Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0018803
Disease: Heart Function Tests
Heart Function Tests
0.100 GeneticVariation phenotype GWASDB Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction. 21076409 2010
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.420 Biomarker disease CTD_human We found a colorectal carcinoma cell line harboring the fusion gene to be dependent on VTI1A-TCF7L2 for anchorage-independent growth using RNA interference-mediated knockdown. 21892161 2011
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.400 Biomarker group CTD_human Genomic sequencing of colorectal adenocarcinomas identifies a recurrent VTI1A-TCF7L2 fusion. 21892161 2011
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
0.300 Biomarker group CTD_human Genomic sequencing of colorectal adenocarcinomas identifies a recurrent VTI1A-TCF7L2 fusion. 21892161 2011
CUI: C0205641
Disease: Adenocarcinoma, Basal Cell
Adenocarcinoma, Basal Cell
0.300 Biomarker disease CTD_human Genomic sequencing of colorectal adenocarcinomas identifies a recurrent VTI1A-TCF7L2 fusion. 21892161 2011
CUI: C0205642
Disease: Adenocarcinoma, Oxyphilic
Adenocarcinoma, Oxyphilic
0.300 Biomarker disease CTD_human Genomic sequencing of colorectal adenocarcinomas identifies a recurrent VTI1A-TCF7L2 fusion. 21892161 2011
CUI: C0205643
Disease: Carcinoma, Cribriform
Carcinoma, Cribriform
0.300 Biomarker disease CTD_human Genomic sequencing of colorectal adenocarcinomas identifies a recurrent VTI1A-TCF7L2 fusion. 21892161 2011
CUI: C0205644
Disease: Carcinoma, Granular Cell
Carcinoma, Granular Cell
0.300 Biomarker disease CTD_human Genomic sequencing of colorectal adenocarcinomas identifies a recurrent VTI1A-TCF7L2 fusion. 21892161 2011
CUI: C0205645
Disease: Adenocarcinoma, Tubular
Adenocarcinoma, Tubular
0.300 Biomarker disease CTD_human Genomic sequencing of colorectal adenocarcinomas identifies a recurrent VTI1A-TCF7L2 fusion. 21892161 2011
CUI: C0019196
Disease: Hepatitis C
Hepatitis C
0.010 Biomarker disease BEFREE Follow-up assays with in vitro HCV cell culture systems validated VTI1A, a vesicular transport associated factor, which was upregulated in CoreTG but not in PA28γ(-/-)CoreTG, as a novel regulator of HCV release but not replication. 22646850 2012
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.110 GeneticVariation disease GWASDB Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia. 23143601 2012
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
0.110 GeneticVariation disease GWASCAT Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia. 23143601 2012
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.420 GeneticVariation disease BEFREE In conclusion, we have identified novel variants of VTI1A-TCF7L2 fusion transcripts, including a novel fusion partner gene, RP11-57H14.3, and demonstrated detectable levels in a large fraction of CRC samples, as well as in normal colonic mucosa and other tissue types. 24608966 2014
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.420 GeneticVariation disease GWASCAT Trans-ethnic genome-wide association study of colorectal cancer identifies a new susceptibility locus in VTI1A. 25105248 2014
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.420 GeneticVariation disease BEFREE This study reveals a new pan-ethnic CRC risk locus at 10q25 (rs12241008, intronic to VTI1A; P=1.4 × 10(-9)), providing additional insight into the aetiology of CRC and highlighting the value of association mapping in diverse populations. 25105248 2014
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.400 GeneticVariation group GWASCAT Trans-ethnic genome-wide association study of colorectal cancer identifies a new susceptibility locus in VTI1A. 25105248 2014
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.110 GeneticVariation disease GWASCAT Trans-ethnic genome-wide association study of colorectal cancer identifies a new susceptibility locus in VTI1A. 25105248 2014
Malignant neoplasm of large intestine
0.100 GeneticVariation disease GWASCAT Trans-ethnic genome-wide association study of colorectal cancer identifies a new susceptibility locus in VTI1A. 25105248 2014
CUI: C1319315
Disease: Adenocarcinoma of large intestine
Adenocarcinoma of large intestine
0.100 GeneticVariation disease GWASCAT Trans-ethnic genome-wide association study of colorectal cancer identifies a new susceptibility locus in VTI1A. 25105248 2014
COLORECTAL CANCER, SUSCEPTIBILITY TO, 1
0.100 GeneticVariation disease GWASCAT Trans-ethnic genome-wide association study of colorectal cancer identifies a new susceptibility locus in VTI1A. 25105248 2014
COLORECTAL CANCER, SUSCEPTIBILITY TO, 10
0.100 GeneticVariation disease GWASCAT Trans-ethnic genome-wide association study of colorectal cancer identifies a new susceptibility locus in VTI1A. 25105248 2014
COLORECTAL CANCER, SUSCEPTIBILITY TO, 3
0.100 GeneticVariation phenotype GWASCAT Trans-ethnic genome-wide association study of colorectal cancer identifies a new susceptibility locus in VTI1A. 25105248 2014
COLORECTAL CANCER, SUSCEPTIBILITY TO, 12
0.100 GeneticVariation disease GWASCAT Trans-ethnic genome-wide association study of colorectal cancer identifies a new susceptibility locus in VTI1A. 25105248 2014
Malignant neoplasm of colon and/or rectum
0.010 GeneticVariation disease BEFREE Trans-ethnic genome-wide association study of colorectal cancer identifies a new susceptibility locus in VTI1A. 25105248 2014
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma
0.110 GeneticVariation disease BEFREE Multivariate regression analysis results indicated that the AA genotype of VTI1A (rs7086803) polymorphism was associated with an increased risk of developing non-small cell lung carcinoma (NSCLC) compared with the GG genotype (AA vs. GG: odds ratio [OR] = 2.020; 95% confidence interval [95% CI], 1.033-3.949, p = 0.037). 25744365 2015