Developmental delay (disorder)
|
0.310 |
Biomarker
|
phenotype |
GENOMICS_ENGLAND |
Amino acid uptake by the mammary gland of the lactating ewe.
|
678219 |
1978 |
Global developmental delay
|
0.310 |
Biomarker
|
disease |
GENOMICS_ENGLAND |
Amino acid uptake by the mammary gland of the lactating ewe.
|
678219 |
1978 |
Intellectual Disability
|
0.300 |
Biomarker
|
group |
GENOMICS_ENGLAND |
Amino acid uptake by the mammary gland of the lactating ewe.
|
678219 |
1978 |
Anxiety Disorders
|
0.320 |
Biomarker
|
group |
CTD_human |
Targeted deletion of the GABRA2 gene encoding alpha2-subunits of GABA(A) receptors facilitates performance of a conditioned emotional response, and abolishes anxiolytic effects of benzodiazepines and barbiturates.
|
18313124 |
2008 |
Anxiety States, Neurotic
|
0.300 |
Biomarker
|
disease |
CTD_human |
Targeted deletion of the GABRA2 gene encoding alpha2-subunits of GABA(A) receptors facilitates performance of a conditioned emotional response, and abolishes anxiolytic effects of benzodiazepines and barbiturates.
|
18313124 |
2008 |
Anxiety neurosis (finding)
|
0.300 |
Biomarker
|
disease |
CTD_human |
Targeted deletion of the GABRA2 gene encoding alpha2-subunits of GABA(A) receptors facilitates performance of a conditioned emotional response, and abolishes anxiolytic effects of benzodiazepines and barbiturates.
|
18313124 |
2008 |
Cannabis use
|
0.310 |
Biomarker
|
disease |
PSYGENET |
Genes such as ELTD1 on chromosome 1, in addition to genes on chromosomes 4 (eg, GABRA2) and 6 (eg, CNR1), may be associated with the genetic risk for cannabis use disorders.
|
18519829 |
2008 |
Autistic Disorder
|
0.300 |
Biomarker
|
disease |
CTD_human |
GABA(A) receptor downregulation in brains of subjects with autism.
|
18821008 |
2009 |
Cannabis Dependence
|
0.320 |
Biomarker
|
disease |
PSYGENET |
We conclude that genetic variation at or near the GABRA2 locus significantly affects vulnerability not only to AD, but to other forms of substance use including ND and CD, and that the effects may be sex dependent.
|
19672139 |
2009 |
Cocaine Dependence
|
0.550 |
Biomarker
|
disease |
PSYGENET |
The influence of GABRA2, childhood trauma, and their interaction on alcohol, heroin, and cocaine dependence.
|
19833324 |
2010 |
Cocaine Dependence
|
0.550 |
Biomarker
|
disease |
CTD_human |
The influence of GABRA2, childhood trauma, and their interaction on alcohol, heroin, and cocaine dependence.
|
19833324 |
2010 |
Cocaine Abuse
|
0.300 |
Biomarker
|
disease |
CTD_human |
The influence of GABRA2, childhood trauma, and their interaction on alcohol, heroin, and cocaine dependence.
|
19833324 |
2010 |
Heroin Dependence
|
0.300 |
Biomarker
|
disease |
CTD_human |
The influence of GABRA2, childhood trauma, and their interaction on alcohol, heroin, and cocaine dependence.
|
19833324 |
2010 |
Cocaine-Related Disorders
|
0.300 |
Biomarker
|
group |
CTD_human |
The influence of GABRA2, childhood trauma, and their interaction on alcohol, heroin, and cocaine dependence.
|
19833324 |
2010 |
heroin abuse
|
0.300 |
Biomarker
|
disease |
CTD_human |
The influence of GABRA2, childhood trauma, and their interaction on alcohol, heroin, and cocaine dependence.
|
19833324 |
2010 |
Heroin Smoking
|
0.300 |
Biomarker
|
disease |
CTD_human |
The influence of GABRA2, childhood trauma, and their interaction on alcohol, heroin, and cocaine dependence.
|
19833324 |
2010 |
Cocaine Dependence
|
0.550 |
Biomarker
|
disease |
PSYGENET |
Consistent with a role of these receptors in addiction, we found specific markers and haplotypes of the GABRA2 gene to be associated with human cocaine addiction.
|
20133874 |
2010 |
Cocaine Dependence
|
0.550 |
Biomarker
|
disease |
CTD_human |
Consistent with a role of these receptors in addiction, we found specific markers and haplotypes of the GABRA2 gene to be associated with human cocaine addiction.
|
20133874 |
2010 |
Cocaine Abuse
|
0.300 |
Biomarker
|
disease |
CTD_human |
Cocaine effects on mouse incentive-learning and human addiction are linked to alpha2 subunit-containing GABAA receptors.
|
20133874 |
2010 |
Cocaine-Related Disorders
|
0.300 |
Biomarker
|
group |
CTD_human |
Cocaine effects on mouse incentive-learning and human addiction are linked to alpha2 subunit-containing GABAA receptors.
|
20133874 |
2010 |
Alcoholic Intoxication, Chronic
|
0.700 |
Biomarker
|
disease |
CTD_human |
GABAergic gene expression in postmortem hippocampus from alcoholics and cocaine addicts; corresponding findings in alcohol-naïve P and NP rats.
|
22253714 |
2012 |
Alcohol Use Disorder
|
0.400 |
Biomarker
|
disease |
CTD_human |
GABAergic gene expression in postmortem hippocampus from alcoholics and cocaine addicts; corresponding findings in alcohol-naïve P and NP rats.
|
22253714 |
2012 |
Alcohol abuse
|
0.320 |
Biomarker
|
disease |
CTD_human |
GABAergic gene expression in postmortem hippocampus from alcoholics and cocaine addicts; corresponding findings in alcohol-naïve P and NP rats.
|
22253714 |
2012 |
Cocaine Dependence
|
0.550 |
Biomarker
|
disease |
PSYGENET |
Genetic association of GABA-A receptor alpha-2 and mu opioid receptor with cocaine cue-reactivity: evidence for inhibitory synaptic neurotransmission involvement in cocaine dependence.
|
22882391 |
2013 |
Alcoholic Intoxication, Chronic
|
0.700 |
Biomarker
|
disease |
PSYGENET |
In this study, we test for genetic effects of GABRA2, a gene previously associated with alcohol dependence, on trajectories of drunkenness from age 14 to 25.
|
23692184 |
2014 |