PARP1, poly(ADP-ribose) polymerase 1, 142

N. diseases: 565; N. variants: 23
Disease: Malignant transformation ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1608408
Disease: Malignant transformation
Malignant transformation 		0.030 Biomarker phenotype BEFREE PARP-1 regulates metastatic melanoma through modulation of vimentin-induced malignant transformation. 23785295 2013
CUI: C1608408
Disease: Malignant transformation
Malignant transformation 		0.030 AlteredExpression phenotype BEFREE We propose that exposure to asbestos inhibits the PARP1 activity possibly resulting in higher DNA instability, thus causing malignant transformation. 21543585 2011
CUI: C1608408
Disease: Malignant transformation
Malignant transformation 		0.030 AlteredExpression phenotype BEFREE Epigenetic mediated transcriptional activation of PARP-1 participates in silica-associated malignant transformation of human bronchial epithelial cells. 20123007 2010