|
Seminoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
We confirmed the underexpression of heat shock-related 70 kDa protein 2 (P = 0.041), ubiquinol-cytochrome C reductase core protein 2 (P = 0.026), and testis-specific sodium/potassium-transporting ATPase subunit alpha-4 (P = 0.016), as well as the overexpression of angiotensin I converting enzyme (P = 0.005) in the seminoma group.
|
31006710 |
2020 |
|
Autonomic neuropathy
|
0.010 |
Biomarker
|
disease |
BEFREE |
Moreover, the role of ACE inhibition has been explored in the treatment of Cardiovascular Autonomic Neuropathy.
|
31109280 |
2020 |
|
angina symptom
|
0.010 |
GeneticVariation
|
phenotype |
BEFREE |
This allows the assessment of hyperemic MBFs and myocardial flow reserve for the noninvasive identification and characterization of MVD as an important functional substrate for angina symptoms amenable to intensified and individualized medical intervention with nitrates, calcium-channel blockers, statins, angiotensin-converting enzyme inhibitors, and/or angiotensin II type 1 receptor blockers.
|
30982670 |
2020 |
|
Neuropathy, Painful
|
0.010 |
Biomarker
|
disease |
BEFREE |
Treatment of Diabetic Cardiovascular Autonomic, peripheral and painful neuropathy. Focus on the treatment of Cardiovascular Autonomic Neuropathy with ACE inhibitors.
|
31109280 |
2020 |
|
SPHEROCYTOSIS, TYPE 1 (disorder)
|
0.010 |
Biomarker
|
disease |
BEFREE |
This increase might be due to non-HS cancers, which would be associated with an SLE involving greater cumulative damage where more ACE inhibitors are prescribed.
|
31529686 |
2020 |
|
Limb ischemia
|
0.010 |
Biomarker
|
disease |
BEFREE |
Angiotensin Converting Enzyme Inhibitors and Angiotensin II Receptor Blockers (ACEI/ARB) are Associated with Improved Limb Salvage after Infrapopliteal Interventions for Critical Limb Ischemia.
|
31626938 |
2020 |
|
Acne Vulgaris
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
The aim of this work was to reveal the relation between the ACE gene I/D polymorphism and acne vulgaris development among a sample of patients.
|
31033180 |
2019 |
|
Alopecia
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Among cases, serum ACE activity was significantly higher in patients with more severe disease (P = 0.030), nonpatchy alopecia areata (alopecia universalis; ophiasis, patchy and ophiasis, diffuse) (P = 0.029), and with nail involvement (P = 0.027).
|
29582789 |
2019 |
|
Alopecia Areata
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Among cases, serum ACE activity was significantly higher in patients with more severe disease (P = 0.030), nonpatchy alopecia areata (alopecia universalis; ophiasis, patchy and ophiasis, diffuse) (P = 0.029), and with nail involvement (P = 0.027).
|
29582789 |
2019 |
|
Arthralgia
|
0.010 |
GeneticVariation
|
phenotype |
BEFREE |
In addition, the present study made analysis between ACE I/D polymorphism and some clinical features of OA, and found DD genotype of I/D polymorphism was associated with arthralgia.
|
30765613 |
2019 |
|
Burning Mouth Syndrome
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Our study highlighted that ACE inhibitors, ARBs and beta-blockers were in inverse relation to BMS and found that anxiolytics, but neither antidepressants nor antipsychotics, were linked to the presence of the syndrome.
|
31066953 |
2019 |
|
Rectal Carcinoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
The aim of this study was to assess the effect of angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) on tumor response to preoperative chemoradiation for rectal cancer.
|
31252299 |
2019 |
|
Malignant neoplasm of thyroid
|
0.010 |
Biomarker
|
disease |
BEFREE |
We examined in this study the expression of ACE and ACE2 in thyroid tissues and their possible employment as biomarkers for thyroid cancer progression.
|
31847529 |
2019 |
|
CNS disorder
|
0.010 |
AlteredExpression
|
group |
BEFREE |
The pathological axis, consisting of angiotensin II (A1-8), angiotensin converting enzyme (ACE) and the angiotensin II type 1 receptor (AT1R), is upregulated in many CNS diseases, including multiple sclerosis (MS).
|
31828731 |
2019 |
|
Charcot-Marie-Tooth Disease
|
0.010 |
Biomarker
|
disease |
BEFREE |
Our results demonstrate the potential of ACE-083 as a therapeutic agent for patients with CMT, muscular dystrophy and other disorders with focal or asymmetric muscle atrophy or weakness.
|
31388039 |
2019 |
|
Cholestasis
|
0.010 |
Biomarker
|
disease |
BEFREE |
It was reported that hepatotoxicity induced by angiotensin converting enzyme inhibitors (ACEIs) is cholestasis mediated hepatitis.
|
30458228 |
2019 |
|
Dermatitis
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
The extract had inhibitory activity for angiotensin-converting enzyme, which is known as suppression of inflammation of skin, and absorbed electromagnetic radiation in the UVB range.
|
30790328 |
2019 |
|
Diabetic Neuropathies
|
0.010 |
Biomarker
|
group |
BEFREE |
A number of recently identified genes, including the AKR1B1, VEGF, MTHFR, APOE, and ACE genes, contribute significantly in the pathogenesis of DN.
|
31083769 |
2019 |
|
Epilepsy
|
0.010 |
Biomarker
|
disease |
BEFREE |
Experimental and clinical findings related to the involvement of Ang II, ACE, AT<sub>1</sub>, and AT<sub>2</sub> receptors in the control of epilepsy and accompanying complications may point to new therapeutic opportunities and adjuvants for the treatment of common co-morbid conditions of epilepsy.
|
31680223 |
2019 |
|
Hypothyroidism
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Blockade of renin and inhibition of angiotensin-converting enzyme both resulted in a rebound increase in level of renin in hypothyroid rats.
|
31396276 |
2019 |
|
Inappropriate ADH Syndrome
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
Syndrome of inappropriate secretion of antidiuretic hormone associated with angiotensin-converting enzyme inhibitor therapy in the perioperative period.
|
30843458 |
2019 |
|
Infection of kidney
|
0.010 |
Biomarker
|
group |
BEFREE |
The use of angiotensin-converting enzyme inhibitor (ACEI) or angiotensin II receptor blocker (ARB) was significantly associated with renal outcome and infection (renal outcome, hazard ration [HR] 0.06, 95% confidence intervals [CI] 0.01-0.36, P = 0.003; infection, HR 0.20, 95% CI 0.04-0.94, P = 0.041).
|
29525605 |
2019 |
|
Irritable Bowel Syndrome
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Disease outcomes in patients with IBD treated with ACE inhibitors and angiotensin receptor blockers (ARBs) were assessed in retrospective studies.
|
31409604 |
2019 |
|
Keloid
|
0.010 |
Biomarker
|
disease |
BEFREE |
Prorenin receptor and angiotensin II receptor 1 were expressed on the endothelium and the pericyte layer of the microvessels and perivascular cells, angiotensin II receptor 2 was localized to the endothelium of the microvessels and the tryptase-positive perivascular cells, and angiotensin-converting enzyme was localized to the endothelium of the microvessel, within the keloid-associated lymphoid tissues.
|
31348346 |
2019 |
|
Left Bundle-Branch Block
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Previous work has demonstrated that treatment of hypertensive patients with the angiotensin-converting enzyme inhibitor lisinopril was associated with a reduced incidence of a composite conduction system disease endpoint and also left bundle branch block (LBBB) compared with chlorthalidone therapy.
|
30676480 |
2019 |