|
Asthma
|
0.110 |
Biomarker
|
disease |
BEFREE |
By linking DEGs to the genome-wide association study (GWAS) catalog and the lung and blood eQTL annotation data from GTEx, we identified four male-specific genes (FBXL7, ITPR3 and RAD51B from epithelial tissue and ALOX15 from blood) and one female-specific gene (HLA-DQA1 from epithelial tissue) that are disregulated during asthma.
|
31095684 |
2019 |
|
Asthma
|
0.110 |
GeneticVariation
|
disease |
GWASCAT |
Genome-Wide Association Study Identifies Novel Loci Associated With Diisocyanate-Induced Occupational Asthma.
|
25918132 |
2015 |
|
Asthma
|
0.110 |
GeneticVariation
|
disease |
GWASCAT |
Genetic predictors associated with improvement of asthma symptoms in response to inhaled corticosteroids.
|
24486069 |
2014 |
|
Adverse effects, not elsewhere classified
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Genetic variation in the Estonian population: pharmacogenomics study of adverse drug effects using electronic health records.
|
30420678 |
2019 |
|
Diabetes Mellitus, Non-Insulin-Dependent
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Genetic Variants in HSD17B3, SMAD3, and IPO11 Impact Circulating Lipids in Response to Fenofibrate in Individuals With Type 2 Diabetes.
|
28736931 |
2018 |
|
response to simvastatin
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Genetic Variants in HSD17B3, SMAD3, and IPO11 Impact Circulating Lipids in Response to Fenofibrate in Individuals With Type 2 Diabetes.
|
28736931 |
2018 |
|
Alzheimer's Disease
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
F-box/LRR-repeat protein 7 is genetically associated with Alzheimer's disease.
|
26339675 |
2015 |
|
Chronic Obstructive Airway Disease
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
|
26634245 |
2015 |
|
response to bronchodilator
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
|
26634245 |
2015 |
|
Polysomnography
|
0.100 |
GeneticVariation
|
phenotype |
GWASDB |
Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
|
23251661 |
2012 |
|
Hormone measurement
|
0.100 |
GeneticVariation
|
group |
GWASCAT |
Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
|
23251661 |
2012 |
|
Malignant neoplasm of stomach
|
0.010 |
Biomarker
|
disease |
BEFREE |
Aurora kinase A regulates Survivin stability through targeting FBXL7 in gastric cancer drug resistance and prognosis.
|
28218735 |
2017 |
|
Adenocarcinoma of lung (disorder)
|
0.010 |
Biomarker
|
disease |
BEFREE |
Seven core transcription factors (MCM4, VWF, ECT2, RBMS3, LIMCH1, MYBL2 and FBXL7) are detected, and have been reported to contribute to tumorigenesis of lung adenocarcinoma.
|
28377053 |
2017 |
|
Carcinogenesis
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
Seven core transcription factors (MCM4, VWF, ECT2, RBMS3, LIMCH1, MYBL2 and FBXL7) are detected, and have been reported to contribute to tumorigenesis of lung adenocarcinoma.
|
28377053 |
2017 |
|
Stomach Carcinoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
Aurora kinase A regulates Survivin stability through targeting FBXL7 in gastric cancer drug resistance and prognosis.
|
28218735 |
2017 |
|
Malignant neoplasm of breast
|
0.010 |
Biomarker
|
disease |
BEFREE |
In addition, integrating pathway and gene information, we identified five (ID4, ANXA4, CXCL9, MYLK, FBXL7) and six (SQLE, E2F1, PTTG1, TSTA3, BUB1B, MAD2L1) known cancer genes significant for ovarian and breast cancer respectively.
|
22759382 |
2012 |
|
Breast Carcinoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
In addition, integrating pathway and gene information, we identified five (ID4, ANXA4, CXCL9, MYLK, FBXL7) and six (SQLE, E2F1, PTTG1, TSTA3, BUB1B, MAD2L1) known cancer genes significant for ovarian and breast cancer respectively.
|
22759382 |
2012 |