|
Breast Carcinoma
|
0.040 |
AlteredExpression
|
disease |
BEFREE |
In breast cancer patients, miR-338-3p expression negatively correlates with the expression of EGFR and EYA2, EGFR status positively associates with EYA2 expression, and miR-338-3p and EYA2 predict breast cancer lung metastasis when expressed in primary breast cancers.
|
28703807 |
2017 |
|
Breast Carcinoma
|
0.040 |
Biomarker
|
disease |
BEFREE |
Altogether, our results provide novel evidence on the molecular mechanisms by which E2 may regulate miR-338-3p toward breast cancer progression.
|
30423928 |
2018 |
|
Breast Carcinoma
|
0.040 |
AlteredExpression
|
disease |
BEFREE |
We measured expression levels of circ_0008945, miR-338-3p and homeobox A3 (<i>HOXA3</i>) in BC tissue specimens and cells using quantitative reverse transcriptase polymerase chain reaction (qRT-PCR).
|
31496747 |
2019 |
|
Breast Carcinoma
|
0.040 |
Biomarker
|
disease |
BEFREE |
These findings revealed that miR‑338-3p may act as a tumor suppressor in breast cancer by targeting SOX4, suggesting miR‑338-3p as a novel strategy for breast cancer treatment.
|
26252944 |
2015 |
|
Carcinogenesis
|
0.030 |
Biomarker
|
phenotype |
BEFREE |
miR‑338‑3p, a recently discovered miRNA, has been shown to play important roles in tumorigenesis and metastasis in various cancers.
|
25776272 |
2015 |
|
Carcinogenesis
|
0.030 |
Biomarker
|
phenotype |
BEFREE |
The proliferation, migration, and invasion of SACC-83 cells also decreased after hsa_circ_0059655 knock-downed.Taken together, the circRNAs derived from PYGB may regulate the tumorigenesis and development of SACC through competing with miR-338-3p.
|
30672444 |
2018 |
|
Carcinogenesis
|
0.030 |
Biomarker
|
phenotype |
BEFREE |
SNHG1 conduced to tumorigenesis and mechanism by upregulating PLK4 and by acting as miR-338-3p sponge in neuroblastoma.
|
31696485 |
2019 |
|
Carcinoma of bladder
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
miR-338-3p and ETS1 expressions were examined by quantitative Real-time polymerase chain reaction (qRT-PCR) in BC samples.
|
30915741 |
2019 |
|
Carcinoma of lung
|
0.060 |
Biomarker
|
disease |
BEFREE |
MicroRNA-338-3p (miR‑338-3p), a recently discovered miRNA, has been reported to be downregulated and play tumor suppressor roles in gastric cancer, ovarian cancer, colorectal carcinoma and lung cancer by targeting several genes.
|
26252944 |
2015 |
|
Carcinoma of lung
|
0.060 |
Biomarker
|
disease |
BEFREE |
However, the role of miR‑338-3p in lung cancer, particularly non‑small‑cell lung carcinoma (NSCLC), has remained elusive.
|
25374067 |
2015 |
|
Carcinoma of lung
|
0.060 |
Biomarker
|
disease |
BEFREE |
Therapeutically, miR-338-3p may serve as a potential target in the treatment of human lung cancer.
|
28428733 |
2017 |
|
Carcinoma of lung
|
0.060 |
AlteredExpression
|
disease |
BEFREE |
Previous studies suggested microRNA-338-3p (miR-338-3p) was down-regulated and play tumor suppressor roles in gastric cancer, colorectal carcinoma and lung cancer.
|
25755720 |
2015 |
|
Carcinoma of lung
|
0.060 |
Biomarker
|
disease |
BEFREE |
Our results reveal a new regulatory mechanism of miR-338 which may help us better understand the metastasis of lung cancer.
|
27431198 |
2016 |
|
Carcinoma of lung
|
0.060 |
Biomarker
|
disease |
BEFREE |
The present findings supported the potential use of miR‑338‑3p in the treatment of lung cancer.
|
31115502 |
2019 |
|
Carcinoma, Ovarian Epithelial
|
0.030 |
AlteredExpression
|
disease |
BEFREE |
We first showed that the expression of miR‑338‑3p was significantly downregulated in EOC tissues compared to those in adjacent normal tissues, and the value was negatively related to advanced FIGO stage, high histological grading and lymph node metastasis (P<0.01).
|
25776272 |
2015 |
|
Carcinoma, Ovarian Epithelial
|
0.030 |
AlteredExpression
|
disease |
BEFREE |
<b>Objective</b> To detect the expression of microRNA-338-3p (miR-338-3p) and MET transcriptional regulator MACC1 (MACC1) gene in different ovarian tissues, to analyze their relationships, their correlations to the clinicopathologic characteristics of epithelial ovarian cancer and their significant to the progression of ovarian cancer.
|
31031848 |
2019 |
|
Carcinoma, Ovarian Epithelial
|
0.030 |
AlteredExpression
|
disease |
BEFREE |
Furthermore, overexpression of miR-338-3p increased cisplatin sensitivity among ovarian cancer in an in vivo xenograft tumor model.
|
31769245 |
2019 |
|
Central neuroblastoma
|
0.030 |
Biomarker
|
disease |
BEFREE |
Reconstruction of a NB network comprising MIR152, MIR200B, and MIR338 allowed us to confirm their role in the control of NB cell stemness and apoptosis: This suggests that altered regulation of these MIRs could have a role in NB pathogenesis by interfering with the molecular mechanisms, which physiologically control differentiation and death of neuroblasts.
|
20574809 |
2010 |
|
Central neuroblastoma
|
0.030 |
Biomarker
|
disease |
BEFREE |
SNHG1 conduced to tumorigenesis and mechanism by upregulating PLK4 and by acting as miR-338-3p sponge in neuroblastoma.
|
31696485 |
2019 |
|
Central neuroblastoma
|
0.030 |
Biomarker
|
disease |
BEFREE |
This newly identified function of miR-338-3p provides novel insights into neuroblastoma and may foster therapeutic applications.
|
24140344 |
2013 |
|
cervical cancer
|
0.020 |
Biomarker
|
disease |
BEFREE |
We explored the association of miR-338-3p expression with pathology and prognosis in cervical cancer patients.
|
29243777 |
2017 |
|
cervical cancer
|
0.020 |
Biomarker
|
disease |
BEFREE |
Given that autophagy is an important factor promoting tumor progression, we aim to investigate the functional role of miR-338 in autophagy and proliferation of cervical cancer.
|
29898430 |
2018 |
|
Cervix carcinoma
|
0.020 |
Biomarker
|
disease |
BEFREE |
We explored the association of miR-338-3p expression with pathology and prognosis in cervical cancer patients.
|
29243777 |
2017 |
|
Cervix carcinoma
|
0.020 |
Biomarker
|
disease |
BEFREE |
Given that autophagy is an important factor promoting tumor progression, we aim to investigate the functional role of miR-338 in autophagy and proliferation of cervical cancer.
|
29898430 |
2018 |
|
Chemical and Drug Induced Liver Injury
|
0.300 |
Biomarker
|
disease |
CTD_human |
"Serum microRNA signatures as ""liquid biopsies"" for interrogating hepatotoxic mechanisms and liver pathogenesis in human."
|
28545106 |
2017 |