|
Carcinoma
|
0.100 |
Biomarker
|
group |
BEFREE |
The human epidermal growth factor (EGF) receptor (HER) family is frequently overexpressed in the majority of human carcinomas, and is involved in promoting the proliferation and survival of cancer cells.
|
30008917 |
2018 |
|
Carcinoma
|
0.100 |
Biomarker
|
group |
BEFREE |
EGF Level in Hepatoid Gland Adenomas and Hepatoid Gland Epitheliomas in Dogs After Administering Tamoxifen.
|
30150441 |
2018 |
|
Carcinoma
|
0.100 |
AlteredExpression
|
group |
BEFREE |
The expression of epidermal growth factor (EGF) receptors is common in human carcinomas and the proteins are used as therapeutics targets.
|
29556616 |
2017 |
|
Carcinoma
|
0.100 |
PosttranslationalModification
|
group |
BEFREE |
EGF and EGFR are involved in many aspects of the development of carcinomas.
|
28501600 |
2017 |
|
Carcinoma
|
0.100 |
AlteredExpression
|
group |
BEFREE |
The EGF receptor (EGFR) is expressed in most cases of anal carcinomas.
|
25244542 |
2015 |
|
Carcinoma
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Dlk1, a member of the Epidermal Growth Factor family, is expressed in multiple tissues during development, and has been detected in carcinomas and neuroendocrine tumors.
|
23577150 |
2013 |
|
Carcinoma
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Molecular imaging of active mutant L858R EGF receptor (EGFR) kinase-expressing nonsmall cell lung carcinomas using PET/CT.
|
21220318 |
2011 |
|
Carcinoma
|
0.100 |
GeneticVariation
|
group |
BEFREE |
EGF promoter polymorphisms are observed to modulate EGF levels and thought to have effect on susceptibility to various carcinomas but the results are inconsistent.
|
20033794 |
2010 |
|
Carcinoma
|
0.100 |
AlteredExpression
|
group |
BEFREE |
The epidermal growth factor (EGF)-ErbB-mitogen-activated protein kinase (MAPK) transcription signaling pathway is altered in many types of carcinomas, and this pathway can be regulated by new protein-protein interactions.
|
20679487 |
2010 |
|
Carcinoma
|
0.100 |
Biomarker
|
group |
BEFREE |
EGF is known to affect adherens junctions and disrupt cell-cell adhesion in a variety of carcinomas but the underlying mechanisms are not completely understood.
|
19591825 |
2009 |
|
Carcinoma
|
0.100 |
Biomarker
|
group |
BEFREE |
The human gene Teratocarcinoma-derived growth factor 1 (TDGF1)/Cripto-1/CR-1 which is expressed in a wide variety of human carcinomas is a member of the EGF-cripto FRL1 cryptic (EGF-CFC) gene family.
|
17291450 |
2007 |
|
Carcinoma
|
0.100 |
AlteredExpression
|
group |
BEFREE |
The EGFR and EGF-like peptides are often over-expressed in human carcinomas, and in vivo and in vitro studies have shown that these proteins are able to induce cell transformation.
|
16377102 |
2006 |
|
Carcinoma
|
0.100 |
Biomarker
|
group |
BEFREE |
Epidermal growth factor (EGF) receptor (EGFR)-mediated motility, present in both autocrine and paracrine modes in prostate carcinomas, requires de novo transcription to persist over times greater than a few hours.
|
16804520 |
2006 |
|
Carcinoma
|
0.100 |
Biomarker
|
group |
BEFREE |
The over-expression of epidermal growth factor receptor (EGFR) and its ligands, epidermal growth factor (EGF) and transforming growth factor-alpha, is a common feature of epithelial carcinomas and correlates with neoplastic progression.
|
15642791 |
2005 |
|
Carcinoma
|
0.100 |
Biomarker
|
group |
BEFREE |
From the observed clonal differences in the regulatory effects of EGF and 1,25-D3 on VDR and CYP27B1 gene expression we suggest that VDR-mediated growth inhibition by 1,25-D3 would be efficient only in highly differentiated carcinomas even when under mitogenic stimulation by EGF.
|
12027461 |
2002 |
|
Carcinoma
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Upregulated epidermal growth factor (EGF) receptor (EGFR) expression and EGFR-induced signaling have been correlated with progression to invasion and metastasis in a wide variety of carcinomas, but the mechanism behind this is not well understood.
|
11359909 |
2001 |
|
Carcinoma
|
0.100 |
AlteredExpression
|
group |
BEFREE |
All carcinomas and synchronous lesions but one showed high expression levels of the EGF receptor.
|
10534770 |
1999 |
|
Carcinoma
|
0.100 |
Biomarker
|
group |
BEFREE |
The EGF-like family of proteins, such as epidermal growth factor (EGF), transforming growth factor alpha (TGFalpha), amphiregulin (AR), betacellulin (BTC), cripto-1 (CR-1), and heregulin (HRG), plays an important role in the pathogenesis of several human carcinomas as autocrine growth factors.
|
9648926 |
1998 |
|
Carcinoma
|
0.100 |
Biomarker
|
group |
BEFREE |
The expression of cripto, a member of the epidermal growth factor (EGF) family, was examined by immunohistochemistry in benign lesions and carcinomas of the gall bladder.
|
8976875 |
1996 |
|
Carcinoma
|
0.100 |
AlteredExpression
|
group |
BEFREE |
A significantly higher incidence (P < 0.05) of expression of the following was noted; TGF-alpha in the polypoid carcinomas with an adenoma component, and EGF and c-ERBB2 gene product in the carcinomas without an adenoma component.
|
8669884 |
1996 |
|
Carcinoma
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Epidermal growth factor expression in human colon and colon carcinomas: anti-sense epidermal growth factor receptor RNA down-regulates the proliferation of human colon cancer cells.
|
7558411 |
1995 |
|
Carcinoma
|
0.100 |
Biomarker
|
group |
BEFREE |
EGF expression was unevenly distributed according to histological grade, indicating a lack of EGF immunoreactivity in poorly differentiated oesophageal carcinomas.
|
8166440 |
1994 |
|
Carcinoma
|
0.100 |
Biomarker
|
group |
BEFREE |
Expression of amphiregulin, a novel gene of the epidermal growth factor family, in human gastric carcinomas.
|
8407551 |
1993 |
|
Carcinoma
|
0.100 |
Biomarker
|
group |
BEFREE |
The expression of mRNAs for epidermal growth factor (EGF), transforming growth factor alpha(TGF alpha), EGFR, platelet-derived growth factor (PDGF) A and B chain, PDGF receptor (PDGFR), transforming growth factor beta (TGF beta), erbB-2 and estrogen receptor (ER) genes was first examined in 6 human esophageal carcinoma cell lines, 6 xenoplanted and 15 surgically resected esophageal carcinomas.
|
8491760 |
1993 |
|
Carcinoma
|
0.100 |
AlteredExpression
|
group |
BEFREE |
The expression of pre-pro-TGF-alpha mRNA and pre-pro-EGF mRNA were significantly higher in CaP (n = 13) than BPH (n = 21) specimens (p < 0.05).
|
7508078 |
1993 |