EDN1, endothelin 1, 1906

N. diseases: 679; N. variants: 23
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0431565
Disease: Hamartoma of tongue
Hamartoma of tongue 		0.100 Biomarker phenotype HPO
CUI: C0476273
Disease: Respiratory distress
Respiratory distress 		0.100 Biomarker phenotype HPO
CUI: C0557874
Disease: Global developmental delay
Global developmental delay 		0.100 Biomarker disease HPO
CUI: C1306710
Disease: Facial asymmetry
Facial asymmetry 		0.100 Biomarker phenotype HPO
CUI: C1840311
Disease: Laryngeal cleft
Laryngeal cleft 		0.100 Biomarker disease HPO
CUI: C1846460
Disease: Abnormality of the outer ear
Abnormality of the outer ear 		0.100 Biomarker disease HPO
CUI: C1853406
Disease: Difficulty in tongue movements
Difficulty in tongue movements 		0.100 Biomarker phenotype HPO
CUI: C1857486
Disease: Low-set, posteriorly rotated ears
Low-set, posteriorly rotated ears 		0.100 Biomarker phenotype HPO
CUI: C1858120
Disease: Generalized hypotonia
Generalized hypotonia 		0.100 Biomarker phenotype HPO
CUI: C1860816
Disease: Preauricular skin tag
Preauricular skin tag 		0.100 Biomarker phenotype HPO
CUI: C1865318
Disease: Abnormality of the temporomandibular joint
Abnormality of the temporomandibular joint 		0.100 Biomarker phenotype HPO
CUI: C1866231
Disease: Full cheeks
Full cheeks 		0.100 Biomarker phenotype HPO
CUI: C3494422
Disease: Retrognathia
Retrognathia 		0.100 Biomarker disease HPO
CUI: C4021376
Disease: Cleft helix
Cleft helix 		0.100 Biomarker phenotype HPO
CUI: C4021380
Disease: Abnormality of the crus of the helix
Abnormality of the crus of the helix 		0.100 Biomarker phenotype HPO
CUI: C4022171
Disease: Periauricular skin pits
Periauricular skin pits 		0.100 Biomarker disease HPO
CUI: C4024626
Disease: Aplasia/Hypoplasia of the external ear
Aplasia/Hypoplasia of the external ear 		0.100 Biomarker phenotype HPO
CUI: C4551488
Disease: Bifid uvula
Bifid uvula 		0.100 Biomarker disease HPO
CUI: C0020649
Disease: Hypotension
Hypotension 		0.310 Therapeutic phenotype CTD_human Evidence for antagonistic activity of endothelin for clonidine induced hypotension and bradycardia. 1309933 1992
CUI: C0428977
Disease: Bradycardia
Bradycardia 		0.300 Therapeutic phenotype CTD_human Evidence for antagonistic activity of endothelin for clonidine induced hypotension and bradycardia. 1309933 1992
CUI: C1153706
Disease: Endometrial adenocarcinoma
Endometrial adenocarcinoma 		0.010 AlteredExpression disease BEFREE The expression of endothelin-1 (ET-1) in five human endometrial adenocarcinoma cell lines was studied. 1587391 1992
CUI: C0035222
Disease: Respiratory Distress Syndrome, Adult
Respiratory Distress Syndrome, Adult 		0.510 Biomarker disease RGD Release of endothelin in the oleic acid-induced respiratory distress syndrome in rats. 1618274 1992
CUI: C0007103
Disease: Malignant neoplasm of endometrium
Malignant neoplasm of endometrium 		0.010 AlteredExpression disease BEFREE PreproET-1 mRNA is present in HEC-1A cells, and immunoreactive endothelin is secreted into the medium of these cells maintained in culture. 1732042 1992
CUI: C0476089
Disease: Endometrial Carcinoma
Endometrial Carcinoma 		0.010 AlteredExpression disease BEFREE PreproET-1 mRNA is present in HEC-1A cells, and immunoreactive endothelin is secreted into the medium of these cells maintained in culture. 1732042 1992
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.020 Biomarker group BEFREE Paraffin sections of 66 surgically resected lung tumours were immunostained with antisera to human endothelin-1 and to the C-terminal peptide of big endothelin. 2231187 1990