|
Proliferative vitreoretinopathy
|
0.020 |
Biomarker
|
disease |
BEFREE |
Proliferative vitreoretinopathy vitreous stimulated the production of chemokine (C-C motif) ligand (CCL)2, chemokine (C-X-C motif) ligand (CXCL)8, granulocyte-macrophage colony-stimulating factor (GM-CSF), IL-6, and platelet-derived growth factor (PDGF)-BB by ARPE-19 to significantly (P < 0.05) higher levels than vitreous from the RRD1 and RRD2 groups.
|
25015355 |
2014 |
|
Juvenile Myelomonocytic Leukemia
|
0.400 |
Biomarker
|
disease |
BEFREE |
Juvenile myelomonocytic leukemia (JMML) is an aggressive leukemia of early childhood characterized by aberrant proliferation of myelomonocytic cells and hypersensitivity to GM-CSF stimulation.
|
27447965 |
2016 |
|
Neurodegeneration Due To Cerebral Folate Transport Deficiency
|
0.010 |
AlteredExpression
|
phenotype |
BEFREE |
Cerebral folate deficiency (N=12) was most common, with normal serum folate levels and low CSF 5-methyltetrahydrofolate (5-MTHF) levels.
|
27523499 |
2017 |
|
Hematuria
|
0.020 |
Biomarker
|
phenotype |
BEFREE |
Blood, urine and CSF samples, ALS Functional Rating Scale-Revised (ALSFRS-R) scores and forced vital capacity (FVC) were obtained throughout the trial.
|
27589995 |
2017 |
|
Disseminated cryptococcosis
|
0.010 |
Biomarker
|
disease |
BEFREE |
Disseminated Cryptococcosis Due to Anti-Granulocyte-Macrophage Colony-Stimulating Factor Autoantibodies in the Absence of Pulmonary Alveolar Proteinosis.
|
28013480 |
2017 |
|
Meningitis
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Meningitis (8%) and CSF leakage (3.8%) were the most frequent complications.
|
28059654 |
2017 |
|
Papillary thyroid carcinoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
PTC was defined as presence of intracranial hypertension (CSF opening pressure>25cmH<sub>2</sub>O) and absence of space-occupying lesions in brain MR images.
|
28081975 |
2019 |
|
Alzheimer's Disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
Alzheimer's Disease and the Routine Clinical Use of CSF Biomarkers.
|
28124618 |
2017 |
|
Pulmonary Alveolar Proteinosis
|
0.300 |
Biomarker
|
disease |
BEFREE |
Pulmonary alveolar proteinosis (PAP) is a rare pulmonary disease in which the abnormalities in alveolar surfactant accumulation are caused by impairments of GM-CSF pathway attributing to defects in a variety of genes.
|
28233860 |
2017 |
|
Alzheimer's Disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
Alzheimer's disease (AD) cerebrospinal fluid (CSF) biomarkers have recently been included in the criteria for AD diagnosis.
|
28269771 |
2017 |
|
Arachnoid Cysts
|
0.040 |
Biomarker
|
disease |
BEFREE |
Arachnoid cysts are discrete pockets of CSF or CSF-like fluid found adjacent to normal CSF spaces, either spinal or cranial.
|
28287894 |
2017 |
|
PULMONARY ALVEOLAR PROTEINOSIS, ACQUIRED
|
0.070 |
Biomarker
|
disease |
BEFREE |
Autoimmune pulmonary alveolar proteinosis (aPAP) is a rare disease characterized by the excessive accumulation of surfactant proteins within the alveolar spaces and by higher titers of autoantibodies to granulocyte-macrophage colony-stimulating factor (GM-CSF) in the serum and bronchoalveolar lavage fluid.
|
28421817 |
2017 |
|
Nail-Patella Syndrome
|
0.040 |
Biomarker
|
disease |
BEFREE |
NPS interact with abnormal CSF biomarkers to impact driving performance among cognitively-normal older adults.
|
28453487 |
2017 |
|
Leukemia, Myelomonocytic, Chronic
|
0.050 |
Biomarker
|
disease |
BEFREE |
Chronic myelomonocytic leukemia (CMML) and juvenile myelomonocytic leukemia (JMML) are myelodysplastic syndrome (MDS)/myeloproliferative neoplasm (MPN) overlap disorders characterized by monocytosis, myelodysplasia, and a characteristic hypersensitivity to granulocyte-macrophage colony-stimulating factor (GM-CSF).
|
28576879 |
2017 |
|
Infratentorial Neoplasms
|
0.030 |
Biomarker
|
group |
BEFREE |
Posterior fossa tumors had the highest rate of CSF leakage (32.6%), followed by anterior skull base lesions (21.0%) and sellar/suprasellar lesions (9.9%) (p < 0.0001).
|
28598276 |
2018 |
|
Difficulty sleeping
|
0.020 |
Biomarker
|
phenotype |
BEFREE |
Poor sleep is associated with CSF biomarkers of amyloid pathology in cognitively normal adults.
|
28679595 |
2017 |
|
Hypothalamic Dysfunction Syndromes
|
0.010 |
Biomarker
|
disease |
BEFREE |
Hypothalamic dysfunction is related to sleep impairment and CSF biomarkers in Alzheimer's disease.
|
28900724 |
2017 |
|
Intracranial Hypotension, Essential
|
0.100 |
Biomarker
|
disease |
BEFREE |
Spontaneous intracranial hypotension (SIH) is characterized by orthostatic headache, low CSF pressure and diffuse pachymeningeal enhancement on brain MRI.
|
29052799 |
2018 |
|
Neurological ventriculitis
|
0.040 |
Biomarker
|
disease |
BEFREE |
Ventriculitis was defined as elevated CSF white cell count of > 20/mm<sup>3</sup> or positive CSF culture.
|
29067501 |
2018 |
|
Hydrocephalus, Normal Pressure
|
0.100 |
Biomarker
|
disease |
BEFREE |
Normal pressure hydrocephalus (NPH) is a chronic disorder caused by interrupted CSF absorption or flow.
|
29103634 |
2019 |
|
Cerebral Amyloid Angiopathy
|
0.020 |
Biomarker
|
disease |
BEFREE |
Cerebral amyloid angiopathy-related inflammation (CAA-ri) is associated with a cerebrospinal fluid (CSF) biomarker profile similar to that observed in CAA.
|
29254099 |
2018 |
|
Syringomyelia
|
0.070 |
Biomarker
|
disease |
BEFREE |
Syringomyelia is an abnormal cystic dilatation of the spinal cord caused by excessive accumulation of CSF (cerebrospinal fluid).
|
29316818 |
2018 |
|
Burkitt Lymphoma
|
0.020 |
Biomarker
|
disease |
BEFREE |
Burkitt lymphoma (66%) was commonest histopathological subtype; bone marrow was involved in 15% and CSF in 8% cases.
|
29388861 |
2018 |
|
Adult Burkitt Lymphoma
|
0.020 |
Biomarker
|
disease |
BEFREE |
Burkitt lymphoma (66%) was commonest histopathological subtype; bone marrow was involved in 15% and CSF in 8% cases.
|
29388861 |
2018 |
|
Childhood Burkitt Lymphoma
|
0.020 |
Biomarker
|
disease |
BEFREE |
Burkitt lymphoma (66%) was commonest histopathological subtype; bone marrow was involved in 15% and CSF in 8% cases.
|
29388861 |
2018 |