP was obtained, and baseline depression severity was measured on Hamilton Depression Rating Scale (HDRS).
|
30581212 |
2020 |
|
Mental Depression
|
0.100 |
Biomarker
|
disease |
BEFREE |
When stratifying by zygosity, significant associations from IL-6 to depression were only seen in monozygotic twins, but associations from depression to CRP were more robust in dizygotic twins, which implies that genetic factors may play a role in this association.
|
30394311 |
2019 |
|
Mental Depression
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Logistic regression analyses revealed that menstrual status, chronic diseases, serum inflammatory factors (CRP, IL-6 and TNF-α) and BDNF levels had independent predictive values for depression in patients with perimenopausal syndrome (P<0.05).
|
29849779 |
2018 |
|
Mental Depression
|
0.100 |
Biomarker
|
disease |
BEFREE |
The effect between depression and CRP was small, but highly significant across all stages of the meta-analysis (p < 0.01).
|
29928963 |
2018 |
|
Mental Depression
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
CRP SNPs rs1800947 and rs2794521 may be associated with depressive symptoms in patients with depression in a sexspecific fashion.
|
31711279 |
2019 |
|
Mental Depression
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
We have examined whether longitudinal patterns of inflammation, based on three CRP measurements from childhood to early-adulthood, are associated with the risk of depression in early-adulthood in the Avon Longitudinal Study of Parents and Children, a prospective birth cohort.
|
31707310 |
2020 |
|
Mental Depression
|
0.100 |
Biomarker
|
disease |
BEFREE |
This study explored the relation between baseline anxiety as measured by the Beck Anxiety Inventory and depression as measured by the Beck Depression Inventory-II and baseline serum c-reactive protein (CRP) in a cross-sectional sample of 100 participants [mean (SD) age 57.8 (7.7) years; 64% female] with obesity [mean (SD) body mass index, BMI 37.3 (5.5) kg/m<sup>2</sup> ] enrolled in a clinical trial for pharmacological weight loss.
|
28000423 |
2017 |
|
Mental Depression
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Depression and anxiety both associate with serum level of hs-CRP: A gender-stratified analysis in a population-based study.
|
28419913 |
2017 |
|
Mental Depression
|
0.100 |
Biomarker
|
disease |
BEFREE |
Separate generalised estimating equation models estimated standardised associations between CRP and (i) baseline functional status and (ii) change in function over time, adjusting for demographics, vascular risk factors, social variables, cognition, and depression measured at baseline, and stroke and MI occurring during follow-up.
|
28181636 |
2017 |
|
Mental Depression
|
0.100 |
Biomarker
|
disease |
BEFREE |
Lower Serum Zinc and Higher CRP Strongly Predict Prenatal Depression and Physio-somatic Symptoms, Which All Together Predict Postnatal Depressive Symptoms.
|
26846364 |
2017 |
|
Mental Depression
|
0.100 |
Biomarker
|
disease |
BEFREE |
In women, there was no association between CRP and telomere length, regardless of the depression status.
|
31109116 |
2019 |
|
Mental Depression
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
In four longitudinal studies, high levels of CRP were found to be associated with depression even after adjustment for BMI and weight loss, further corroborating the idea that other sources of peripheral inflammation might contribute to depressive symptoms.
|
29550676 |
2018 |
|
Mental Depression
|
0.100 |
Biomarker
|
disease |
BEFREE |
After additionally controlling for physical activity, elevated WBC count (p = 0.002) and decreased levels of urine cortisol (p = 0.05) remained significant predictors of PTSD course, and elevated WBC count (p = 0.001), CRP (p = 0.03), and fibrinogen (p = 0.02) remained significant predictors of depression course.
|
30389462 |
2019 |
|
Mental Depression
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
IL-6 and CRP levels were elevated among those with lifetime depression and, among those with depression only, IL-6 methylation showed an inverse correlation with circulating IL-6 and CRP.
|
20836906 |
2011 |