IL9, interleukin 9, 3578

N. diseases: 291; N. variants: 4
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0018553
Disease: Hamartoma Syndrome, Multiple
Hamartoma Syndrome, Multiple
0.010 Biomarker disease BEFREE Ustekinumab (UST) is an antibody to the p40 subunit of interleukins 12 and 23 in Crohn's disease (CD) patients. 31722356 2020
CUI: C0042029
Disease: Urinary tract infection
Urinary tract infection
0.010 Biomarker group BEFREE Urinary proteins that best discriminated between children with UTI and no UTI were involved in T cell response proliferation (IL-9, IL-2), chemoattractants (CXCL12, CXCL1, CXCL8), the cytokine/interferon pathway (IL-13, IL-2, INFγ), or involved in innate immunity (NGAL). 31758242 2020
Infection caused by Helicobacter pylori
0.010 AlteredExpression disease BEFREE This study seeks to investigate the possible functions of Tc9, Th9 cells, and IL-9 level in patients with inflammation due to H pylori infection. 31803999 2020
CUI: C0002448
Disease: Ameloblastoma
Ameloblastoma
0.010 GeneticVariation disease BEFREE Adamantinoma-like Ewing sarcoma (ALES) is a rare tumor that demonstrates the EWSR1-FLI1 translocation characteristic of Ewing sarcoma despite overt epithelial differentiation including diffuse expression of cytokeratins and p40. 30285997 2019
CUI: C0003615
Disease: Appendicitis
Appendicitis
0.010 Biomarker disease BEFREE The difference was more pronounced when comparing phlegmonous appendicitis with nonpathological appendicitis (<i>p</i> = 0.01) for IL-4 (48.3 vs. 21.3 pg/mL), IL-5 (29.2 vs. 8.0 pg/mL), and IL-9 (34.1 vs. 16.6 pg/mL). 31772507 2019
CUI: C0004238
Disease: Atrial Fibrillation
Atrial Fibrillation
0.010 Biomarker disease BEFREE We aimed to evaluate the predictive value of three inflammatory biomarkers (interleukin [IL]-9, IL-10, and interferon [IFN]-γ) for stroke and mortality in atrial fibrillation. 31813744 2019
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.010 Biomarker disease BEFREE IL-9 Exerts Antitumor Effects in Colon Cancer and Transforms the Tumor Microenvironment <i>In Vivo</i>. 31242804 2019
CUI: C0010606
Disease: Adenoid Cystic Carcinoma
Adenoid Cystic Carcinoma
0.010 Biomarker disease BEFREE Utility of p63 and p40 in Distinguishing Polymorphous Adenocarcinoma and Adenoid Cystic Carcinoma. 31653135 2019
CUI: C0011991
Disease: Diarrhea
Diarrhea
0.010 AlteredExpression phenotype BEFREE Clinical signs (anorexia, somnolence, fever and diarrhea), bacterial interference and translocation, intestinal histopathology, transcriptions of claudin-1, occludin and interferon (IFN)-γ, intestinal and systemic protein levels of interleukin (IL)-8, IL-12/23 p40 and IFN-γ were compared among (i) germ-free, (ii) LGG-colonized, (iii) ST-infected and (iv) LGG-colonized and subsequently ST-infected piglets for 24 h. Both LGG and ST-colonized the GIT; LGG translocated in some cases into mesenteric lymph nodes and the spleen but did not cause bacteremia and clinical changes. 30422309 2019
CUI: C0014175
Disease: Endometriosis
Endometriosis
0.010 AlteredExpression disease BEFREE A significantly increased expression of IL-9, Gro<sub>α</sub> , and SDF-1<sub>α</sub> (P < 0.05) was observed in the presence of endometriosis, while high levels of IL-13 and L-15 were associated with ovulatory infertility factor (P < 0.05). 30475413 2019
CUI: C0021053
Disease: Immune System Diseases
Immune System Diseases
0.010 Biomarker group BEFREE Features and roles of T helper 9 cells and interleukin 9 in immunological diseases. 29703631 2019
CUI: C0022658
Disease: Kidney Diseases
Kidney Diseases
0.010 AlteredExpression group BEFREE Participants with AIN had consistently higher levels of urine TNF-α and IL-9 than those with other diagnoses, including acute tubular injury, glomerular diseases, and diabetic kidney disease, and those without any kidney disease. 31092735 2019
CUI: C0023281
Disease: Leishmaniasis
Leishmaniasis
0.010 Biomarker disease BEFREE IL12 p35 and p40 subunit genes administered as pPAL plasmid constructs do not improve protection of pPAL-LACK vaccine against canine leishmaniasis. 30794597 2019
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms
0.010 Biomarker group BEFREE Moreover, supplementary immunohistochemical staining of liver tumor indicated p63 and p40 were strongly positive, that confirmed the liver tumor was metastatic BSCC. 31488173 2019
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.010 Biomarker disease BEFREE Effect of Th9/IL-9 on the growth of gastric cancer in nude mice. 30988627 2019
CUI: C0085693
Disease: Acute appendicitis NOS (disorder)
Acute appendicitis NOS (disorder)
0.010 Biomarker disease BEFREE Here, we propose the concept of appendicular lavage and use it to study the levels of the Th2 cytokines IL-4, IL-5, and IL-9 in patients with a clinical diagnosis of acute appendicitis. 31772507 2019
CUI: C0149925
Disease: Small cell carcinoma of lung
Small cell carcinoma of lung
0.010 AlteredExpression disease BEFREE Although p40 was not diffusely expressed in any of the SCLC cases, p40-positive cells were observed in the tumors in 15 cases (34.1%). 30957413 2019
CUI: C0149937
Disease: Acute interstitial nephritis
Acute interstitial nephritis
0.010 Biomarker disease BEFREE Urine TNF-α and IL-9 for clinical diagnosis of acute interstitial nephritis. 31092735 2019
CUI: C0151650
Disease: Renal fibrosis
Renal fibrosis
0.010 Biomarker disease BEFREE We aimed to evaluate the role of IL-9 in the course of hepatic and renal fibrosis. 30887397 2019
CUI: C0162871
Disease: Aortic Aneurysm, Abdominal
Aortic Aneurysm, Abdominal
0.010 Biomarker disease BEFREE Since IL-12 and IL-23 are related cytokines that share the common p40 subunit, we also evaluate the effect of direct IL-23 blockade on the development of AAA. 31320700 2019
CUI: C0206754
Disease: Neuroendocrine Tumors
Neuroendocrine Tumors
0.010 Biomarker group BEFREE TTF-1 and napsin A for lung adenocarcinoma, p40 for squamous lung cancer, GATA3 and mammaglobin for breast cancer, or synaptophysin and chromogranin A for neuroendocrine tumors). 30354850 2019
CUI: C0524909
Disease: Hepatitis B, Chronic
Hepatitis B, Chronic
0.010 Biomarker disease BEFREE Interleukin-9 has been shown to contribute to liver fibrosis in patients with chronic hepatitis B and in a mouse model due to carbon tetrachloride. 31436861 2019
CUI: C0553580
Disease: Ewings sarcoma
Ewings sarcoma
0.010 AlteredExpression disease BEFREE Adamantinoma-like Ewing sarcoma (ALES) is a rare tumor that demonstrates the EWSR1-FLI1 translocation characteristic of Ewing sarcoma despite overt epithelial differentiation including diffuse expression of cytokeratins and p40. 30285997 2019
CUI: C0699790
Disease: Colon Carcinoma
Colon Carcinoma
0.010 AlteredExpression disease BEFREE Here, interleukin 9 protein and messenger RNA expression levels were both low in colon carcinoma tissue specimens, as assessed by immunohistochemistry and quantitative real-time polymerase chain reaction. 31242804 2019
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma
0.010 Biomarker disease BEFREE Effect of Th9/IL-9 on the growth of gastric cancer in nude mice. 30988627 2019