|
Obesity
|
0.400 |
Biomarker
|
disease |
BEFREE |
The potential for a genetic marker of obesity creates opportunities for future studies in the Inuit, not just to confirm the associations, but also to examine prospectively the influence of interventions and possible relationships between GNB3 825T and longer term complications of obesity.
|
10523525 |
1999 |
|
Obesity
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The G protein beta 3 subunit 825T allele was recently found to be associated with hypertension and obesity which makes it a sensible candidate gene for type 2 diabetes.
|
11121369 |
2000 |
|
Obesity
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The 825T-allele of the gene GNB3 encoding the G protein beta3 subunit is associated with hypertension and obesity, and identifies individuals highly responsive to diuretic therapy.
|
11927836 |
2002 |
|
Obesity
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
A polymorphism (C825T) in the gene encoding the G protein beta3 subunit (GNB3) has recently been associated with hypertension and obesity in several populations.
|
12109775 |
2002 |
|
Obesity
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The GNB3 C825T gene polymorphism has recently been identified and associated with hypertension, obesity and left ventricular hypertrophy.
|
12566975 |
2003 |
|
Obesity
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The C825T dimorphism of the gene encoding the human G protein beta3 subunit (GNB3) is associated with hypertension and obesity.
|
12624279 |
2003 |
|
Obesity
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The C825T polymorphism of the G-protein beta(3) subunit gene, known to be associated with obesity, is a determinant of weight gain during pregnancy.
|
12668921 |
2003 |
|
Obesity
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The 825T-allele of the C825T polymorphism in GNB3, the gene for the G protein beta3 subunit, has been reported to be associated with essential hypertension and obesity.
|
12730030 |
2003 |
|
Obesity
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Therefore our work does not provide evidence in favor of GNB3 C825T being a candidate gene for conferring genetic susceptibility to hypertension or obesity in northern Chinese population.
|
13679998 |
2003 |
|
Obesity
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The 825T allele of the GNB3 gene has been associated with essential hypertension and obesity in cross-sectional studies.
|
14557282 |
2003 |
|
Obesity
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The C825T polymorphism in the gene coding for the beta3 subunit of G proteins (GNB3) has been shown to be associated with several phenotypes such as hypertension, obesity, and diabetes mellitus comprising the metabolic syndrome.
|
15033462 |
2004 |
|
Obesity
|
0.400 |
Biomarker
|
disease |
BEFREE |
In summary, the presence of obesity reveals an association between blood pressure and the GNB3 gene in White females.
|
15226674 |
2004 |
|
Obesity
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Both the gene encoding the alpha subunit of G stimulatory proteins (GNAS1) and the beta3 subunit gene (GNB3) of G proteins are associated with obesity and/or hypertension.
|
15531240 |
2004 |
|
Obesity
|
0.400 |
Biomarker
|
disease |
CTD_human |
Insulin-mediated venodilation is impaired in young, healthy carriers of the 825T allele of the G-protein beta3 subunit gene (GNB3).
|
15961981 |
2005 |
|
Obesity
|
0.400 |
Biomarker
|
disease |
CTD_human |
C825T polymorphism in the human G protein beta3 subunit gene is associated with long-term clozapine treatment-induced body weight change in the Chinese population.
|
16141801 |
2005 |
|
Obesity
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Hypertension, obesity and GNB 3 gene variants.
|
16487269 |
2006 |
|
Obesity
|
0.400 |
Biomarker
|
disease |
BEFREE |
The potential effect of variants in three catecholaminergic pathway genes (ADRB2, ADRB3, and GNB3) on obesity-related traits was investigated in an European-derived Brazilian population.
|
16493638 |
2006 |
|
Obesity
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The C825T variant of the G-protein beta3 subunit (GNB3) gene has attracted renewed attention as a candidate gene for obesity, hypertension and hyperuricemia.
|
16707857 |
2006 |
|
Obesity
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Thus, we investigated how genetic variation in the GNB3 gene is associated with hypertension, obesity, insulin resistance, diabetes, diabetic complications, and diabetic therapies in 427 Japanese subjects with type 2 diabetes mellitus and in 368 Japanese subjects who underwent general health examinations.
|
17161225 |
2007 |
|
Obesity
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Our findings suggest that the variation within the GNB3 gene may interact with physical activity level to influence obesity status and, together with obesity and physical activity, the GNB3 825C>T variant may influence hypertension prevalence in AAs.
|
17299380 |
2007 |
|
Obesity
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The 825T allele of the GNB3 gene is implicated in adipose distribution, predisposing to obesity and hypertension.
|
18192837 |
2008 |
|
Obesity
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
It has been reported that C825T variant in the gene encoding the G-protein subunit beta3 (GNB3) is associated with antipsychotic-induced weight gain and obesity.
|
18793692 |
2008 |
|
Obesity
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The 825T allele of the G protein beta3-subunit gene (GNB3) is a thrifty genotype associated with an increased risk for obesity.
|
19420911 |
2009 |
|
Obesity
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Weight loss and body fat reduction under sibutramine therapy in obesity with the C825T polymorphism in the GNB3 gene.
|
19687782 |
2009 |
|
Obesity
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The aim of the study was to examine the association between the G protein β3 subunit C825T polymorphism, associated with cardiovascular risk factors like hypertension (HT) and obesity and microalbuminuria (MA), reflecting the endothelial dysfunction in the atherosclerotic process.
|
20577224 |
2010 |