Abortion, Tubal
|
0.300 |
Biomarker
|
phenotype |
CTD_human |
Gene expression in cultured endometrium from women with different outcomes following IVF.
|
18539642 |
2008 |
Acute and chronic colitis
|
0.010 |
Biomarker
|
disease |
BEFREE |
IL-9 deficiency suppressed acute and chronic colitis.
|
24908389 |
2014 |
Acute appendicitis NOS (disorder)
|
0.010 |
Biomarker
|
disease |
BEFREE |
Here, we propose the concept of appendicular lavage and use it to study the levels of the Th2 cytokines IL-4, IL-5, and IL-9 in patients with a clinical diagnosis of acute appendicitis.
|
31772507 |
2019 |
Acute Coronary Syndrome
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
In addition, CD4(+)IL-9(+) T cells and IL-9 were increased in patients with acute coronary syndrome, and the levels of IL-9 in culture supernatants and soluble VCAM-1 (sVCAM-1) in plasma were significantly positively correlated in the enrolled patients.
|
25784693 |
2015 |
Acute GVH disease
|
0.030 |
Biomarker
|
disease |
BEFREE |
Serum IFN-γ/IL-9 ratios increased linearly with grades of aGVHD.
|
28861153 |
2017 |
Acute GVH disease
|
0.030 |
AlteredExpression
|
disease |
BEFREE |
Moreover, serum IFN-gamma, IL-17, and IL-9 levels were higher in aGVHD patients with high miR-155.
|
24494749 |
2014 |
Acute GVH disease
|
0.030 |
Biomarker
|
disease |
BEFREE |
By using p40-deficient mice, we found that both donor- and host-derived p40 contribute to the development of aGVHD.
|
25846718 |
2015 |
Acute HIV infection
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Significant reduction in transcription of IL-12 p40 was observed following acute HIV infection.
|
12202149 |
2002 |
Acute interstitial nephritis
|
0.010 |
Biomarker
|
disease |
BEFREE |
Urine TNF-α and IL-9 for clinical diagnosis of acute interstitial nephritis.
|
31092735 |
2019 |
Adamantinoma
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Adamantinoma-like Ewing sarcoma (ALES) is a rare tumor that demonstrates the EWSR1-FLI1 translocation characteristic of Ewing sarcoma despite overt epithelial differentiation including diffuse expression of cytokeratins and p40.
|
30285997 |
2019 |
Adenocarcinoma
|
0.100 |
Biomarker
|
group |
BEFREE |
Utility of p63 and p40 in Distinguishing Polymorphous Adenocarcinoma and Adenoid Cystic Carcinoma.
|
31653135 |
2019 |
Adenocarcinoma
|
0.100 |
Biomarker
|
group |
BEFREE |
TTF-1 and napsin A IHC stainings had similar specificity but better sensitivity for adenocarcinoma than the mucin stains, but addition of PASD or ABPAS identified more tumors as adenocarcinomas (n = 8 and n = 10, respectively) than napsin A (n = 1) in cases with solid growth that were negative for TTF-1 and p40.
|
30718697 |
2019 |
Adenocarcinoma
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Spatial proximity between bronchus and ALK-rearranged tumors and frequent solid histologic subtype with p63 expression may cause diagnostic difficulties to differentiate squamous cell carcinoma in the small biopsy, whereas p40 was rarely expressed in ALK-rearranged adenocarcinoma.
|
24194854 |
2013 |
Adenocarcinoma
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Once a broad tumor class is established, more specific differentiation markers can be pursued (e.g., lineage-restricted transcription factors for adenocarcinoma; p40 for squamous cell carcinoma; chromogranin A and synaptophysin or INSM1 for neuroendocrine neoplasms).
|
31786484 |
2020 |
Adenocarcinoma
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Polyclonal p40 yields a level of false positivity in ACAs similar to p63, which is highest in effusions and is not limited to lung origin.
|
28498881 |
2017 |
Adenocarcinoma
|
0.100 |
Biomarker
|
group |
BEFREE |
Diagnostic combinations were p40-/TTF1+ or TTF1- for AD (where p40 was negative, apart from 5/30 AD showing at the best 1-2% tumor cells with low intensity); p40+/TTF1- (p40 strong and by far higher than 50%) for SQC; and p40+/TTF1+ or p40+/TTF1- (p40 strong and less than 50%) for ADSQC.
|
22071786 |
2012 |
Adenocarcinoma
|
0.100 |
Biomarker
|
group |
BEFREE |
We characterized captured cells using TTF1 and p40 as immunostaining biomarkers of adenocarcinoma and squamous cell carcinoma, respectively.
|
28298147 |
2017 |
Adenocarcinoma
|
0.100 |
Biomarker
|
group |
BEFREE |
Cell differentiation lineages were unveiled by using thyroid transcription factor-1 (TTF1) for adenocarcinoma (ADC) and p40 for squamous cell carcinoma (SQC), dichotomizing immunohistochemistry (IHC) results for TTF1 as negative or positive (whatever its extent) and for p40 as negative, positive, or focal (if <10% of reactive tumor cells).
|
26317919 |
2015 |
Adenocarcinoma
|
0.100 |
Biomarker
|
group |
BEFREE |
Confirmatory fluorescence in-situ hybridization (FISH) using a break-apart probe to the TP63 gene region and immunohistochemistry for p63 and p40 were performed on adenocarcinomas with TP63 rearrangements identified by mate-pair sequencing.
|
25189640 |
2015 |
Adenocarcinoma
|
0.100 |
Biomarker
|
group |
BEFREE |
We evaluated expression of Sox10 and DOG1 in normal cutaneous adnexa and in 194 primary skin adnexal tumors, and compared their performance in discriminating primary skin adnexal tumors from cutaneous metastatic adenocarcinomas with that of p40 and p63.
|
28394798 |
2017 |
Adenocarcinoma of lung (disorder)
|
0.020 |
Biomarker
|
disease |
BEFREE |
The IL-9-expressing Th9 cells are recently found to present antitumor immunity in melanoma and lung adenocarcinoma.
|
28918288 |
2017 |
Adenocarcinoma of lung (disorder)
|
0.020 |
Biomarker
|
disease |
BEFREE |
We performed immunohistochemistry for CDX-2, CK7, CK20, TTF-1, napsin A, and p40 using 4-μm sections of a previously constructed tissue microarray containing 93 primary lung adenocarcinomas that lack morphologic evidence of enteric differentiation.
|
26469326 |
2016 |
Adenoid Cystic Carcinoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
Utility of p63 and p40 in Distinguishing Polymorphous Adenocarcinoma and Adenoid Cystic Carcinoma.
|
31653135 |
2019 |
Adenoma
|
0.010 |
AlteredExpression
|
group |
BEFREE |
Cytoplasmic/membranous expression of IL-23 (p19 and p40 subunits) and IL-23R, respectively were over-expressed in carcinomas versus adenomas and normal tissues (p<0.0001) but were reduced in lymph node metastases (p<0.0001).
|
25015728 |
2014 |
Adenosquamous carcinoma
|
0.030 |
Biomarker
|
disease |
BEFREE |
Diagnostic combinations were p40-/TTF1+ or TTF1- for AD (where p40 was negative, apart from 5/30 AD showing at the best 1-2% tumor cells with low intensity); p40+/TTF1- (p40 strong and by far higher than 50%) for SQC; and p40+/TTF1+ or p40+/TTF1- (p40 strong and less than 50%) for ADSQC.
|
22071786 |
2012 |