Brain Ischemia
|
0.510 |
Biomarker
|
disease |
BEFREE |
BHD suppressed brain ischemia-induced interferon-γ and chemokine CXCL10 production.
|
30355926 |
2018 |
Brain Ischemia
|
0.510 |
Biomarker
|
disease |
RGD |
Minocycline modulates chemokine receptors but not interleukin-10 mRNA expression in hypoxic-ischemic neonatal rat brain.
|
17549754 |
2007 |
Brain Ischemia
|
0.510 |
Biomarker
|
disease |
CTD_human |
Superoxide dismutase 1 overexpression reduces MCP-1 and MIP-1 alpha expression after transient focal cerebral ischemia.
|
15829914 |
2005 |
Influenza
|
0.380 |
Biomarker
|
disease |
BEFREE |
Notably, CXCL-10 had the highest area under the receiver operating characteristic curve (AUC) in differentiating rhinovirus from influenza patients (AUC, 0.918).
|
29454786 |
2018 |
Influenza
|
0.380 |
AlteredExpression
|
disease |
BEFREE |
Higher frequencies of CD11b+ inflammatory monocytes (CD11b(hi), >48.4%) compared with low frequencies of CD11b+ inflammatory monocytes (<15.8%) was associated with higher prevaccination frequencies of total and inflammatory monocytes and higher CCR2 MFI, higher plasma sTNFR1 and CXCL-10 with higher lipopolysaccharide stimulated expression of TNFα and IL-6, concomitant with lower postvaccination influenza antibody titers.
|
29683844 |
2018 |
Influenza
|
0.380 |
Biomarker
|
disease |
BEFREE |
In addition, it can significantly attenuate expression of the pro-inflammatory molecules IL-6, MIP-1β, MCP-1, and IP-10 induced by human influenza A virus (H1N1) and similarly downregulate expression of cytokines and chemokines induced by avian influenza A virus (H9N2).
|
29035328 |
2017 |
Influenza
|
0.380 |
AlteredExpression
|
disease |
BEFREE |
In this study, we demonstrate the synergistic stimulation of CXCL10 mRNA and protein, a key chemokine responsible for the early immune response to viral infection, following treatment of airway epithelial cells with IFN γ and influenza virus.
|
25033426 |
2014 |
Influenza
|
0.380 |
Biomarker
|
disease |
CTD_human |
A host transcriptional signature for presymptomatic detection of infection in humans exposed to influenza H1N1 or H3N2.
|
23326326 |
2013 |
Influenza
|
0.380 |
Biomarker
|
disease |
BEFREE |
In A549 cells, the extract (30 µg/mL) significantly inhibited influenza virus induced monocyte chemotactic protein (MCP)-1 and interferon-γ induced protein 10 kD (IP-10), but dramatically increased interleukin-6 (IL-6).
|
24098792 |
2013 |
Influenza
|
0.380 |
AlteredExpression
|
disease |
BEFREE |
Only 9% of subjects who received LAIV seroconverted, while 33% of patients developed at least a 2-fold increase in influenza virus-specific immunoglobulin A (IgA) antibodies in nasal wash. LAIV induced a localized inflammation, as suggested by increased expression of interferon-response genes in mucosal RNA and increased granulocyte colony-stimulating factor (G-CSF) and IP-10 in nasal wash. Interestingly, patients who seroconverted had significantly lower serum levels of G-CSF before vaccination.
|
23087433 |
2013 |
Influenza
|
0.380 |
Biomarker
|
disease |
BEFREE |
In comparison with human seasonal influenza H1N1 (A/HK/54/98) and mouse adapted influenza H1N1 (A/WSN/33) viruses, the highly pathogenic influenza H5N1 virus (A/HK/483/97) was a more potent inducer of the chemokine, CXCL 10 (IP-10), while there was not a clear differential TNF-α protein expression pattern.
|
23226456 |
2012 |
Influenza
|
0.380 |
Biomarker
|
disease |
BEFREE |
Furthermore, NEC/mono-DC co-cultures using NECs from smokers exhibited suppressed concentrations of T-cell/natural killer cell chemokine interferon gamma-induced protein 10 (IP-10) after infection with influenza, indicating that NECs from smokers may skew early influenza-induced Th1 responses.
|
20935192 |
2011 |
Dermatitis, Atopic
|
0.350 |
Biomarker
|
disease |
BEFREE |
T<sub>H</sub>2 chemokines (CCL13, CCL17) were consistently elevated in patients with AD across all ages (P < .05), whereas T<sub>H</sub>1 (CXCL10) and T<sub>H</sub>17 (KYNU, CCL20) markers incrementally increased with age in both patients with AD and healthy subjects.
|
31622668 |
2020 |
Dermatitis, Atopic
|
0.350 |
AlteredExpression
|
disease |
BEFREE |
Interleukin (IL)-1β, IL-18, C-X-C motif chemokine (CXCL) 8 (CXCL8), C-C motif chemokine ligand (CCL) 22 (CCL22), CCL17, CXCL10 and CCL2 were significantly higher (P < 0·05) in lesional AD skin compared with nonlesional AD skin; the opposite trend was seen for IL-1α.
|
29989151 |
2019 |
Dermatitis, Atopic
|
0.350 |
AlteredExpression
|
disease |
BEFREE |
IP-10 levels in ISF from lesional and non-lesional AD skin showed significant correlation with IP-10 blood levels.
|
25980674 |
2015 |
Dermatitis, Atopic
|
0.350 |
Biomarker
|
disease |
CTD_human |
Peroxisome proliferator-activated receptor alpha regulates skin inflammation and humoral response in atopic dermatitis.
|
18249437 |
2008 |
Dermatitis, Atopic
|
0.350 |
AlteredExpression
|
disease |
BEFREE |
To determine whether a different pattern of production of IP-10 by fibroblasts corresponds to the level of this chemokine in the plasma of patients with AD, we also checked the plasma IP-10 levels in 33 AD patients and 10 healthy donors.
|
15149503 |
2004 |
Dermatitis, Atopic
|
0.350 |
Biomarker
|
disease |
BEFREE |
IP-10 and IL-8 were consistently upregulated in the epidermis of patients with psoriasis but not in lesions of patients with AD.
|
11344355 |
2001 |
Celiac Disease
|
0.340 |
Biomarker
|
disease |
BEFREE |
The role of CXCR3 and its ligands CXCL10 and CXCL11 in the pathogenesis of celiac disease.
|
31232926 |
2019 |
Celiac Disease
|
0.340 |
AlteredExpression
|
disease |
BEFREE |
TG2-specific compared to non-TG2 specific PCs expressed increased levels of CXCR3, CXCL10 and interleukin-15; factors that have been implicated in the pathogenesis of CeD yet with production attributed to other cells than PCs.
|
31839965 |
2019 |
Celiac Disease
|
0.340 |
Biomarker
|
disease |
BEFREE |
Selected biomarkers were able to classify subjects with clear CD/non-CD status, and a subset of the biomarkers (CXCL10, GBP5, IFI27, IFNG, and UBD) showed differential expression in biopsies from subjects with no or low-grade intestinal injury that received a CD diagnosis based on biopsies taken at a later time point.
|
30097691 |
2018 |
Celiac Disease
|
0.340 |
AlteredExpression
|
disease |
BEFREE |
Increased IFN-γ and IP-10 levels after challenge were observed in patients with CD, but not in controls.
|
29903545 |
2018 |
Celiac Disease
|
0.340 |
Biomarker
|
disease |
CTD_human |
Selected biomarkers were able to classify subjects with clear CD/non-CD status, and a subset of the biomarkers (CXCL10, GBP5, IFI27, IFNG, and UBD) showed differential expression in biopsies from subjects with no or low-grade intestinal injury that received a CD diagnosis based on biopsies taken at a later time point.
|
30097691 |
2018 |
Primary biliary cirrhosis
|
0.330 |
Biomarker
|
disease |
BEFREE |
In serum of PBC patients there was a significant increase of MIG and IP-10 compared to NCs.
|
23480180 |
2013 |
Primary biliary cirrhosis
|
0.330 |
Biomarker
|
disease |
CTD_human |
Gene expression profiling of early primary biliary cirrhosis: possible insights into the mechanism of action of ursodeoxycholic acid.
|
18422935 |
2008 |