|
Cerebrovascular accident
|
0.100 |
Biomarker
|
group |
BEFREE |
Elevated CRP may have a role in increasing stroke risk.
|
29466947 |
2018 |
|
Cerebrovascular accident
|
0.100 |
Biomarker
|
group |
BEFREE |
In a recent US-based nationwide registry study, about 10% of all hospitalized ischemic stroke patients had comorbid cancer, with a slight rise in this rate over the last decade.<sup>2</sup> Stroke patients diagnosed with occult cancer are usually older with men being at a higher risk of having comorbid cancer.<sup>3,4</sup> In addition, probability of cancer diagnosis after stroke is associated with smoking, elevated D-dimer, elevated C-reactive protein (CRP), and anemia on admission.
|
31701522 |
2020 |
|
Cerebrovascular accident
|
0.100 |
Biomarker
|
group |
BEFREE |
ROC curve analysis shows the area under curve of the statistical model was 0.823, the analysis of diagnostic threshold for prognostic factors indicated that age, diffusion-weighted imaging lesion volume, glucose on admission, National Institutes of Health Stroke Scale score on admission and hypersensitive C-reactive protein were valuable predictive factors for the outcome of EVT (P<0.05).
|
31641377 |
2019 |
|
Cerebrovascular accident
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Although these variants and corresponding haplotypes in the CRP gene are associated with serum CRP concentrations, our study does not support that variants and corresponding haplotypes studied here have a major influence on risk of stroke and stroke recurrence.
|
20184533 |
2010 |
|
Cerebrovascular accident
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Serum levels of CRP and ICAS severity were assessed at admission and cognitive status was assessed 6 months after stroke using the Six-Item Screener.
|
29451096 |
2018 |
|
Cerebrovascular accident
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Body mass index (BMI), waist circumference values, the average values of systolic (SBP) and diastolic (DBP) blood pressures and heart rate, total serum cholesterol levels, serum HDL (high-density lipoprotein) cholesterol levels, serum LDL (low-density lipoprotein) cholesterol levels, serum triglycerides levels, serum lipoprotein A levels, serum CRP (C-reactive protein) levels, plasma homocysteine levels, serum uric acid levels, individual and relative risks of having a heart attack or stroke over the next ten years were compared between groups (50 GH, 102 PE, 34 FGR and 90 normal pregnancies) and correlated with the severity of the disease with regard to clinical signs (25 PE without severe features, 77 PE with severe features), and delivery date (36 early PE, 66 late PE).
|
31010048 |
2019 |
|
Cerebrovascular accident
|
0.100 |
Biomarker
|
group |
BEFREE |
Multiple logistic regression was applied to evaluate the association of CRP gene and stroke hsCRP elevation with adjustment for covariates.
|
22875596 |
2013 |
|
Cerebrovascular accident
|
0.100 |
Biomarker
|
group |
BEFREE |
In participant data from the Wandsworth Heart and Stroke Study including European, South Asian and African, and Caribbean-descent subjects, body mass index, systolic blood pressure, and smoking contributed to between-group differences in CRP, but the majority of the difference in CRP was unexplained.
|
20876875 |
2010 |
|
Cerebrovascular accident
|
0.100 |
Biomarker
|
group |
BEFREE |
Therefore, CRP can be a good target for drug discovery to prevent disease pathogenesis, especially cardioprotection in acute myocardial infarction and neuroprotection in stroke.
|
21541851 |
2011 |
|
Cerebrovascular accident
|
0.100 |
Biomarker
|
group |
BEFREE |
We sought to investigate whether CRP measured before tissue plasminogen activator (tPA) treatments may add prognostic information to guide stroke thrombolysis.
|
16601211 |
2006 |
|
Cerebrovascular accident
|
0.100 |
Biomarker
|
group |
BEFREE |
Furthermore, we found that ESR and LDL-C levels could exhibit a linear association with the risk of comorbid stroke while CRP level had a nonlinearity association with stroke risk among RA patients.
|
30729371 |
2019 |
|
Cerebrovascular accident
|
0.100 |
AlteredExpression
|
group |
BEFREE |
However, serum folate and vitamin B<sub>12</sub> levels were not associated with the risk of stroke, coronary artery disease, or myocardial infarction or the development of peripheral arterial disease after adjustment for age, sex, smoking status, alcohol consumption, physical activity, body mass index, serum creatinine, and high-sensitivity C-reactive protein levels and a history of diabetes, hypertension, or dyslipidemia.
|
30824395 |
2019 |
|
Cerebrovascular accident
|
0.100 |
GeneticVariation
|
group |
BEFREE |
In both sexes, there was no difference between patients with normal or high CRP regarding overall macroangiopathy (42% vs. 45% [men]; 27% vs. 28% [women]), coronary and peripheral artery disease, or stroke.
|
31477553 |
2019 |
|
Cerebrovascular accident
|
0.100 |
Biomarker
|
group |
BEFREE |
The parameters leukocyte and thrombocyte count, C-reactive protein, fibrinogen, D-dimer, activated partial thromboplastin time (aPTT) and prothrombin time were extracted from hospital-based medical records of patients (n = 60) with sCAD and compared with those of a control group (n = 97) from a prospective observational stroke study.
|
29224120 |
2018 |
|
Cerebrovascular accident
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Onset of vascular events and each stroke subtype in relation to Hs-CRP levels were also determined.
|
28302952 |
2017 |
|
Cerebrovascular accident
|
0.100 |
GeneticVariation
|
group |
BEFREE |
A secondary aim was to study the relationship between the 1444C>T polymorphism, plasma levels of CRP and stroke.
|
19390179 |
2009 |
|
Cerebrovascular accident
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Neither CRP genotypes nor haplotypes showed an association with hemorrhagic stroke.
|
19262552 |
2009 |
|
Cerebrovascular accident
|
0.100 |
Biomarker
|
group |
BEFREE |
Patients with BAD have higher initial National Institutes of Health Stroke Scale scores and incidence of progressive motor deficits compared with those with LD; CRP is associated with the progression in both groups.
|
27050473 |
2017 |
|
Cerebrovascular accident
|
0.100 |
Biomarker
|
group |
BEFREE |
In the recently completed JUPITER trial, men and women without prior cardiovascular disease or diabetes who had baseline low-density lipoprotein cholesterol <130 mg/dL and high-sensitivity C-reactive protein ≥ 2 mg/L were randomly allocated to rosuvastatin 20 mg daily or to placebo and followed for first major vascular events (nonfatal myocardial infarction, nonfatal stroke, hospitalization for unstable angina, arterial revascularization, or vascular death) and for all-cause mortality.
|
21493817 |
2011 |
|
Cerebrovascular accident
|
0.100 |
Biomarker
|
group |
BEFREE |
Higher D-dimer increased the risk of stroke and CHD independent of cardiovascular risk factors and CRP, with perhaps a stronger association for CHD versus stroke in blacks than whites.
|
28004063 |
2017 |
|
Cerebrovascular accident
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Standardized CRP levels were higher in patients with post-stroke infections beyond 24 h. Standardized CRP levels in the fourth quartile were independently associated with infection in two different logistic regression models, model 1 [stroke severity and dysphagia, odds ratio = 9.70 (3.10-30.41)] and model 2 [age, sex, and stroke severity, odds ratio = 3.21 (1.93-5.32)].
|
28171699 |
2017 |
|
Cerebrovascular accident
|
0.100 |
Biomarker
|
group |
BEFREE |
Ten-year standardization of lipids and high-sensitivity C-reactive protein in a randomized controlled trial to assess the effects of statins on secondary stroke prevention: Japan Statin Treatment Against Recurrent Stroke.
|
28135841 |
2018 |
|
Cerebrovascular accident
|
0.100 |
Biomarker
|
group |
BEFREE |
At the end of the 5-year follow- up, compared with subjects without MS, hazard ratios and 95% confidence intervals for the different risks in subjects with MS were 1.86 (1.02-3.29) for myocardial infarction (MI), 1.39 (1.01-2.05) for stroke, 1.52 (1.02- 2.37) for CVD death, and 1.13 (0.62-2.58) for total death, after adjusting for age, gender, smoking, drinking, physical activity, uric acid, high-sensitivity C-reactive protein, dietary factors and carotid atherosclerosis status.
|
31826385 |
2019 |
|
Cerebrovascular accident
|
0.100 |
Biomarker
|
group |
BEFREE |
However, elevated CRP and Hcy levels were associated with a non-significant trend in hemorrhage size and mortality suggesting that CRP and Hcy-lowering therapies may decrease hemorrhagic stroke risk and severity.
|
30613458 |
2018 |
|
Cerebrovascular accident
|
0.100 |
AlteredExpression
|
group |
BEFREE |
The role of very high high-sensitivity C-reactive protein levels on mortality after stroke.
|
28017191 |
2017 |